Patents by Inventor Alexander M. Harmon

Alexander M. Harmon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cartilage and bone repair and regeneration using postpartum-derived cells
    Patent number: 11191789
    Abstract: Cells derived from postpartum tissue and methods for their isolation and induction to differentiate to cells of a chondrogenic or osteogenic phenotype are provided by the invention. The invention further provides cultures and compositions of the postpartum-derived cells and products related thereto. The postpartum-derived cells of the invention and products related thereto have a plethora of uses, including but not limited to research, diagnostic, and therapeutic applications, for example, in the treatment of bone and cartilage conditions.
    Type: Grant
    Filed: June 25, 2004
    Date of Patent: December 7, 2021
    Assignee: Depuy Synthes Products, Inc.
    Inventors: Anthony J. Kihm, Agnieszka Seyda, Sridevi Dhanaraj, Ziwei Wang, Alexander M. Harmon, Ian Ross Harris, Darin J. Messina, Sanjay Mistry, Anna Gosiewska, Chin-Feng Yi
  • Postpartum cells derived from placental tissue, and methods of making and using the same
    Patent number: 11000554
    Abstract: Cells derived from postpartum placenta and methods for their isolation are provided by the invention. The invention further provides cultures and compositions of the placenta-derived cells. The placenta-derived cells of the invention have a plethora of uses, including but not limited to research, diagnostic, and therapeutic applications.
    Type: Grant
    Filed: March 4, 2019
    Date of Patent: May 11, 2021
    Assignee: DePuy Synthes Products, Inc.
    Inventors: Anthony J. Kihm, Ian R. Harris, Sanjay Mistry, Alexander M. Harmon, Darin J. Messina, Agnieszka Seyda, Chin-Feng Yi, Anna Gosiewska
  • Soft tissue repair and regeneration using postpartum-derived cells and cell products
    Patent number: 10758576
    Abstract: Cells derived from postpartum tissue and products thereof having the potential to support cells of and/or differentiate to cells of a soft tissue lineage, and methods of preparation and use of those postpartum tissue-derived cells, are provided by the invention. The invention also provides methods for the use of such postpartum-derived cells and products related thereto in therapies for conditions of soft tissue.
    Type: Grant
    Filed: August 6, 2018
    Date of Patent: September 1, 2020
    Assignee: DePuy Synthes Products, Inc.
    Inventors: Laura J. Brown, Alexander M. Harmon, Anna Gosiewska
  • Postpartum cells derived from umbilical cord tissue, and methods of making and using the same
    Patent number: 10500234
    Abstract: Cells derived from human umbilical cords are disclosed along with methods for their therapeutic use. Isolation techniques, culture methods and detailed characterization of the cells with respect to their cell surface markers, gene expression, and their secretion of trophic factors are described.
    Type: Grant
    Filed: July 27, 2017
    Date of Patent: December 10, 2019
    Assignee: DePuy Synthes Products, Inc.
    Inventors: Sanjay Mistry, Anthony J. Kihm, Ian R. Harris, Alexander M. Harmon, Darin J. Messina, Agnieszka Seyda, Chin-Feng Yi, Anna Gosiewska
  • Postpartum cells derived from placental tissue, and methods of making and using the same
    Patent number: 10383898
    Abstract: Cells derived from postpartum placenta and methods for their isolation are provided by the invention. The invention further provides cultures and compositions of the placenta-derived cells. The placenta-derived cells of the invention have a plethora of uses, including but not limited to research, diagnostic, and therapeutic applications.
    Type: Grant
    Filed: February 27, 2017
    Date of Patent: August 20, 2019
    Assignee: Depuy Synthes Products, Inc.
    Inventors: Anthony J. Kihm, Ian Ross Harris, Sanjay Mistry, Alexander M. Harmon, Darin J. Messina, Agnieszka Seyda, Chin-Feng Yi, Anna Gosiewska
  • POSTPARTUM CELLS DERIVED FROM PLACENTAL TISSUE, AND METHODS OF MAKING AND USING THE SAME
    Publication number: 20190192577
    Abstract: Cells derived from postpartum placenta and methods for their isolation are provided by the invention. The invention further provides cultures and compositions of the placenta-derived cells. The placenta-derived cells of the invention have a plethora of uses, including but not limited to research, diagnostic, and therapeutic applications.
    Type: Application
    Filed: March 4, 2019
    Publication date: June 27, 2019
    Applicant: DePuy Synthes Products, Inc.
    Inventors: Anthony J. Kihm, Ian R. Harris, Sanjay Mistry, Alexander M. Harmon, Darin J. Messina, Agnieszka Seyda, Chin-Feng Yi, Anna Gosiewska
  • Postpartum cells derived from placental tissue, and methods of making and using the same
    Patent number: 10220059
    Abstract: Cells derived from postpartum placenta and methods for their isolation are provided by the invention. The invention further provides cultures and compositions of the placenta-derived cells. The placenta-derived cells of the invention have a plethora of uses, including but not limited to research, diagnostic, and therapeutic applications.
