Patents by Inventor Alexander Flohr

Alexander Flohr has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Carbamic acid esters of benzothiazoles
    Publication number: 20040235842
    Abstract: The present invention relates to a compound of formula I 1
    Type: Application
    Filed: May 18, 2004
    Publication date: November 25, 2004
    Inventors: Alexander Flohr, Roland Jakob-Roetne, Roger David Norcross, Claus Riemer
  • Benzothiazole derivatives
    Publication number: 20040235915
    Abstract: This invention relates to compounds of formula I 1
    Type: Application
    Filed: May 17, 2004
    Publication date: November 25, 2004
    Inventors: Alexander Flohr, Roland Jakob-Roetne, Roger David Norcross, Claus Riemer
  • Imidazo-benzothiazoles
    Publication number: 20040229862
    Abstract: The invention relates to 2-imidazo-benzothiazoles of general formula 1
    Type: Application
    Filed: May 11, 2004
    Publication date: November 18, 2004
    Inventors: Alexander Flohr, Roland Jakob-Roetne, Roger David Norcross, Claus Riemer
  • Substituted benzothiazole amide derivatives
    Publication number: 20040229893
    Abstract: A compound of formula I and a method of treatment of diseases, related to modulation of the adenosine A2 receptor system comprising administering a compound of formula 1
    Type: Application
    Filed: October 23, 2003
    Publication date: November 18, 2004
    Inventors: Alexander Flohr, Roland Jakob-Roetne, Roger David Norcross, Claus Riemer
  • ADENOSINE RECEPTOR LIGANDS
    Publication number: 20040204584
    Abstract: The present invention relates to compounds of the general formula I 1
    Type: Application
    Filed: March 30, 2004
    Publication date: October 14, 2004
    Inventors: Alexander Flohr, Roger David Norcross
  • Benzothiazoles
    Patent number: 6734179
    Abstract: The present invention relates to compounds of the formula wherein R1 and R2 are as described within. The compounds of formula I have been found to be adenosine receptor ligands. Specifically, the compounds of the present invention have a good affinity to the A2A-receptor and they may be used in the treatment of diseases, related to this receptor.
    Type: Grant
    Filed: December 2, 2002
    Date of Patent: May 11, 2004
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Alexander Flohr, Roland Jakob-Roetne, Roger David Norcross, Claus Riemer
  • 7-phenyl-benzo[b]thiophen amide derivatives
    Patent number: 6730670
    Abstract: A compound of the formula Compounds of formula I have a good affinity to the A2A receptor and are useful for the treatment of diseases mediated by this receptor.
    Type: Grant
    Filed: December 10, 2002
    Date of Patent: May 4, 2004
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Alexander Alanine, Alexander Flohr
  • Substituted benzothiazole amide derivatives
    Patent number: 6727247
    Abstract: A compound of formula I and a method of treatment of diseases, related to modulation of the adenosine A2 receptor system comprising administering a compound of formula to a person in need of such treatment.
    Type: Grant
    Filed: December 3, 2002
    Date of Patent: April 27, 2004
    Assignee: Hoffman-La Roche Inc.
    Inventors: Alexander Flohr, Roland Jakob-Roetne, Roger David Norcross, Claus Riemer
  • 7-Amino-benzothiazole derivatives
    Patent number: 6713499
    Abstract: The present invention relates to compounds of the formula wherein R1, R2 and R3 are as described herewithin. The compounds of formula I have been found to be adenosine receptor ligands. Specifically, the compounds of the present invention have a good affinity to the A2A-receptor and they are therefore useful in the treatment of diseases, related to this receptor.
    Type: Grant
    Filed: December 2, 2002
    Date of Patent: March 30, 2004
    Assignee: Hoffman-La Roche Inc.
    Inventors: Alexander Flohr, Roland Jakob-Roetne, Roger David Norcross, Claus Riemer
  • Benzothiazole derivatives
    Patent number: 6624163
    Abstract: The present invention relates to compounds of the formula wherein R1 and R2 are as defined herewithin. The compounds of formula I have been found to be adenosine receptor ligands. Specifically, the compounds of the present invention have a good affinity to the A2A-receptor and they are therefore useful in the treatment of diseases, related to this receptor.
    Type: Grant
    Filed: November 15, 2002
    Date of Patent: September 23, 2003
    Assignee: Hoffman-La Roche Inc.
    Inventors: Alexander Flohr, Roland Jakob-Roetne, Roger David Norcross, Claus Riemer
  • Benzothiazole derivatives with activity as adenosine receptor ligands
    Publication number: 20030176695
    Abstract: The present invention relates to substituted benzothiazole derivitives and to their pharmaceutically acceptable salts useful for the treatment of diseases related to the adenosine receptor.
