Abstract: The present invention concerns an image conversion module (09) that comprises an optical interface (10) for establishing an optical path (07). The image conversion module (09) further comprises a beam splitting element (13) on the optical path (07). The beam splitting element (13) is configured for splitting a beam entering the optical interface (10, 11) on the optical path (07) into a first optical subpath (14) and a second optical subpath (16). The image conversion module (09) further comprises a microelectromechanical optical system (17) that is configured for enhancing a depth of field on the first optical subpath (14) that is directed to a first optoelectronic submodule (21). The image conversion module (09) further comprises a second optoelectronic submodule (24) having an electronic sensor (26) on the second optical subpath (16). The second optoelectronic submodule (24) is configured for acquiring additional data on the sample (02).

Abstract: The invention concerns a method for capturing and displaying microscopic images of a sample to be microscopically examined using a digital microscope. In a step, a sequence of microscopic images with enhanced visual information in a third geometric dimension is captured. The sequence of the microscopic images is displayed while it is captured. A visual representation of a capturing range in the third geometric dimension is displayed at a graphical user interface. A user input that defines at least one adjustment of the capturing range is received resulting in an adjusted capturing range. At least one parameter of detecting visual information in the third geometric dimension is adjusted according to the adjusted capturing range. It is continued to capture the sequence of the microscopic images with the enhanced visual information in the third geometric dimension applying the at least one adjusted parameter. Furthermore, the invention concerns a digital microscope.

Abstract: The present invention concerns a method for producing a microscopic image with an extended depth of field by means of a microscope. The microscope comprises an images sensor that comprises pixels that are arranged as a matrix that is formed by lines. In a step of the method, a plurality of microscopic frames of a specimen is acquired while a focus position (z) is changed. The microscopic frames are acquired line by line. The focus position (z) is changed over a course of acquiring individuals of the microscopic frames. In a further step, parts of individuals of the acquired lines are identified. These parts sharply image the specimen. The identified parts of the lines are composed in order to form a microscopic image of the specimen with an extended depth of field. Furthermore, the present invention concerns a microscope.

Abstract: The invention relates first to a camera module for a microscope. The camera module comprises an optical interface for inserting the camera module into an imaging beam path of the microscope, which imaging beam path images a nominal intermediate image. Furthermore, the camera module comprises an electronic image converter and a functional element for changing an intermediate image plane, which functional element is arranged in a beam path of the camera module between the optical interface and the image converter. The camera module also comprises a first optical assembly having an optical power, which first optical assembly is arranged in the beam path between the optical interface and the image converter. According to the invention, a distance between the functional element and the optical interface along the beam path or a distance between the first optical assembly and the optical interface along the beam path can be changed. The invention further relates to a method for operating the camera module.

Abstract: The present invention relates to a method for viewing a specimen using a microscope which comprises an objective lens and an image sensor for converting an image formed on the image sensor by the objective lens. A field of view of the microscope can be varied by selecting a section of the image sensor. In one step of the method, an initial image of at least a partial section of the specimen is captured with the microscope, for which a first field of view is selected on the microscope. The initial image is analyzed to determine at least two differing fields of view forming a partial area image, wherein a partial area of the initial image is formed by each of the fields of view forming a partial area image. Images of the partial areas of the specimen are captured for each of the determined fields of view forming a partial area image. The invention further relates to a microscope for viewing a specimen using a microscope.

Abstract: The invention concerns a digital microscope for capturing images of a sample with an extended depth of field. The microscope comprises a stand (01) with an opening (16) for receiving an optical unit (07). The microscope further comprises an optical unit (07) with an objective (08), an image sensor, and a microelectromechanical optical system on an optical path from the objective (08) to the image sensor. The microelectromechanical optical system is configured for extending a depth of field at the optical path. According to the invention, the imaging unit (07) comprises a mounting unit (13) comprising a first portion (14) for removable mounting the mounting unit (13) into the opening (16) of the stand (01), a second portion (18) for removable mounting an illumination unit (17) onto the mounting unit (13), and a third portion (21) for removable mounting an additional lens (19) onto the mounting unit (13) into an optical axis (22) of the objective (08). Furthermore, the invention concerns a microscopic set.

