Abstract: A biocompatible electrical connection includes a substrate; a ferrule having a concentric flange at a first end of the ferrule; a first adhesive; and a second adhesive. The first adhesive adheres a first surface of the concentric flange of the ferrule to a surface of the substrate. The second adhesive fills an annular space between a hole in the substrate and the ferrule. The first adhesive or the second adhesive forms a conductive path on the surface of the substrate between the ferrule and a circuit pattern on the substrate.

Abstract: A biocompatible electrical connection includes a substrate; a ferrule having a concentric flange at a first end of the ferrule; a first adhesive; and a second adhesive. The first adhesive adheres a first surface of the concentric flange of the ferrule to a surface of the substrate. The second adhesive fills an annular space between a hole in the substrate and the ferrule. The first adhesive or the second adhesive forms a conductive path on the surface of the substrate between the ferrule and a circuit pattern on the substrate.

Abstract: A biocompatible electrical connection includes: a substrate; a ferrule having a concentric flange at a first end of the ferrule; a first adhesive; and a second adhesive. The substrate includes a hole having a diameter that is a specified amount larger than an outside diameter of the ferrule forming an annular space between the hole and the ferrule, the first adhesive adheres a first surface of the concentric flange of the ferrule to a first surface of the substrate, and the second adhesive fills the annular space between the hole and the ferrule.

Abstract: The present disclosure relates to implantable neuromodulation devices and methods of fabrication, and in particular to a separable high density connectors for implantable neuromodulation devices. Particularly, aspects of the present disclosure are directed to a medical device comprising an electronics module and a header for connecting the electronics module to a lead assembly. The header includes: a housing that includes (i) a cavity having a central axis or plane and an internal surface, and (ii) an opening aligned with the central axis or plane of the cavity, an array of retractable contacts extending from the internal surface towards the central axis or plane of the cavity, and an array of connection terminals on the housing, where each connection terminal of the array of connection terminals is: (i) electrically connected to the electronics module, and (ii) electrically connectable to a retractable contact of the array of retractable contacts.

Abstract: An implantable medical device is described. The implantable medical device includes an enclosure for receiving and hermitically sealing active components. A header is connected to the enclosure and encloses other components of the device. A communications antenna is encapsulated in a bio-compatible material and connected to an exterior surface of the enclosure. The communications antenna is electrically connected to the active components via an access window of the header. The access window is backfilled after the connections are made.

Abstract: In one embodiment, a method is provided comprising analyte testing on one or more types of samples.

Abstract: Devices, systems and methods including a sonicator for sample preparation are provided. A sonicator may be used to mix, resuspend, aerosolize, disperse, disintegrate, or de-gas a solution. A sonicator may be used to disrupt a cell, such as a pathogen cell in a sample. Sample preparation may include exposing pathogen-identifying material by sonication to detect, identify, or measure pathogens. A sonicator may transfer ultrasonic energy to the sample solution by contacting its tip to an exterior wall of a vessel containing the sample. Multipurpose devices including a sonicator also include further components for additional actions and assays. Devices, and systems comprising such devices, may communicate with a laboratory or other devices in a system for sample assay and analysis. Methods utilizing such devices and systems are provided. The improved sample preparation devices, systems and methods are useful for analyzing samples, e.g. for diagnosing patients suffering from infection by pathogens.

Abstract: An implantable pulse generator is provided that includes a power source, a wireless communication component configured to facilitate wireless communication with a non-implanted device and pulse-generating circuitry connected to the power source. The pulse-generating circuitry can be configured to identify, based on wireless communication with the non-implanted device, temporal and amplitude characteristics for electrical pulse stimuli and to trigger electrical output stimuli having the temporal and amplitude characteristics. The implantable pulse generation can further include one or more lead connections—each being shaped to engage a lead and electrically connected to the pulse-generating circuitry to enable the lead to deliver at least part of the electrical output stimuli triggered by the pulse-generating circuitry. The implantable pulse generator can further include one or more suture-engagement components, each including one or more holes each having a diameter that is at least 0.1 mm and less than 5 mm.

Abstract: Embodiment includes of a method and a system of network based operation of an unmanned aerial vehicle is disclosed. One system includes a drone user machine, a drone control machine, and a drone control console. The drone control machine is interfaced with the drone user machine through a network, and the drone control machine is interfaced with a drone through the drone control console. The drone control machine operates to receive user commands from the drone user machine through the network, generate drone control commands which are provided to the drone control console for controlling the drone, wherein the drone control commands are generated based on the user commands, receive video from the drone control console that was generated by a camera located on the drone, and communicate the video to the drone user machine over the network, wherein the video is displayed on a display associated with the drone user machine.

Abstract: Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample.

