Patents by Inventor Alexander MAZO

Alexander MAZO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DRUG-INDUCED EPIGENETIC REMODELING TO PREVENT FIBROSIS
    Publication number: 20220401454
    Abstract: A therapeutic treatment for preventing or reducing the formation of fibrosis comprising administering to a patient a UTX or JMJD3 inhibitor that are effective in preventing or reducing fibrosis in situations wherein access to an injury or dysmorphogenetic tissues before the fibrotic process becomes established in the tissues.
    Type: Application
    Filed: July 7, 2022
    Publication date: December 22, 2022
    Applicant: Thomas Jefferson University
    Inventors: Janice L. Walker, Alexander Mazo, Svetlana Petruk, A. Sue Menko
  • METHODS FOR REPROGRAMMING CANCER CELLS
    Publication number: 20220362254
    Abstract: The present invention relates to methods and compositions for the treatment of cancer in a subject in need thereof by treatments that reprogram the cancer cells.
    Type: Application
    Filed: August 21, 2020
    Publication date: November 17, 2022
    Inventors: Alexander Mazo, Bruno Calabretta, Svetlana Petruk, Patrizia Porazzi, David Deming
  • METHODS FOR ENHANCING DNA DAMAGE AND APOPTOSIS OF LEUKEMIC CELLS
    Publication number: 20220354845
    Abstract: The present invention relates to methods of treating cancer in a subject in need thereof by treatments which enhance DNA damage and apoptosis of leukemic cells.
    Type: Application
    Filed: August 21, 2020
    Publication date: November 10, 2022
    Inventors: Bruno Calabretta, Alexander Mazo, Svetlana Petruk, Patrizia Porazzi
  • Drug-induced epigenetic remodeling to prevent fibrosis
    Patent number: 11400099
    Abstract: A therapeutic treatment for preventing or reducing the formation of fibrosis comprising administering to a patient a UTX or JMJD3 inhibitor that are effective in preventing or reducing fibrosis in situations wherein access to an injury or dysmorphogenetic tissues before the fibrotic process becomes established in the tissues.
    Type: Grant
    Filed: September 25, 2017
    Date of Patent: August 2, 2022
    Assignee: THOMAS JEFFERSON UNIVERSITY
    Inventors: Janice L. Walker, Alexander Mazo, Svetlana Petruk, A. Sue Menko
  • DRUG-INDUCED EPIGENETIC REMODELING TO PREVENT FIBROSIS
    Publication number: 20200016166
    Abstract: A therapeutic treatment for preventing or reducing the formation of fibrosis comprising administering to a patient a UTX or JMJD3 inhibitor that are effective in preventing or reducing fibrosis in situations wherein access to an injury or dysmorphogenetic tissues before the fibrotic process becomes established in the tissues.
    Type: Application
    Filed: September 25, 2017
    Publication date: January 16, 2020
    Applicant: Thomas Jefferson University
    Inventors: Janice L. WALKER, Alexander MAZO, Svetlana PETRUK, Sue A. MENKO