Abstract: An object is arranged in a measurement region at an objective. In addition, an imaging arrangement which comprises the objective or is connected thereto by means of an objective holder is configured to image light emanating from the object for a plurality of object planes with respect to the object to form a wide-field intermediate image, wherein by means of a longitudinal chromatic aberration of the imaging arrangement the object planes are staggered depending on a wavelength of the light from the object along a depth axis. Moreover, an image capturing device is configured to capture the wide-field intermediate image in an imaging manner and in a manner resolved with respect to one or a plurality of selectable spectral components, each corresponding to one of the object planes.

Abstract: The present invention concerns an image conversion module (09) that comprises an optical interface (10) for establishing an optical path (07). The image conversion module (09) further comprises a beam splitting element (13) on the optical path (07). The beam splitting element (13) is configured for splitting a beam entering the optical interface (10) on the optical path (07) into a first optical subpath (14) and a second optical subpath (16). The image conversion module (09) further comprises a microelectromechanical optical system (17) that is configured for enhancing a depth of field on the first optical subpath (14) that is directed to a first optoelectronic submodule (21), which comprises an image sensor (22). The image conversion module (09) further comprises a second optoelectronic submodule (24) that comprises an electronic sensor (26) on the second optical subpath (16). The second optoelectronic submodule (24) is configured for acquiring additional data on the sample (02).

Abstract: A device for recording images is provided, an image-recording device and an illumination device being arranged on the same side of a specimen plane in said device. The image-recording device has illumination portions, for example individual light sources, which are actuatable independently of one another in order to be able to illuminate a specimen in the specimen plane at different angles and/or from different directions. In this way, it is possible to record a plurality of images with different illuminations, which can be combined to form a results image with improved properties.

Abstract: The invention relates first to a camera module for a microscope. The camera module comprises an optical interface for inserting the camera module into an imaging beam path of the microscope, which imaging beam path images a nominal intermediate image. Furthermore, the camera module comprises an electronic image converter and a functional element for changing an intermediate image plane, which functional element is arranged in a beam path of the camera module between the optical interface and the image converter. The camera module also comprises a first optical assembly having an optical power, which first optical assembly is arranged in the beam path between the optical interface and the image converter. According to the invention, a distance between the functional element and the optical interface along the beam path or a distance between the first optical assembly and the optical interface along the beam path can be changed. The invention further relates to a method for operating the camera module.

Abstract: The present invention relates to a microscope assembly for the three-dimensional capture of a sample to be microscopically examined and for the display of three-dimensional images of the sample under the microscope. The microscope assembly comprises an image capture unit for obtaining photographs of the sample and an image processing unit for generating three-dimensional images of the sample from the photographs of the image capture unit. In addition, the microscope assembly comprises at least one display unit for the three-dimensional display of the generated threedimensional images of the sample. According to the invention, the microscope assembly for generating and displaying the three-dimensional images of the sample is configured with an image refresh rate of at least 1 frame per second.

Abstract: The invention concerns a functional module (02) for a microscope. That functional module (02) comprises a mechanical interface (11) for removable mounting the functional module (02) to a module support of the microscope. The functional module (02) further comprises an optical interface (12) for establishing an optical path (09) from an objective (03) of the microscope to the functional module (02). Furthermore, the functional module (02) comprises at least one image sensor (21). The functional module (02) comprises a first and a second microelectromechanical optical system (17, 18). The first microelectromechanical optical system (17) is configured for enhancing a depth of field on a first optical subpath (14) that is directed to the image sensor (21). The second microelectromechanical optical system (18) is configured for enhancing a depth of field on a second optical subpath (16) that is directed to the image sensor (21). The invention further concerns a microscope.

Abstract: The present invention relates firstly to a method for acquiring a stack of microscopic images of a specimen. The microscopic images of the stack are acquired from different focus positions. According to the invention, a plurality of the microscopic images of the specimen are respectively acquired from at least some of the focus positions using different settings of an illumination unit for illuminating the specimen. According to the invention, the illumination settings with which the microscopic images of the specimen are acquired is decided upon individually in each case at least for several of the focus positions. The invention further relates to a digital microscope for microimaging a specimen.

