Patents by Inventor Alexander Dvornikov

Alexander Dvornikov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220236109
    Abstract: An imaging system comprises an excitation light source, a directing element positioned to direct light from the excitation light source toward a sample, a detector configured to measure incoming light from the sample, a filter cavity positioned between the sample and the detector, a first filter configured to be inserted into the filter cavity, a sine filter configured to be inserted into the filter cavity, and a processing unit communicatively connected to the detector, configured to receive image data from the detector to form an image. Methods of constructing a hyperspectral image of a sample are also described.
    Type: Application
    Filed: April 19, 2022
    Publication date: July 28, 2022
    Inventors: Enrico Gratton, Alexander Dvornikov
  • Patent number: 11307094
    Abstract: An imaging system comprises an excitation light source, a directing element positioned to direct light from the excitation light source toward a sample, a detector configured to measure incoming light from the sample, a filter cavity positioned between the sample and the detector, a first filter configured to be inserted into the filter cavity, a sine filter configured to be inserted into the filter cavity, and a processing unit communicatively connected to the detector, configured to receive image data from the detector to form an image. Methods of constructing a hyperspectral image of a sample are also described.
    Type: Grant
    Filed: May 28, 2020
    Date of Patent: April 19, 2022
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Enrico Gratton, Alexander Dvornikov
  • Publication number: 20200378830
    Abstract: An imaging system comprises an excitation light source, a directing element positioned to direct light from the excitation light source toward a sample, a detector configured to measure incoming light from the sample, a filter cavity positioned between the sample and the detector, a first filter configured to be inserted into the filter cavity, a sine filter configured to be inserted into the filter cavity, and a processing unit communicatively connected to the detector, configured to receive image data from the detector to form an image. Methods of constructing a hyperspectral image of a sample are also described.
    Type: Application
    Filed: May 28, 2020
    Publication date: December 3, 2020
    Inventors: Enrico Gratton, Alexander Dvornikov
  • Patent number: 8692998
    Abstract: An apparatus and method for in-depth fluorescence imaging using two-photon fluorescence imaging in turbid media. The apparatus includes a detector which can significantly enhance the use of a detection method that allows to efficiently collect scattered fluorescence photons from a wide area of the turbid sample. By using this detector it is possible to perform imaging of turbid samples, simulating brain tissue at depths up to 3 mm, where the two-photon induced fluorescence signal is too weak to be detected by previous means used in conventional two-photon microscopy. The detector separates the excitation and detection optics which allows a more efficient collection of fluorescence and enhancing the possible imaging depth.
    Type: Grant
    Filed: April 11, 2012
    Date of Patent: April 8, 2014
    Assignee: The Regents of the University of California
    Inventors: Enrico Gratton, Alexander Dvornikov, Viera Crosignani
  • Publication number: 20120257203
    Abstract: An apparatus and method for in-depth fluorescence imaging using two-photon fluorescence imaging in turbid media. The apparatus includes a detector which can significantly enhance the use of a detection method that allows to efficiently collect scattered fluorescence photons from a wide area of the turbid sample. By using this detector it is possible to perform imaging of turbid samples, simulating brain tissue at depths up to 3 mm, where the two-photon induced fluorescence signal is too weak to be detected by previous means used in conventional two-photon microscopy. The detector separates the excitation and detection optics which allows a more efficient collection of fluorescence and enhancing the possible imaging depth.
    Type: Application
    Filed: April 11, 2012
    Publication date: October 11, 2012
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Enrico Gratton, Alexander Dvornikov, Viera Crosignani
  • Publication number: 20080057328
    Abstract: A piracy protection digital recording medium comprising a polymeric layer incorporating an optical state change material in conjunction with a cationic photoinitiator.
    Type: Application
    Filed: June 26, 2007
    Publication date: March 6, 2008
    Inventors: Peter Rentzepis, Richard Selinfreund, Craig Etchegoyen, Alexander Dvornikov
  • Publication number: 20080035503
    Abstract: A storage case of storing optical digital data storage media, the case including a cover with a defined area therein that permits transmission of certain energy to the medium stored therein while the area of the cover outside of the defined area does not.