    Type: Grant
    Filed: February 27, 2017
    Date of Patent: March 5, 2019
    Assignee: DEPUY SYNTHES PRODUCTS, INC.
    Inventors: Anthony J. Kihm, Ian Ross Harris, Sanjay Mistry, Alexander M. Harmon, Darin J. Messina, Agnieszka Seyda, Chin-Feng Yi, Anna Gosiewska
  • Postpartum cells derived from placental tissue, and methods of making and using the same
    Patent number: 10195233
    Abstract: Cells derived from postpartum placenta and methods for their isolation are provided by the invention. The invention further provides cultures and compositions of the placenta-derived cells. The placenta-derived cells of the invention have a plethora of uses, including but not limited to research, diagnostic, and therapeutic applications.
    Type: Grant
    Filed: February 27, 2017
    Date of Patent: February 5, 2019
    Assignee: DePuy Synthes Products, Inc.
    Inventors: Anthony J. Kihm, Ian Ross Harris, Sanjay Mistry, Alexander M. Harmon, Darin J. Messina, Agnieszka Seyda, Chin-Feng Yi, Anna Gosiewska
  • Conditioned media and methods of making a conditioned media
    Patent number: 10179900
    Abstract: A stable and scalable process is provided to manufacture reduced serum umbilical cord tissue-derived (UTC)-conditioned media. The method includes the culture of a UTC under reduced serum conditions. Subsequently, the UTC is washed and grown in serum-free basal media. After approximately 24 hours, the conditioned media is collected, filtered and concentrated by use of an approximately 5 kDa or similar cut-off membrane.
    Type: Grant
    Filed: December 19, 2008
    Date of Patent: January 15, 2019
    Assignee: DEPUY SYNTHES PRODUCTS, INC.
    Inventors: Alexander M. Harmon, Abel Ang
  • SOFT TISSUE REPAIR AND REGENERATION USING POSTPARTUM-DERIVED CELLS AND CELL PRODUCTS
    Publication number: 20180338999
    Abstract: Cells derived from postpartum tissue and products thereof having the potential to support cells of and/or differentiate to cells of a soft tissue lineage, and methods of preparation and use of those postpartum tissue-derived cells, are provided by the invention. The invention also provides methods for the use of such postpartum-derived cells and products related thereto in therapies for conditions of soft tissue.
    Type: Application
    Filed: August 6, 2018
    Publication date: November 29, 2018
    Applicant: DePuy Synthes Products, Inc.
    Inventors: Laura J. Brown, Alexander M. Harmon, Anna Gosiewska
  • Soft tissue repair and regeneration using postpartum-derived cells and cell products
    Patent number: 10039793
    Abstract: Cells derived from postpartum tissue and products thereof having the potential to support cells of and/or differentiate to cells of a soft tissue lineage, and methods of preparation and use of those postpartum tissue-derived cells, are provided by the invention. The invention also provides methods for the use of such postpartum-derived cells and products related thereto in therapies for conditions of soft tissue.
    Type: Grant
    Filed: November 28, 2016
    Date of Patent: August 7, 2018
    Assignee: DEPUY SYNTHES PRODUCTS, INC.
    Inventors: Laura J. Brown, Alexander M. Harmon, Anna Gosiewska
  • POSTPARTUM CELLS DERIVED FROM UMBILICAL CORD TISSUE, AND METHODS OF MAKING AND USING THE SAME
    Publication number: 20170326183
    Abstract: Cells derived from human umbilical cords are disclosed along with methods for their therapeutic use. Isolation techniques, culture methods and detailed characterization of the cells with respect to their cell surface markers, gene expression, and their secretion of trophic factors are described.
    Type: Application
    Filed: July 27, 2017
    Publication date: November 16, 2017
    Applicant: DePuy Synthes Products, Inc.
    Inventors: Sanjay Mistry, Anthony J. Kihm, Ian R. Harris, Alexander M. Harmon, Darin J. Messina, Agnieszka Seyda, Chin-Feng Yi, Anna Gosiewska
  • POSTPARTUM CELLS DERIVED FROM PLACENTAL TISSUE, AND METHODS OF MAKING AND USING THE SAME
    Publication number: 20170239299
    Abstract: Cells derived from postpartum placenta and methods for their isolation are provided by the invention. The invention further provides cultures and compositions of the placenta-derived cells. The placenta-derived cells of the invention have a plethora of uses, including but not limited to research, diagnostic, and therapeutic applications.
    Type: Application
    Filed: February 27, 2017
    Publication date: August 24, 2017
    Applicant: DePuy Synthes Products, Inc.
    Inventors: Anthony J. Kihm, Ian Ross Harris, Sanjay Mistry, Alexander M. Harmon, Darin J. Messina, Agnieszka Seyda, Chin-Feng Yi, Anna Gosiewska
  • Postpartum cells derived from umbilical cord tissue, and methods of making and using the same
    Patent number: 9717763
    Abstract: Cells derived from human umbilical cords are disclosed along with methods for their therapeutic use. Isolation techniques, culture methods and detailed characterization of the cells with respect to their cell surface markers, gene expression, and their secretion of trophic factors are described.
