Patents by Inventor Alexander H. Siemons
Alexander H. Siemons has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240058129Abstract: A medical balloon sensing assembly constituted of: a handle; a first catheter extending distally from the handle; an inflatable medical balloon, the inflatable medical balloon secured by the first catheter; at least one sensor position member; and at least one sensor secured to the at least one sensor position member, wherein the at least one sensor position member is arranged to contact an outer face of the inflatable medical balloon.Type: ApplicationFiled: February 21, 2023Publication date: February 22, 2024Inventors: Shaun Fetherston, Alexander H. Siemons, Blake W. Axelrod, Gil Senesh, Tomer Saar, Oren Cohen, Elazar Levi Schwarcz, Tamir S. Levi, Michael Bukin, Michael R. Bialas, Timothy A. Geiser, Sudarsan Pranatharthikaran, Carla Susana Cerqueira
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Publication number: 20230248249Abstract: An implantable sensor device includes a sensor-support substrate, a microelectromechanical systems (MEMS) pressure sensor device mounted to the sensor-support substrate, a transduction medium applied over the pressure sensor device, and a biocompatibility layer applied over the transduction mediumType: ApplicationFiled: February 24, 2023Publication date: August 10, 2023Inventors: Yaron Keidar, Mark Simon Vreeke, Ming H. Wu, Alexander H. Siemons
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Publication number: 20230218180Abstract: A prosthetic valve comprises a frame assembly having a first opening at an inflow portion of the frame assembly and a second opening at an outflow portion of the frame assembly, a first sensor device situated at the inflow portion of the frame, and a second sensor device situated at the outflow portion of the frame. Each of the first sensor device and the second sensor device is configured to sense a physical parameter and provide a sensor signal. The prosthetic valve further comprises a transmitter assembly configured to receive the sensor signals from the first sensor device and the second sensor device and wirelessly transmit a transmission signal based at least in part on the sensor signals.Type: ApplicationFiled: February 24, 2023Publication date: July 13, 2023Inventors: Muhammad Mujeeb-U-Rahman, Alexander H. Siemons, Rendle Lamarr Myles, JR.
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Publication number: 20230210496Abstract: A biomedical sensor is provided that includes a deformable body panel, a first ultrasonic transducer, a second ultrasonic transducer, and a displacement sensor. The first and second ultrasonic transducers are attached to, and the displacement sensor is in communication with, the deformable body panel. The biomedical sensor is disposable in at least one default configuration wherein the first and second ultrasonic transducers are disposed relative to one another in a known first spatial transducer configuration. The biomedical sensor is disposable in one or more deformed configurations wherein the first and second ultrasonic transducers are disposed relative to one another in a second spatial transducer configuration different than the first spatial transducer configuration. The at least one displacement sensor is configured to produce signal information indicative of a difference between the first and second spatial transducer configurations.Type: ApplicationFiled: March 9, 2023Publication date: July 6, 2023Inventors: Julio Agustin Isla Garcia, Rendle Lamarr Myles, JR., Xiaolong Li, Alexander H. Siemons, Blake W. Axelrod
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Publication number: 20230148992Abstract: A system and method for non-invasively sensing a blood vessel are provided. The system includes a sensor and a controller. The sensor has an array of ultrasound transducers that includes at least a first ultrasound transducer and a second ultrasound transducer. The controller is in communication with the first ultrasound transducer and the second ultrasound transducer, and a memory storing instructions. The instructions when executed cause the controller to: a) control the first ultrasound transducer to produce a first ultrasonic beam, to receive reflected first ultrasonic signals, and to communicate first sensed signals to the controller; b) control the second ultrasound transducer to produce a second ultrasonic beam, to receive reflected second ultrasonic signals, and to communicate second sensed signals to the controller; c) determine a first vessel diameter value; d) determine a second vessel diameter value; and e) determine a pulse wave velocity value.Type: ApplicationFiled: January 20, 2023Publication date: May 18, 2023Inventors: Julio Agustin Isla Garcia, Xiaolong Li, Rendle Lamarr Myles, JR., Alexander H. Siemons
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Publication number: 20230068893Abstract: Sensor-integrated prosthetic valves that can comprise a variety of features, including a plurality of valve leaflets, a frame assembly configured to support the plurality of valve leaflets and define a plurality of commissure supports terminating at an outflow end of the prosthetic valve, a sensor device associated with the frame assembly and configured to generate a sensor signal, for example, a sensor signal indicating deflection of one or more of the plurality of commissure supports, and a transmitter assembly configured to receive the sensor signal from the sensor device and wirelessly transmit a transmission signal that is based at least in part on the sensor signal.Type: ApplicationFiled: October 13, 2022Publication date: March 2, 2023Inventors: Salvador Marquez, Da-Yu Chang, Cindy Woo, Hao-Chung Yang, Lynn T. Dang, Javier A. Sanguinetti, Alexander H. Siemons, Yaron Keidar, Virginia Qi Lin, Brian S. Conklin, Donald E. Bobo, Jr.