    Type: Application
    Filed: June 26, 2007
    Publication date: February 14, 2008
    Inventors: Peter Rentzepis, Richard Selinfreund, Craig Etchegoyen, Alexander Dvornikov
  • Patent number: 6693201
    Abstract: Photochromic chemicals consisting essentially of colored fluorescent heterocyclic fulgides are particularly suitable for optical memories. The preferred heterocyclic photochromic fulgides consist essentially of colored 2-indolyfulgides capable of excitation by ultraviolet light to fluoresce. These heterocyclic photochromic fulgides are preferably synthesized by process of (1) condensation of 1,3-dimethyl-(5-substituted)indole-2-carboxaldehyde with diethyl IV iospropylidenesuccinate as a key intermediate; followed by (2) hydrolysis; and (3) intramolecular acid anhydride formation.
    Type: Grant
    Filed: September 7, 1999
    Date of Patent: February 17, 2004
    Assignee: The Regents Of the University of California
    Inventors: Peter M. Rentzepis, Alexander Dvornikov
  • Publication number: 20030073031
    Abstract: Dye precursor molecules—normally rhodamine base—held in a transparent matrix are reactive with acids, bases, ions or radicals—and in the case of rhodamine are reactive with acids—to produce dye molecules—i.e., rhodamine—having markedly different spectroscopic properties. Light-sensitive molecules—normally a compound of ortho-nitro-aldehyde, in particular o-nitro-benzaldehyde or, preferably, 1-nitro-2-naphthaldehyde—in the same matrix undergo photochemical reaction when selectively exposed to light so as to form at least one of the acids, bases, ions or radicals with which the dye precursor molecules are reactive—preferably nitroso acid.
    Type: Application
    Filed: August 13, 2002
    Publication date: April 17, 2003
    Inventors: Peter M. Rentzepis, Alexander Dvornikov
  • Patent number: 6432610
    Abstract: Dye precursor molecules—normally rhodamine base—held in a transparent matrix are reactive with acids, bases, ions or radicals—and in the case of rhodamine are reactive with acids—to produce dye molecules—i.e., rhodamine—having markedly different spectroscopic properties. Light-sensitive molecules-normally a compound of ortho-nitro-aldehyde, in particular o-nitro-benzaldehyde or, preferably, 1-nitro-2-naphthaldehyde—in the same matrix undergo photochemical reaction when selectively exposed to light so as to form at least one of the acids, bases, ions or radicals with which the dye precursor molecules are reactive—preferably nitroso acid.
    Type: Grant
    Filed: September 7, 1999
    Date of Patent: August 13, 2002
    Assignee: Regents of the University of California
    Inventors: Peter M. Rentzepis, Alexander Dvornikov
  • Patent number: 5734498
    Abstract: An inexpensive, simple and easy-to-use illuminator element--consisting of chromophores, particularly fluorophores, and/or light-scattering bodies in a stable, typically a polymer plastic, matrix--completely replaces an infinite set of condensers for a optical microscope, and works equally well with microscope objective lenses of any and all numerical apertures. Illuminator elements of a fluorescent type are employed in combination with a primary source of light that is external to the illuminator element itself, and that is preferably but a simple incandescent light bulb. Nonetheless to be energized with spectrally impure light, each illuminator element produces spectrally pure light(s) of a predetermined color or colors, including a pseudo-white light. Sets of illuminator elements permit the ready production of colored light(s) of any desired spectral characteristics from primary light sources that are no more sophisticated, nor any more expensive, than common electric light bulbs.
    Type: Grant
    Filed: May 9, 1994
    Date of Patent: March 31, 1998
    Assignee: The Regents of the University of California
    Inventors: Tatiana Krasieva, Bruce Tromberg, Alexander Dvornikov, Michael W. Berns