Patents by Inventor Alexander I. Agoulnik

Alexander I. Agoulnik has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Great gene and protein
    Publication number: 20030082650
    Abstract: The present invention is directed to a G protein-coupled receptor that is necessary for normal testicular descent during embryonic development. Mutations in this receptor lead to cryptorchidism. In addition to the receptor and genes encoding the receptor, the invention includes assays for mutations in the receptor gene, binding assays which utilize the receptor and transgenic animals which have been engineered to have non-functional receptor alleles. The animals may be used in assays designed to identify agents useful in treating cryptorchidism.
    Type: Application
    Filed: August 29, 2002
    Publication date: May 1, 2003
    Applicant: Baylor College of Medicine
    Inventor: Alexander I. Agoulnik
  • Can1 and its role in mammalian infertility
    Publication number: 20020119929
    Abstract: The present invention is directed to a Can1 mammalian sequence. Defects in this sequence result in aberrant migration and/or proliferation of primordial germ cells during embryonic development, leading to Sertoli Cell Only syndrome in males and Premature Ovarian Failure in females.
    Type: Application
    Filed: November 2, 2001
    Publication date: August 29, 2002
    Inventors: Colin E. Bishop, Alexander I. Agoulnik, Qichao Zhu
  • Male infertility Y-deletion detection battery
    Patent number: 5783390
    Abstract: The present disclosure describes a method for probing the integrity of a Y chromosome utilizing multiplex PCR reactions which amplify specific regions of the human Y chromosome which have been linked to normal fertility in human males. The method is capable of detecting deletion mutations within the Y chromosome which are predictive of human male infertility. A kit containing reagents needed to practice the method is also disclosed.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: July 21, 1998
    Assignee: Promega Corporation
    Inventors: Marijo Kent First, Alexander I. Agoulnik
  • Male infertility y-deletion detection battery
    Patent number: 5776682
    Abstract: The present disclosure describes a method for probing the integrity of a Y chromosome utilizing multiplex PCR reactions which amplify specific regions of the human Y chromosome which have been linked to normal fertility in human males. The method is capable of detecting deletion mutations within the Y chromosome which are predictive of human male infertility. A kit containing reagents needed to practice the method is also disclosed.
    Type: Grant
    Filed: September 18, 1995
    Date of Patent: July 7, 1998
    Assignee: Promega Corporation
    Inventors: Marijo Kent First, Alexander I. Agoulnik, Ariege Muallem