Abstract: A system (1) for additive manufacturing of three-dimensional objects, comprising one or more working stations (21), which are provided for performing at least one working process in the additive manufacturing of three-dimensional objects, at least one freely positionable mobile storage unit (2) comprising a rack-like storage device (4) comprising at least one storage room (5) provided for storing at least one powder module (6), especially for the purpose of conveying the powder module (6) between different working stations (21) of the system (1), and at least one driverless, freely movable mobile conveying unit (3) comprising a receiving device (12) provided for receiving at least one mobile storage unit (2) for the purpose of conveying the storage unit (2) between different working stations (21) of the system (1).

Abstract: The present invention refers to a set for the production of a ready-to-use chemo-therapeutic composition for intraperitoneal administration as an aerosol, wherein the set comprises an aqueous concentrate containing at least cisplatin in a first predetermined concentration and doxorubicin in a second predetermined concentration with a predetermined ratio of the first and the second concentration and having a pH value in the range from 3.0 to 7.0. The set further comprises a physiological aqueous carrier solution, which is for optional dilution of the concentrate depending on target concentrations of cisplatin and doxorubicin in the chemo-therapeutic composition to be applied. Further, the invention refers to a method for providing of a ready-for-use chemotherapeutic composition for intraperitoneal administration as an aerosol by using of a set, to a chemotherapeutic composition for intraperitoneal administration as an aerosol, and a use of the chemotherapeutic composition.

Abstract: The present invention relates to a medical instrument for the targeted introduction of a substance into a body cavity and to a tool (1) therefor. According to the invention, the tool (1) has a shaft (2) with a lumen (6), on the distal end (1?) of which is situated a nozzle head (3) with at least two nozzles (4), wherein the nozzles (4) are spaced from each other at an angle of less than 180° and equally relative to a centre axis (M) of the shaft (2).

Abstract: The present invention relates to a medical instrument for the targeted introduction of a substance into a body cavity and to a tool (1) therefor. According to the invention, the tool (1) has a shaft (2) with a lumen (6), on the distal end (1?) of which is situated a nozzle head (3) with at least two nozzles (4), wherein the nozzles (4) are spaced from each other at an angle of less than 180° and equally relative to a centre axis (M) of the shaft (2).

Abstract: The present invention refers to a set for the production of a ready-to-use chemo-therapeutic composition for intraperitoneal administration as an aerosol, wherein the set comprises an aqueous concentrate containing at least cisplatin in a first predetermined concentration and doxorubicin in a second predetermined concentration with a predetermined ratio of the first and the second concentration and having a pH value in the range from 3.0 to 7.0. The set further comprises a physiological aqueous carrier solution, which is for optional dilution of the concentrate depending on target concentrations of cisplatin and doxorubicin in the chemo-therapeutic composition to be applied. Further, the invention refers to a method for providing of a ready-for-use chemotherapeutic composition for intraperitoneal administration as an aerosol by using of a set, to a chemotherapeutic composition for intraperitoneal administration as an aerosol, and a use of the chemotherapeutic composition.

Abstract: A surgical instrument for electrotomy and a tool for the same are disclosed. In an embodiment a tool includes a tubular main body having at its distal end an opening in which an active electrode is arranged, wherein the active electrode has a J-shaped electrode body having a short, bent first portion protruding through the opening of the main body and an elongate, tubular second portion extending coaxially in the main body, and wherein the first portion and the second portion are integral.

Abstract: A surgical device and a method for using the surgical device are disclosed. In an embodiment the device for applying a substance (X) in a hollow space of a body cavity such as a hollow organ, in particular a therapeutic pneumoperitoneum, includes a trocar system with a trocar sleeve, the trocar system having a gas connection to which an insufflation gas-supply line can be connected and a nozzle system, which in its interior forms a lumen with a proximal end and a distal end, wherein the nozzle system has a needle nozzle fixed at the distal end of the lumen, and wherein the nozzle system is guided by the trocar sleeve.

Abstract: A device suitable for insertion into and for use within a tubular body cavity of a patient includes a first expandable fluid chamber for sealing a first section of the body cavity, an aerosol generating apparatus for generation of a therapeutic aerosol within a treatment section of the body cavity positioned adjacent to the first section, and an insufflation apparatus for insufflation of a gaseous medium into the treatment section of the body cavity.

Abstract: The invention relates to a device (1) for the directed application of a substance (X) in a hollow space (200), such as a hollow organ, of a body cavity, in particular a therapeutic pneumoperitoneum, comprising: a trocar system with a trocar sleeve (45), said trocar system (40) having a gas connection (43) to which an insufflation gas-supply line (81) can be connected, and a nozzle system (20), which in its interior forms a lumen (26), with a proximal end (21) and a distal end (22), wherein the nozzle system (20) has a needle nozzle (30) fixed at the distal end (22) with the lumen (26) and is guided by the trocar sleeve (45).