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Patent number: 11471275Abstract: Sensor-integrated prosthetic valves that can comprise a variety of features, including a plurality of valve leaflets, a frame assembly configured to support the plurality of valve leaflets and define a plurality of commissure supports terminating at an outflow end of the prosthetic valve, a sensor device associated with the frame assembly and configured to generate a sensor signal, for example, a sensor signal indicating deflection of one or more of the plurality of commissure supports, and a transmitter assembly configured to receive the sensor signal from the sensor device and wirelessly transmit a transmission signal that is based at least in part on the sensor signal.Type: GrantFiled: May 29, 2020Date of Patent: October 18, 2022Assignee: Edwards Lifesciences CorporationInventors: Salvador Marquez, Da-Yu Chang, Cindy Woo, Hao-Chung Yang, Lynn T. Dang, Javier A. Sanguinetti, Alexander H. Siemons, Yaron Keidar, Virginia Qi Lin, Brian S. Conklin, Donald E. Bobo, Jr.
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Patent number: 11357416Abstract: Disclosed is a system to provide adaptive tuning through a control system to a finger cuff connectable to a patient's finger to be used in measuring the patient's blood pressure in the patient's artery by a blood pressure measurement system utilizing a volume clamp method. When the finger cuff is placed around the patient's finger, the bladder and the LED-PD pair aid in measuring the patient's blood pressure by the blood pressure measurement system utilizing the volume clamp method, wherein the adaptive tuning system: applies a first pressure impulse and measures a pleth versus time response; from the pressure versus time response, determines pleth servo gains that compensate for delays in a pleth response of the finger; and uses the determined pleth servo gains in the control system in measuring the patient's blood pressure by the blood pressure measurement system utilizing the volume clamp method.Type: GrantFiled: February 4, 2019Date of Patent: June 14, 2022Assignee: Edwards Lifesciences CorporationInventors: Blake W. Axelrod, Alexander H. Siemons
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Patent number: 11089971Abstract: Apparatus and methods for the measurement, control, or both, of thermodilution injectate flow for calculation of transpulmonary thermodilution parameters. An injectate delivery system includes a syringe for holding an injectate and a conduit configured at one end to be connected to a catheter. A flow measurement device is interposed in the conduit to generate a signal for determining the flow rate of the fluid from the syringe to the catheter. A processor receives the signal from the flow measurement device and calculates the injectate volume to be used as input for calculating a transpulmonary thermodilution parameter such as cardiac output. A GUI is provided to direct a user on whether the injection rate is too fast or too slow. Rather than measuring or calculating flow rate, a system may include a constant flow valve to provide a constant flow rate from the syringe.Type: GrantFiled: October 21, 2015Date of Patent: August 17, 2021Assignee: Edwards Lifesciences CorporationInventors: Alexander H. Siemons, Wei-Jiun Liu
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Publication number: 20200289257Abstract: Sensor-integrated prosthetic valves that can comprise a variety of features, including a plurality of valve leaflets, a frame assembly configured to support the plurality of valve leaflets and define a plurality of commissure supports terminating at an outflow end of the prosthetic valve, a sensor device associated with the frame assembly and configured to generate a sensor signal, for example, a sensor signal indicating deflection of one or more of the plurality of commissure supports, and a transmitter assembly configured to receive the sensor signal from the sensor device and wirelessly transmit a transmission signal that is based at least in part on the sensor signal.Type: ApplicationFiled: May 29, 2020Publication date: September 17, 2020Inventors: Salvador Marquez, Da-Yu Chang, Cindy Woo, Hao-Chung Yang, Lynn T. Dang, Javier A. Sanguinetti, Alexander H. Siemons, Yaron Keidar, Virginia Qi Lin, Brian S. Conklin, Donald E. Bobo, JR.