    Type: Grant
    Filed: September 5, 2013
    Date of Patent: August 1, 2017
    Assignee: DEPUY SYNTHES PRODUCTS, INC.
    Inventors: Sanjay Mistry, Anthony J. Kihm, Ian R. Harris, Alexander M. Harmon, Darin J. Messina, Agnieszka Seyda, Chin-Feng Yi, Anna Gosiewska
  • POSTPARTUM CELLS DERIVED FROM PLACENTAL TISSUE, AND METHODS OF MAKING AND USING THE SAME
    Publication number: 20170166864
    Abstract: Cells derived from postpartum placenta and methods for their isolation are provided by the invention. The invention further provides cultures and compositions of the placenta-derived cells. The placenta-derived cells of the invention have a plethora of uses, including but not limited to research, diagnostic, and therapeutic applications.
    Type: Application
    Filed: February 27, 2017
    Publication date: June 15, 2017
    Applicant: DePuy Synthes Products, Inc.
    Inventors: Anthony J. Kihm, Ian Ross Harris, Sanjay Mistry, Alexander M. Harmon, Darin J. Messina, Agnieszka Seyda, Chin-Feng Yi, Anna Gosiewska
  • POSTPARTUM CELLS DERIVED FROM PLACENTAL TISSUE, AND METHODS OF MAKING AND USING THE SAME
    Publication number: 20170166863
    Abstract: Cells derived from postpartum placenta and methods for their isolation are provided by the invention. The invention further provides cultures and compositions of the placenta-derived cells. The placenta-derived cells of the invention have a plethora of uses, including but not limited to research, diagnostic, and therapeutic applications.
    Type: Application
    Filed: February 27, 2017
    Publication date: June 15, 2017
    Applicant: DePuy Synthes Products, Inc.
    Inventors: Anthony J. Kihm, Ian Ross Harris, Sanjay Mistry, Alexander M. Harmon, Darin J. Messina, Agnieszka Seyda, Chin-Feng Yi, Anna Gosiewska
  • SOFT TISSUE REPAIR AND REGENERATION USING POSTPARTUM-DERIVED CELLS AND CELL PRODUCTS
    Publication number: 20170143770
    Abstract: Cells derived from postpartum tissue and products thereof having the potential to support cells of and/or differentiate to cells of a soft tissue lineage, and methods of preparation and use of those postpartum tissue-derived cells, are provided by the invention. The invention also provides methods for the use of such postpartum-derived cells and products related thereto in therapies for conditions of soft tissue.
    Type: Application
    Filed: November 28, 2016
    Publication date: May 25, 2017
    Applicant: DePuy Synthes Products, Inc.
    Inventors: Laura J. Brown, Alexander M. Harmon, Anna Gosiewska
  • Postpartum cells derived from placental tissue, and methods of making and using the same
    Patent number: 9579351
    Abstract: Cells derived from postpartum placenta and methods for their isolation are provided by the invention. The invention further provides cultures and compositions of the placenta-derived cells. The placenta-derived cells of the invention have a plethora of uses, including but not limited to research, diagnostic, and therapeutic applications.
    Type: Grant
    Filed: June 25, 2004
    Date of Patent: February 28, 2017
    Assignee: DePuy Synthes Products, Inc.
    Inventors: Anthony J. Kihm, Ian Ross Harris, Sanjay Mistry, Alexander M. Harmon, Darin J. Messina, Agnieszka Seyda, Chin-Feng Yi, Anna Gosiewska
  • Regeneration and repair of neural tissue using postpartum-derived cells
    Patent number: 9572840
    Abstract: Cells derived from postpartum umbilicus and placenta are disclosed. Pharmaceutical compositions, devices and methods for the regeneration or repair of neural tissue using the postpartum-derived cells are also disclosed.
    Type: Grant
    Filed: January 10, 2014
    Date of Patent: February 21, 2017
    Assignee: DePuy Synthes Products, Inc.
    Inventors: Darin J. Messina, Alexander M. Harmon, Ian R. Harris, Anthony J. Kihm, Sanjay Mistry, Agnieszka Seyda, Chin-Feng Yi, Anna Gosiewska
  • Soft tissue repair and regeneration using postpartum-derived cells and cell products
    Patent number: 9504719
    Abstract: Cells derived from postpartum tissue and products thereof having the potential to support cells of and/or differentiate to cells of a soft tissue lineage, and methods of preparation and use of those postpartum tissue-derived cells, are provided by the invention. The invention also provides methods for the use of such postpartum-derived cells and products related thereto in therapies for conditions of soft tissue.
    Type: Grant
    Filed: December 22, 2005
    Date of Patent: November 29, 2016
    Assignee: DePuy Synthes Products, Inc.
    Inventors: Laura Brown, Alexander M. Harmon, Anna Gosiewska