Patents by Inventor ALEXANDER KIRSCHENBAUM

ALEXANDER KIRSCHENBAUM has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bisphosphonate-Prostatic Acid Phosphatase Inhibitor Conjugates To Treat Prostate Cancer Bone Metastasis
    Publication number: 20140045797
    Abstract: The present invention concerns conjugate compounds comprising a bisphosphonate covalently bonded to a prostatic acid phosphatase inhibitor and compositions comprising such conjugates. Methods for treating and inhibiting prostate cancer bone metastases, and determining whether a conjugate is useful for such treatment are also provided. In some instances, the bisphosphonate is alendronate, and it is covalently bonded to either tartaric acid or glyceric acid.
    Type: Application
    Filed: October 16, 2013
    Publication date: February 13, 2014
    Applicants: LEHIGH UNIVERSITY, MOUNT SINAI SCHOOL OF MEDICINE
    Inventors: ALEXANDER KIRSCHENBAUM, ALICE C. LEVINE, STEVEN L. REGEN, VACLAV JANOUT
  • BISPHOSPHONATE-PROSTATIC ACID PHOSPHATASE INHIBITOR CONJUGATES TO TREAT PROSTATE CANCER BONE METASTASIS
    Publication number: 20110065672
    Abstract: The present invention concerns conjugate compounds comprising a bisphosphonate covalently bonded to a prostatic acid phosphatase inhibitor and compositions comprising such conjugates. Methods for treating and inhibiting prostate cancer bone metastases, and determining whether a conjugate is useful for such treatment are also provided. In some instances, the bisphosphonate is alendronate, and it is covalently bonded to either tartaric acid or glyceric acid.
    Type: Application
    Filed: September 16, 2010
    Publication date: March 17, 2011
    Applicants: MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY, LEHIGH UNIVERSITY
    Inventors: ALEXANDER KIRSCHENBAUM, ALICE C. LEVINE, STEVEN L. REGEN, VACLAV JANOUT