Abstract: Display of cross-sell advertisements to a user, including, but not limited to, in a social genetics network includes: associating genetic data with product and service categories; accessing specific genetic data of a user to obtain a set of product and service categories associated with the genetic data of the user; analyzing non-genetic data of the user, including past purchase history, and analyzing the genetic data of the user to discover correlations in preferences of the user; selecting one or more desired product and service categories from the set of the product and service categories that match the correlations in the preferences of the user; sending a product or service request to at least one advertiser for a cross-sell advertisement relating to the desired product and service categories; and responsive to receiving the cross-sell advertisement from the advertiser, displaying the cross-sell advertisement on an electronic device of the user.

Abstract: Creation of a social genetics network that provides personal and business services includes: receiving non-genetic data and genetic data about a user and storing the non-genetic data and genetic data in a database; analyzing the genetic data and the non-genetic data to i) assign traits to the user based at least in part on phenotypic and/or genotypic relationships found in the genetic data and the non-genetic data, and ii) determine trait connections between the user and other users in the network based on a similarity of the traits that are common to the user and the other users; and generating and displaying on an electronic device a social genetics profile that includes at least a portion of the non-genetic data, at least a portion of the traits assigned to the user, and at least a portion of the trait connections of the user to the other users.

Abstract: One aspect of the invention provides a patient tissue state monitoring system with a light source; a light detector; a probe adapted to be inserted into a patient to transmit light from the light source to an organ tissue site and to direct light from the organ tissue site to the detector; and a processor programmed to determine tissue state with respect to a tissue site pre-dysoxia point from a fluorescence emission detected by the detector (such as by determining tissue NADH concentration) and to provide an indication of tissue state through an output device (such as by displaying a numerical value corresponding to the fluorescence emission).

Abstract: A method and device for assaying sperm motility in a forward direction and density of active sperm in a semen sample are disclosed. The device includes a microfluidics structure having a sample reservoir, a downstream collection region and a microchannel extending therebetween. The microchannel is dimensioned to confine sample sperm to single-direction movement within the channel, such that sperm in a semen sample placed in the sample reservoir enter and migrate along the microchannel toward and into the collection region. Also included is a detector for detecting the presence of labeled sperm in the microchannel or collection region, and an electronics unit operatively connected to the detector for (i) receiving detector signals, (ii) based on the detector signals received, determining sperm motility and density in the sperm sample, and (iii) displaying information related to sperm motility and density.

Abstract: A diagnostics apparatus for detecting fluorescence events related to the presence of an analyte in a sample is disclosed. The apparatus includes a housing, a source of excitation light and a photodetector, and a unitary multi-surface optical module. The optical module is integrally formed and composed of an upstream portion having a focusing optical surface for directing excitation light from the light source to a focal region within an analyte-detection zone in the apparatus, and a downstream portion having a second focusing powered optical surface and at least one reflecting surface for directing fluorescence-emission light produced by fluorescence events within the detection zone, in a direction substantially normal to the path of the excitation light onto the photodetector. The optical module is adaptable to a variety of assay formats, including multiple-sample, sample-array, and disposable-cartridge formats.

Abstract: A method and device for assaying sperm motility in a forward direction and density of active sperm in a semen sample are disclosed. The device includes a microfluidics structure having a sample reservoir, a downstream collection region and a microchannel extending therebetween. The microchannel is dimensioned to confine sample sperm to single-direction movement within the channel, such that sperm in a semen sample placed in the sample reservoir enter and migrate along the microchannel toward and into the collection region. Also included is a detector for detecting the presence of labeled sperm in the microchannel or collection region, and an electronics unit operatively connected to the detector for (i) receiving detector signals, (ii) based on the detector signals received, determining sperm motility and density in the sperm sample, and (iii) displaying information related to sperm motility and density.

Abstract: A method and device for assaying sperm motility in a forward direction and density of active sperm in a semen sample are disclosed. The device includes a microfluidics structure having a sample reservoir, a downstream collection region and a microchannel extending therebetween. The microchannel is dimensioned to confine sample sperm to single-direction movement within the channel, such that sperm in a semen sample placed in the sample reservoir enter and migrate along the microchannel toward and into the collection region. Also included is a detector for detecting the presence of labeled sperm in the microchannel or collection region, and an electronics unit operatively connected to the detector for (i) receiving detector signals, (ii) based on the detector signals received, determining sperm motility and density in the sperm sample, and (iii) displaying information related to sperm motility and density.