Abstract: Devices, systems and methods including a sonicator for sample preparation are provided. A sonicator may be used to mix, resuspend, aerosolize, disperse, disintegrate, or de-gas a solution. A sonicator may be used to disrupt a cell, such as a pathogen cell in a sample. Sample preparation may include exposing pathogen-identifying material by sonication to detect, identify, or measure pathogens. A sonicator may transfer ultrasonic energy to the sample solution by contacting its tip to an exterior wall of a vessel containing the sample. Multipurpose devices including a sonicator also include further components for additional actions and assays. Devices, and systems comprising such devices, may communicate with a laboratory or other devices in a system for sample assay and analysis. Methods utilizing such devices and systems are provided. The improved sample preparation devices, systems and methods are useful for analyzing samples, e.g. for diagnosing patients suffering from infection by pathogens.

Abstract: Embodiment includes of a method and a system of network based operation of an unmanned aerial vehicle is disclosed. One system includes a drone user machine, a drone control machine, and a drone control console. The drone control machine is interfaced with the drone user machine through a network, and the drone control machine is interfaced with a drone through the drone control console. The drone control machine operates to receive user commands from the drone user machine through the network, generate drone control commands which are provided to the drone control console for controlling the drone, wherein the drone control commands are generated based on the user commands, receive video from the drone control console that was generated by a camera located on the drone, and communicate the video to the drone user machine over the network, wherein the video is displayed on a display associated with the drone user machine.

Abstract: A biocompatible electrical connection includes: a substrate; a ferrule having a concentric flange at a first end of the ferrule; a first adhesive; and a second adhesive. The substrate includes a hole having a diameter that is a specified amount larger than an outside diameter of the ferrule forming an annular space between the hole and the ferrule, the first adhesive adheres a first surface of the concentric flange of the ferrule to a first surface of the substrate, and the second adhesive fills the annular space between the hole and the ferrule.

Abstract: Embodiment includes of a method and a system of network based operation of an unmanned aerial vehicle is disclosed. One system includes a drone user machine, a drone control machine, and a drone control console. The drone control machine is interfaced with the drone user machine through a network, and the drone control machine is interfaced with a drone through the drone control console. The drone control machine operates to receive user commands from the drone user machine through the network, generate drone control commands which are provided to the drone control console for controlling the drone, wherein the drone control commands are generated based on the user commands, receive video from the drone control console that was generated by a camera located on the drone, and communicate the video to the drone user machine over the network, wherein the video is displayed on a display associated with the drone user machine.

Abstract: The invention relates to a thermodynamic energy converter (1) with at least one first and one second volume element (10a, 10b) for enclosing a working medium (102) inside a variable inner volume, including a wall that divides the inner volume into heat exchanger compartments (110, 120) and a working compartment (200), wherein a partition (230) is formed inside the working compartment (200) which divides the working compartment (200) into a working chamber (210) supplied with the working medium (201) and a force transmission chamber (212) supplied with a displacement fluid (202), the heat exchanger compartments (110, 120) and the working chamber (210) are interconnected such that the working medium (102) inside the volume element (10a, 10b) has the same pressure, and each heat exchanger compartment (110, 120) is connected to the working chamber (210) via an inlet and an outlet that is formed separately from the inlet.

Abstract: In one embodiment, a method is provided comprising analyte testing on one or more types of samples.

Abstract: Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample.

Abstract: In one embodiment, a method is provided comprising analyte testing on one or more types of samples.

Abstract: A system has a drone session server to collect drone session information. A drone user machine is in a client relationship with the drone session server. A drone control machine is in a client relationship with the drone session server and a peer-to-peer relationship with the drone user machine. The drone control machine is configured to relay video data from a drone to the drone user machine via a peer-to-peer connection. The drone control machine evaluates user commands collected by the drone user machine that are relayed to the drone control machine via the peer-to-peer connection to produce enforced limits commands to maintain the drone within a three-dimensional geographical fence. The drone control machine sends autopilot commands to the drone to transport the drone from the three-dimensional geographical fence to a land site to complete a drone session.

Abstract: Devices, systems and methods including a sonicator for sample preparation are provided. A sonicator may be used to mix, resuspend, aerosolize, disperse, disintegrate, or de-gas a solution. A sonicator may be used to disrupt a cell, such as a pathogen cell in a sample. Sample preparation may include exposing pathogen-identifying material by sonication to detect, identify, or measure pathogens. A sonicator may transfer ultrasonic energy to the sample solution by contacting its tip to an exterior wall of a vessel containing the sample. Multipurpose devices including a sonicator also include further components for additional actions and assays. Devices, and systems comprising such devices, may communicate with a laboratory or other devices in a system for sample assay and analysis. Methods utilizing such devices and systems are provided. The improved sample preparation devices, systems and methods are useful for analyzing samples, e.g. for diagnosing patients suffering from infection by pathogens.