Abstract: The invention relates to a device (10; 210; 310; 410; 510) for tomographic image recording. The device comprises a sample retainer (14), a light source (12), and a detector unit (16). The light source (12) is designed to produce a pencil beam (38), which has a beam direction (40) and which passes through a sample volume of the sample retainer (14) provided in order to accommodate a sample, and has an optical control element (30), which is able to move the pencil beam (38) passing through the sample retainer (14) transversely to the beam direction (40) while the beam direction (40) remains substantially unchanged. The detector unit (16) is designed to detect at least a portion of scattered radiation (64; 64?) escaping from a section of the pencil beam (38) within the sample volume or the sample retainer (14) in a non-spatially-resolved manner.

Abstract: The invention provides a device and a method for flow cytometric fractionation of particles contained in a fluid stream, wherein sections of the fluid stream, especially droplets if the fluid stream is a droplet stream, are irradiated with a laser. The laser disposed for the irradiation of the sections of the fluid stream can have a wavelength which is absorbed by the fluid and can have a sufficient radiation duration and radiation intensity to deflect sections of the fluid stream.

Abstract: The invention relates to a device (10; 210; 310; 410; 510) for tomographic image recording. The device comprises a sample retainer (14), a light source (12), and a detector unit (16). The light source (12) is designed to produce a pencil beam (38), which has a beam direction (40) and which passes through a sample volume of the sample retainer (14) provided in order to accommodate a sample, and has an optical control element (30), which is able to move the pencil beam (38) passing through the sample retainer (14) transversely to the beam direction (40) while the beam direction (40) remains substantially unchanged. The detector unit (16) is designed to detect at least a portion of scattered radiation (64; 64?) escaping from a section of the pencil beam (38) within the sample volume or the sample retainer (14) in a non-spatially-resolved manner.

Abstract: The invention provides a device and a method for flow cytometric fractionation of particles contained in a fluid stream, wherein sections of the fluid stream, especially droplets if the fluid stream is a droplet stream, are irradiated with a laser. The laser disposed for the irradiation of the sections of the fluid stream can have a wavelength which is absorbed by the fluid and can have a sufficient radiation duration and radiation intensity to deflect sections of the fluid stream.

Abstract: The invention is directed to a method for the manipulation of at least one cell, the method comprising the steps of depositing a metal onto the surface of a substrate, placing the at least one cell at or near the surface of the substrate, and irradiating the surface of the substrate with at least one laser pulse. The inventive method is characterized by the formation of surface structures with a size of one micrometer or less on the surface of the substrate prior to depositing the metal thereon. The invention is also directed to a system for the manipulation of at least one cell, the system comprising a substrate with surface structures having a size of 1 micrometer or less, wherein a metal is deposited on the surface structures, and wherein the system further comprises a laser for irradiating the surface structures.

Abstract: A device for machining a material with ultrashort laser pulses is described. This device comprises: (a) a device (1) for generating a sequence of first laser pulses, where the first laser pulses each have a duration of less than 300 picoseconds and the repetition rate for the first laser pulses is in the range between 100 kHz and 1 GHz, (b) a converter (2) for converting a first set of the sequence of first laser pulses into a sequence of second laser pulses for application to and for machining of the material, where the second laser pulses each have a duration of less than 300 picoseconds and the repetition rate for the second laser pulses is in the range between 1 Hz and 1 MHz, as well as (c) a testing device (3, 5, 6, 7, 15) that is equipped to apply first laser pulses, which do not belong to the first set, to the material, to detect specific results of this application and to provide these detected results as information.

Abstract: A device for machining a material with ultrashort laser pulses is described.