Abstract: Systems and methods for generating a preview stream for a user of a video conferencing service. In some aspects, the systems and methods provide for receiving a video stream of at least a portion of a display screen of a user device and determining whether the user device has been designated as a receiving device for receiving a version of the video stream. In response to determining that the user device has not been designated as a receiving device for receiving a version of the video stream, a request is generated to designate the user device as a receiving device in addition to being a presenting device. Based on images of the video stream, a preview stream (e.g., of at least a portion of the display screen) is generated and transmitted for display at the user device.

Abstract: A method for operating an air guiding device of a motor vehicle includes adjusting an air guiding element of the air guiding device from a starting position into an active position which influences aerodynamics of the motor vehicle. The method further includes exerting feedback pertaining to the adjusting of the air guiding element on a motor vehicle occupant in a form of a relative movement acting on the motor vehicle occupant, where the relative movement is generated by an adjustment of a chassis and/or a seat system of the motor vehicle from a first position to a second position.

Abstract: The present disclosure relates to recombinant binding proteins comprising a designed ankyrin repeat domain with binding specificity for 4-1 BB (CD 137). In addition, the disclosure relates to nucleic acids encoding such binding proteins, pharmaceutical compositions comprising such binding proteins or nucleic acids, and the use of such binding proteins, nucleic acids or pharmaceutical compositions in methods for activating 4-1 BB in cells expressing 4-1 BB, e.g., tumor-localized T-lymphocytes, and for treating or diagnosing diseases, such as cancer, in a mammal, including a human.

Abstract: This disclosure relates to multispecific recombinant proteins useful for the treatment of cancer.

Abstract: A simple, rapid, inexpensive, and promising commercial biomarker assay method for multiple diseases is described herein. The present invention detects miRNA-based biomarkers in human stool specimens. The method of the present invention amplifies miRNA directly from stool specimens without any prior miRNA extraction. Differential expression of specific microRNAs in stool of colorectal cancer CRC and adenoma patients suggest fecal microRNAs as a novel potential biomarker for colorectal neoplasia detection. The method of the present invention has diagnostic, prognostic, and therapeutic relevance for gastroenterological cancers/colorectal cancer and as well as further acquired or hereditary GI diseases.

Abstract: A simple, rapid, inexpensive, and promising commercial biomarker assay method for multiple diseases is described herein. The present invention detects miRNA-based biomarkers in human stool specimens. The method of the present invention amplifies miRNA directly from stool specimens without any prior miRNA extraction. Differential expression of specific microRNAs in stool of colorectal cancer CRC and adenoma patients suggest fecal microRNAs as a novel potential biomarker for colorectal neoplasia detection. The method of the present invention has diagnostic, prognostic, and therapeutic relevance for gastroenterological cancers/colorectal cancer and as well as further acquired or hereditary GI diseases.