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Patent number: 10667904Abstract: Sensor-integrated prosthetic valves that can comprise a variety of features, including a plurality of valve leaflets, a frame assembly configured to support the plurality of valve leaflets and define a plurality of commissure supports terminating at an outflow end of the prosthetic valve, a sensor device associated with the frame assembly and configured to generate a sensor signal, for example, a sensor signal indicating deflection of one or more of the plurality of commissure supports, and a transmitter assembly configured to receive the sensor signal from the sensor device and wirelessly transmit a transmission signal that is based at least in part on the sensor signal.Type: GrantFiled: March 7, 2017Date of Patent: June 2, 2020Assignee: Edwards Lifesciences CorporationInventors: Salvador Marquez, Da-Yu Chang, Cindy Woo, Hao-Chung Yang, Lynn T. Dang, Javier A. Sanguinetti, Alexander H. Siemons, Yaron Keidar, Virginia Qi Lin, Brian S. Conklin, Donald E. Bobo, Jr.
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Publication number: 20190261872Abstract: Disclosed is a system to provide adaptive tuning through a control system to a finger cuff connectable to a patient's finger to be used in measuring the patient's blood pressure in the patient's artery by a blood pressure measurement system utilizing a volume clamp method. When the finger cuff is placed around the patient's finger, the bladder and the LED-PD pair aid in measuring the patient's blood pressure by the blood pressure measurement system utilizing the volume clamp method, wherein the adaptive tuning system: applies a first pressure impulse and measures a pleth versus time response; from the pressure versus time response, determines pleth servo gains that compensate for delays in a pleth response of the finger; and uses the determined pleth servo gains in the control system in measuring the patient's blood pressure by the blood pressure measurement system utilizing the volume clamp method.Type: ApplicationFiled: February 4, 2019Publication date: August 29, 2019Inventors: Blake W. Axelrod, Alexander H. Siemons
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Publication number: 20190167195Abstract: Disclosed is a system to monitor a finger cuff connectable to a patient's finger to be used in measuring the patient's blood pressure by a blood pressure measurement system utilizing the volume clamp method and to measure the plethysmogram of the finger cuff. The system comprises the finger cuff that includes an enclosing portion that encloses a patient's finger. The enclosing portion includes a bladder and a light emitting diode (LED) and photodiode (PD) pair. The system further comprises a processor to: command applying pneumatic pressure to the bladder of the finger cuff from a low pressure to a high pressure; measure the plethysmogram of the finger cuff as the pressure increases from the low pressure to the high pressure; and determine fitness of the finger cuff on the patient's finger based on the measured plethysmogram. When the finger cuff is placed around the patient's finger, the bladder and the LED-PD pair aid the processor in measuring the plethysmogram.Type: ApplicationFiled: November 2, 2018Publication date: June 6, 2019Inventors: Blake W. Axelrod, Alexander H. Siemons, Virginia Qi Lin, Leah Paige Gaffney, Laura J. Livant
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Publication number: 20190133460Abstract: Disclosed is an integrated blood sampling-pressure monitoring system to sample blood from a patient and to measure the blood pressure of the patient. The integrated blood sampling-pressure monitoring system may include: a pressure transducer to measure the blood pressure of the patient; a blood sampling portion to sample blood from the patient; and a restrictor. The restrictor may be interposed between the pressure transducer and the blood sampling portion, such that, the pressure transducer may be located closer to the patient than the blood sampling portion along a fluid line when the blood sampling-pressure monitoring system is connected to the patient.Type: ApplicationFiled: October 30, 2018Publication date: May 9, 2019Inventors: Jason A. Wine, Alexander H. Siemons, Siddarth Kamath Shevgoor
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Publication number: 20190133532Abstract: Disclosed is a method for filtering a distorted pressure transducer signal from a pressure transducer in a blood pressure monitoring system, comprising: determining one or more pressure transducer signal filtering parameters; receiving a distorted pressure transducer signal from the pressure transducer; filtering the distorted pressure transducer signal to generate a corrected pressure transducer signal based on the one or more pressure transducer signal filtering parameters; and outputting the corrected pressure transducer signal to a patient monitor.Type: ApplicationFiled: October 30, 2018Publication date: May 9, 2019Inventors: Jason A. Wine, Alexander H. Siemons, Siddarth Kamath Shevgoor