Abstract: The present invention relates to a digital microscope that includes an objective lens for enlarged optical imaging of a sample in an image plane. An image with an optical resolution may be represented in the image plane by means of the objective lens. The microscope also includes an image sensor for converting the image, depicted on the image sensor by the objective lens, into an electrical signal. The image sensor includes a matrix of pixels by means of which a maximum image resolution of the image sensor is determined, which is finer than the optical resolution of the objective lens. The objective lens has a maximum magnification factor of at most 40. The optical resolution of the objective lens is defined as a minimum distance between two structures that are distinguishable in the image. The maximum image resolution of the image sensor is defined by a pixel pitch.

Abstract: A method for correcting colors of a color reproduction of a digital microscope and a digital microscope are described. In a first step of a method according to the invention, a color image of a sample that is to be examined under the microscope is recorded. When the recording is performed, wavelength-dependent properties of a microscope illumination unit that illuminates the sample are determined in order to describe a state of the microscope illumination unit, in that settings selected at the microscope illumination unit are captured. A set of correction values is determined, which is associated with a state of the microscope illumination unit that is selected in accordance with the state of the microscope illumination unit determined when the recording is performed. In a further step, the colors of the recorded color image of the sample are corrected by applying the correction values of the previously determined set.

Abstract: The present invention relates to an image conversion module for a microscope, the image conversion module being designed to convert images using an additional function. Said image conversion module initially comprises at least one functional element for implementing the additional function which is used for recording an extended depth of focus, for producing an optical zoom, for measuring spectral properties, the measuring color, for measuring polarization, for measuring wave fronts for measuring material properties and/or for aberration correction. Other components of the image conversion module are at least one image sensor, an optical interface which can be optically coupled to a lens of the microscope, a data interface for transmitting the data provided by the image sensor, and a mechanical interface for mechanically placing the image conversion module on the microscope. The invention also relates to a microscope comprising said type of image conversion module.

Abstract: The present invention relates to a method for viewing a specimen using a microscope which comprises an objective lens and an image sensor for converting an image formed on the image sensor by the objective lens. A field of view of the microscope can be varied by selecting a section of the image sensor. In one step of the method, an initial image of at least a partial section of the specimen is captured with the microscope, for which a first field of view is selected on the microscope. The initial image is analyzed to determine at least two differing fields of view forming a partial area image, wherein a partial area of the initial image is formed by each of the fields of view forming a partial area image. Images of the partial areas of the specimen are captured for each of the determined fields of view forming a partial area image. The invention further relates to a microscope for viewing a specimen using a microscope.

Abstract: The present invention relates to a method for generating a three-dimensional model of a sample (09) using a microscope (01), comprising the following steps: specifying a perspective for recording images of at least one area of the sample (09), wherein the perspective is specified by the angle and the position of the optical axis of the objective lens relative to a sample, and by the angular distribution of illumination radiation relative to the sample; recording multiple individual images of the sample (09) at various focus positions from the specified perspective; repeating the preceding steps for the at least one area of the sample (09) with at least one other different perspective; computing a three-dimensional model of the area of the sample (09) from the recorded individual images of the area of the sample (09). The invention further relates to a digital microscope that is configured for carrying out the method according to the invention.

Abstract: The present invention relates to a digital microscope that includes an objective lens for enlarged optical imaging of a sample in an image plane. An image with an optical resolution may be represented in the image plane by means of the objective lens. The microscope also includes an image sensor for converting the image, depicted on the image sensor by the objective lens, into an electrical signal. The image sensor includes a matrix of pixels by means of which a maximum image resolution of the image sensor is determined, which is finer than the optical resolution of the objective lens. The objective lens has a maximum magnification factor of at most 40. The optical resolution of the objective lens is defined as a minimum distance between two structures that are distinguishable in the image. The maximum image resolution of the image sensor is defined by a pixel pitch.

Abstract: The present invention relates firstly to a method for producing a microscopic image with an extended depth of field by means of a microscope. In a step of the method, a plurality of microscopic frames of a specimen are acquired from different focus positions, for example with different dimensions of a distance between the specimen and an objective lens of the microscope. In another step, the plurality of microscopic frames are processed so as to form a microscopic image with an extended depth of field. According to the invention, the focus position is continuously changed during the acquisition of at least some of the microscopic frames at a variable speed or with variable acceleration. The invention further relates to a microscope with an objective lens for optically imaging a specimen.