Patents by Inventor Alexander Levitzki

Alexander Levitzki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Certain indole compounds which inhibit EGF receptor tyrosine kinase
    Patent number: 5196446
    Abstract: Heteroarylethenediyl compounds wherein the heteroaryl group can be mono- or icyclic heteroaryl and the aryl group can be or mono- or bicyclic carbocyclic, said compound optionally substituted or polysubstituted, with the proviso that the heteroaryl group is not furyl or thienyl when the ethenediyl group has geminal cyano substituents, and pharmaceutical compositions comprising said compounds, and the use thereof for inhibiting a protein tyrosine kinase portion of a receptor selected from epidermal growth factor and platelet derived growth factor in a patient suffering from such disorder.
    Type: Grant
    Filed: April 16, 1991
    Date of Patent: March 23, 1993
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Alexander Levitzki, Chaim Gilon, Aviv Gazit