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Publication number: 20190125232Abstract: Disclosed is a multi-port control valve with multi-lumen paths diverging flow so that, the multi-port control valve fills and expels fluid at the same time through the same port for use in a blood sampling, blood pressure monitoring system that includes a sampling site, a pressure transducer, and reservoir. The multi-port control valve may include a rotatable valve member and three ports. Each of the three ports is connected to one of the sampling site, the pressure transducer, and the reservoir. In particular, the rotatable valve member is rotatable, such that, depending upon a position of the rotatable valve member, one of the three ports is blocked from fluid communication with the other two ports.Type: ApplicationFiled: November 1, 2017Publication date: May 2, 2019Applicant: Edwards Lifesciences CorporationInventors: Jason A. Wine, Alexander H. Siemons, Andrew Nguyen Hoan, Mandana Farhadieh, Brian Patrick Murphy
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Publication number: 20180325396Abstract: Disclosed is a connector for a blood pressure measurement system that includes a pressure generating and regulating system and a finger cuff, in which the connector comprises: a first half portion pneumatically and electrically connected to the pressure generating and regulating system; and a second half portion fixedly attached to the finger cuff, wherein the first half portion and the second half portion are connectable in two or more orientations, and wherein the pressure generating and regulating system and the finger cuff are pneumatically and electrically connected when the first half portion and the second half portion are connected.Type: ApplicationFiled: April 18, 2018Publication date: November 15, 2018Inventors: Blake W. Axelrod, Alexander H. Siemons
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Publication number: 20180289271Abstract: Disclosed is a blood pressure measurement device that utilizing volume clamping and that is wearable by a patient. The blood pressure measurement device may comprise: a finger cuff attachable to the patient's finger including a light emitting diode (LED)-photodiode (PD) pair to measure a pleth signal and a bladder surrounding the finger and a blood pressure measurement controller coupled to the bladder through a finger cuff connector to provide pneumatic pressure to the bladder. The blood pressure measurement controller may be wearable by the patient. The blood pressure measurement controller may include: a pump coupled to the finger cuff connector, a valve, a pressure sensor, and control circuitry coupled to the pump, the valve, the pressure sensor, and the LED-PD pair.Type: ApplicationFiled: January 24, 2018Publication date: October 11, 2018Applicant: Edwards Lifesciences CorporationInventors: Blake W. Axelrod, Alexander H. Siemons
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Publication number: 20170265756Abstract: Apparatus and methods for the measurement, control, or both, of thermodilution injectate flow for calculation of transpulmonary thermodilution parameters. An injectate delivery system includes a syringe for holding an injectate and a conduit configured at one end to be connected to a catheter. A flow measurement device is interposed in the conduit to generate a signal for determining the flow rate of the fluid from the syringe to the catheter. A processor receives the signal from the flow measurement device and calculates the injectate volume to be used as input for calculating a transpulmonary thermodilution parameter such as cardiac output. A GUI is provided to direct a user on whether the injection rate is too fast or too slow. Rather than measuring or calculating flow rate, a system may include a constant flow valve to provide a constant flow rate from the syringe.Type: ApplicationFiled: October 21, 2015Publication date: September 21, 2017Applicant: Edwards Lifesciences CorporationInventors: Alexander H. Siemons, Wei-Jiun Liu
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Publication number: 20170265757Abstract: An integrated pressure sensing device is disclosed. Embodiments of the disclosed concepts provide a device that integrates hemodynamic pressure transducers or sensors into a single package. The package can be designed for precordial placement on the subject so that pressure readings are substantially accurate and appropriately calibrated without “leveling” the sensors relative to a subject's heart using a separate support, and regardless of the subject's position. A lumen set can be configured to maintain a fluid column between each pressure transducer and the subject's blood stream and in some embodiments, the assembly, including all transducers, can be fed from a single fluid source such as a single IV bag.Type: ApplicationFiled: October 23, 2015Publication date: September 21, 2017Applicant: Edwards Lifesciences CorporationInventors: Alexander H. Siemons, Steven E. Backer