    Type: Application
    Filed: December 18, 2002
    Publication date: September 18, 2003
    Inventors: Alexander Alanine, Alexander Flohr, Aubry Kern Miller, Roger David Norcross, Claus Riemer
  • Isonicotin- and nicotinamide derivatives of benzothiazoles
    Patent number: 6620811
    Abstract: The present invention relates to compounds of the formula wherein R1, A and R are as described within. The compounds of the present invention have been found to be adenosine receptor ligands. Specifically, the compounds of the present invention have an affinity to the A2A-receptor and are therefore useful in the treatment of diseases related to this receptor.
    Type: Grant
    Filed: November 5, 2002
    Date of Patent: September 16, 2003
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Alexander Flohr, Roland Jakob-Roetne, Roger David Norcross, Claus Riemer
  • 7-Amino-benzothiazole derivatives
    Publication number: 20030153566
    Abstract: The present invention relates to compounds of the formula 1
    Type: Application
    Filed: December 2, 2002
    Publication date: August 14, 2003
    Inventors: Alexander Flohr, Roland Jakob-Roetne, Roger David Norcross, Claus Riemer
  • 7-phenyl-benzo [b] thiophen amide derivatives
    Publication number: 20030149030
    Abstract: A compound of the formula 1
    Type: Application
    Filed: December 10, 2002
    Publication date: August 7, 2003
    Inventors: Alexander Alanine, Alexander Flohr
  • Substituted benzothiazole amide derivatives
    Publication number: 20030149036
    Abstract: A compound of formula I and a method of treatment of diseases, related to modulation of the adenosine A2 receptor system comprising administering a compound of formula 1
    Type: Application
    Filed: December 3, 2002
    Publication date: August 7, 2003
    Inventors: Alexander Flohr, Roland Jakob-Roetne, Roger D. Norcross, Claus Riemer
  • Benzothiazoles
    Publication number: 20030144288
    Abstract: The present invention relates to compounds of the formula 1
    Type: Application
    Filed: December 2, 2002
    Publication date: July 31, 2003
    Inventors: Alexander Flohr, Roland Jakob-Roetne, Roger David Norcross, Claus Riemer
  • Pyridone substituted benzothiazole derivatives
    Patent number: 6599901
    Abstract: The present invention relates to compounds of the formula wherein R is as defined herewithin. The compounds of formula I have a good affinity to the A2A receptor and therefore they may be used in the control or prevention of illnesses based on the modulation of the adenosine system, such as Alzheimer's disease, Parkinson's disease, Huntington's disease, neuroprotection, schizophrenia, anxiety, pain, respiration deficits, depression, drug addiction, such as amphetamine, cocaine, opioids, ethanol, nicotine, cannabinoids, or against asthma, allergic responses, hypoxia, ischaemia, seizure and substance abuse. Furthermore, compounds of the present invention may be useful as sedatives, muscle relaxants, antipsychotics, antiepileptics, aniticonvulsants and cardiaprotective agents for disorders such as coronary artery disease and heart failure.
    Type: Grant
    Filed: November 5, 2002
    Date of Patent: July 29, 2003
    Assignee: Hoffman-La Roche Inc.
    Inventors: Alexander Flohr, Roland Jakob-Roetne, Roger David Norcross, Claus Riemer
  • 7-Morpholin-4yl-benzothiazole amide derivatives
    Patent number: 6596718
    Abstract: A compound of the formula A compound of formula I has a good affinity to the A2A receptor and is useful for the treatment of diseases mediated by this receptor.
    Type: Grant
    Filed: November 18, 2002
    Date of Patent: July 22, 2003
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Alexander Flohr, Roland Jakob-Roetne, Norcross David Roger, Claus Riemer
  • Isonicotin- and nicotinamide derivatives of benzothiazoles
    Publication number: 20030134854
    Abstract: The present invention relates to compounds of the formula 1
    Type: Application
    Filed: November 5, 2002
    Publication date: July 17, 2003
    Inventors: Alexander Flohr, Roland Jakob-Roetne, Roger David Norcross, Claus Riemer
  • BENZOTHIAZOLE DERIVATIVES
    Publication number: 20030134855
    Abstract: The present invention relates to compounds of the formula 1
    Type: Application
    Filed: November 15, 2002
    Publication date: July 17, 2003
    Inventors: Alexander Flohr, Roland Jakob-Roetne, Roger David Norcross, Claus Riemer