Abstract: In one aspect, a biological sequencing device comprising a cartridge configured to be removed from the instrument is disclosed. In various embodiments the cartridge can include one or more capillaries suitable for capillary electrophoresis, a reservoir and a pump. In various embodiments the reservoir can contain a separation matrix. In various embodiments the pump can load a capillary with separation matrix. In another aspect the biological sequencing device can include one or more capillaries and an integrated valve assembly. In various embodiments the integrated valve assembly can provide a polymer to the one or more capillaries.

Abstract: A biological analysis device for performing capillary electrophoresis includes a voltage section configured to generate a voltage differential across a cathode connector and an anode connector, an optical detector system configured to detect light emission from a sample, a temperature regulation section, and a cartridge holding portion configured to receive at least a portion of a removable cartridge comprising one or more capillaries and a separation medium container. The biological analysis device may include one or more actuators configured to actuate components of the removable cartridge when the removable cartridge is received in the cartridge holding portion. Devices and methods relate to biological analysis.

Abstract: In one aspect, a biological sequencing device comprising a cartridge configured to be removed from the instrument is disclosed. In various embodiments the cartridge can include one or more capillaries suitable for capillary electrophoresis, a reservoir and a pump. In various embodiments the reservoir can contain a separation matrix. In various embodiments the pump can load a capillary with separation matrix. In another aspect the biological sequencing device can include one or more capillaries and an integrated valve assembly. In various embodiments the integrated valve assembly can provide a polymer to the one or more capillaries.

Abstract: In one aspect, a biological sequencing device comprising a cartridge configured to be removed from the instrument is disclosed. In various embodiments the cartridge can include one or more capillaries suitable for capillary electrophoresis, a reservoir and a pump. In various embodiments the reservoir can contain a separation matrix. In various embodiments the pump can load a capillary with separation matrix. In another aspect the biological sequencing device can include one or more capillaries and an integrated valve assembly. In various embodiments the integrated valve assembly can provide a polymer to the one or more capillaries.

Abstract: A biological analysis device (100) for performing capillary electrophoresis includes a voltage section (124) configured to generate a voltage differential across a cathode (106) connector and an anode (116) connector, an optical detector system (112) configured to detect light emission from a sample, a temperature regulation section (126), and a cartridge holding portion configured to receive at least a portion of a removable cartridge (102) comprising one or more capillaries (104) and a separation medium container (118). The biological analysis device may include one or more actuators (122) configured to actuate components of the removable cartridge when the removable cartridge is received in the cartridge holding portion. Devices and methods relate to biological analysis.

Abstract: The present disclosure relates, in some embodiments, to an apparatus for conducting a capillary electrophoresis assay. The apparatus can comprise a capillary array comprising an anode end and a cathode end, the capillary array provided in a housing further comprising a reservoir configured to house a separation medium and an anode buffer. The system can also comprise an injection mechanism configured to deliver sample to the cathode end of the capillary array, and a temperature control zone, wherein the temperature control zone is configured to control the temperature of the interior of the housing.

Abstract: In one aspect, a biological sequencing device comprising a cartridge configured to be removed from the instrument is disclosed. In various embodiments the cartridge can include one or more capillaries suitable for capillary electrophoresis, a reservoir and a pump. In various embodiments the reservoir can contain a separation matrix. In various embodiments the pump can load a capillary with separation matrix. In another aspect the biological sequencing device can include one or more capillaries and an integrated valve assembly. In various embodiments the integrated valve assembly can provide a polymer to the one or more capillaries.

Abstract: The present disclosure relates, in some embodiments, to an apparatus for conducting a capillary electrophoresis assay. The apparatus can comprise a capillary array comprising an anode end and a cathode end, the capillary array provided in a housing further comprising a reservoir configured to house a separation medium and an anode buffer. The system can also comprise an injection mechanism configured to deliver sample to the cathode end of the capillary array, and a temperature control zone, wherein the temperature control zone is configured to control the temperature of the interior of the housing.

Abstract: Method and system for obtaining and using observed market rates in estimating suitable market-based compensation for one or more jobs. Each observed market rate is assigned a job family and a combination of a job category and a job level of responsibility (C/L). Median market rates and average market rates are observed for different job families and are combined in a novel way to produce job family factors and C/L factors that, when multiplied together accurately reflect market rates for that job, even for a combination of job family and job C/L that is not represented in the data.