Abstract: Methods and systems for reduced file transfer protocols are disclosed, Provided are methods and systems for implementation for securing software updates to satellites and remote locations under power, bandwidth, or frequency limitations, using cryptographic protocols for different components of a delivery architecture for a large data payload, such as for a software update, from a trusted, back-end (terrestrial) source to receivers: a low-response protocol for initial transmission and confirmation (BAC protocol), and two possible inter-unit distribution protocols (COCO-SYNC-R protocol (Pull) or COCO-SYNC-P (PUSH)) with differing optimizations based on connectivity scenarios. These protocols introduce a means for accounting for both security (authentication) and efficacy (minimized RF footprint) in the delivery of critical data payloads to remote receivers.

Abstract: A novel gRNA-ligand binding complex is provided. This complex may be used to bring Type V Cas proteins and additional effectors to DNA for base editing. The design of the systems allows for the production of efficient modular components that provide flexibility when editing DNA.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for presence determination. Systems can include one or more user devices and terminal devices. A current location may be determined of a user that is associated with a particular space of a plurality of different spaces. A plurality of location results may be calculated, wherein each location result is computed using a distinct process of a plurality of processes; and evaluating the plurality of location results to determine a current space of the user; wherein the determining is performed by one or more of, a particular user device, a terminal device, or a server system.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for presence determination. Systems can include one or more user devices and terminal devices. A current location may be determined of a user that is associated with a particular space of a plurality of different spaces. A plurality of location results may be calculated, wherein each location result is computed using a distinct process of a plurality of processes; and evaluating the plurality of location results to determine a current space of the user; wherein the determining is performed by one or more of, a particular user device, a terminal device, or a server system.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for presence determination. One of the methods includes for one or more user devices having one or more associated users, determining a current location of a user, wherein the current location is associated with a particular space of a plurality of different spaces, wherein the determining includes: computing a plurality of location results, wherein each location result is computed using a distinct process of a plurality of processes; and evaluating the plurality of location results to determine a current space of the user; wherein the determining is performed by one or more of, a particular user device, a terminal device, or a server system.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for presence determination. One of the methods includes for one or more user devices having one or more associated users, determining a current location of a user, wherein the current location is associated with a particular space of a plurality of different spaces, wherein the determining includes: computing a plurality of location results, wherein each location result is computed using a distinct process of a plurality of processes; and evaluating the plurality of location results to determine a current space of the user; wherein the determining is performed by one or more of, a particular user device, a terminal device, or a server system.

Abstract: A method of changing an association of a remote control device from a first electronic device to a second electronic device is presented. In the method, a command for an electronic device is generated and transmitted by the remote control device. At this point, the remote control device is associated with the first electronic device to control the first electronic device, and the remote control device is not associated with the second electronic device. If an acknowledgment of the command is not received, a request to associate the remote control device with another electronic device is transmitted. A reply to the request is then received from the second electronic device. In response to the reply, the remote control device is disassociated from the first electronic device and associated with the second electronic device.

Abstract: A method of changing an association of a remote control device from a first electronic device to a second electronic device is presented. In the method, a command for an electronic device is generated and transmitted by the remote control device. At this point, the remote control device is associated with the first electronic device to control the first electronic device, and the remote control device is not associated with the second electronic device. If an acknowledgment of the command is not received, a request to associate the remote control device with another electronic device is transmitted. A reply to the request is then received from the second electronic device. In response to the reply, the remote control device is disassociated from the first electronic device and associated with the second electronic device.