Patents by Inventor Alexander Munishkin

Alexander Munishkin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7556919
    Abstract: Long oligonucleotide arrays, as well as methods for their preparation and use in hybridization assays, are provided. The subject arrays are characterized in that at least a portion of the probes of the array, and usually all of the probes of the array, are long oligonucleotides, e.g. oligonucleotides having a length of from about 50 to 120 nt. Each long oligonucleotide probe on the array is preferably chosen to exhibit substantially the same high target binding efficiency and substantially the same low non-specific binding under conditions in which the array is employed. The subject arrays find use in a number of different applications, e.g. differential gene expression analysis.
    Type: Grant
    Filed: November 9, 2004
    Date of Patent: July 7, 2009
    Assignee: Clontech Laboratories, Inc.
    Inventors: Alex Chenchik, Alexander Munishkin, Peter Simonenko
  • Patent number: 7041445
    Abstract: Long oligonucleotide arrays, as well as methods for their preparation and use in hybridization assays, are provided. The subject arrays are characterized in that at least a portion of the probes of the array, and usually all of the probes of the array, are long oligonucleotides, e.g. oligonucleotides having a length of from about 50 to 120 nt. Each long oligonucleotide probe on the array is preferably chosen to exhibit substantially the same high target binding efficiency and substantially the same low non-specific binding under conditions in which the array is employed. The subject arrays find use in a number of different applications, e.g. differential gene expression analysis.
    Type: Grant
    Filed: November 15, 1999
    Date of Patent: May 9, 2006
    Assignee: Clontech Laboratories, Inc.
    Inventors: Alex Chenchik, Alexander Munishkin, Peter Simonenko
  • Publication number: 20060068403
    Abstract: Long oligonucleotide arrays, as well as methods for their preparation and use in hybridization assays, are provided. The subject arrays are characterized in that at least a portion of the probes of the array, and usually all of the probes of the array, are long oligonucleotides, e.g. oligonucleotides having a length of from about 50 to 120 nt. Each long oligonucleotide probe on the array is preferably chosen to exhibit substantially the same high target binding efficiency and substantially the same low non-specific binding under conditions in which the array is employed. The subject arrays find use in a number of different applications, e.g. differential gene expression analysis.
    Type: Application
    Filed: November 9, 2004
    Publication date: March 30, 2006
    Inventors: Alex Chenchik, Alexander Munishkin, Peter Simonenko
  • Patent number: 6916613
    Abstract: The present invention is directed to methods, compositions, kits and apparatus to identify and detect the presence or absence of target analytes. The embodiments of the present invention have utility in medical diagnosis and analysis of various chemical compounds in specimens and samples, as well as the design of test kits and apparatus for implementing such methods.
    Type: Grant
    Filed: April 27, 2001
    Date of Patent: July 12, 2005
    Assignee: Q-RNA, Inc.
    Inventors: Alexander Munishkin, Abraham Grossman
  • Publication number: 20040137462
    Abstract: Methods for performing array-based hybridization assays, as well as sets of control target nucleic acids for use in the subject methods and kits comprising the same, are provided. In the subject methods, test and control sets of target nucleic acids are contacted with an array(s), where the test and control sets of target nucleic acids may or may not be labeled differentially. The subject control sets of nucleic acids contain a plurality of distinct target nucleic acids, where at least a portion of the probes on the array are represented in the control set of target nucleic acids.
    Type: Application
    Filed: June 23, 2003
    Publication date: July 15, 2004
    Inventors: Alex Chenchik, Alexander Munishkin
  • Publication number: 20030180725
    Abstract: The present invention is directed to methods, compositions, kits and apparatus to identify and detect the presence or absence of target analytes. The embodiments of the present invention have utility in medical diagnosis and analysis of various chemical compounds in specimens and samples, as well as the design of test kits and apparatus for implementing such methods.
    Type: Application
    Filed: April 27, 2001
    Publication date: September 25, 2003
    Applicant: Q-RNA, INC.
    Inventors: Alexander Munishkin, Abraham Grossman
  • Publication number: 20020160360
    Abstract: Long oligonucleotide arrays, as well as methods for their preparation and use in hybridization assays, are provided. The subject arrays are characterized in that at least a portion of the probes of the array, and usually all of the probes of the array, are long oligonucleotides, e.g. oligonucleotides having a length of from about 50 to 120 nt. Each long oligonucleotide probe on the array is preferably chosen to exhibit substantially the same high target binding efficiency and substantially the same low non-specific binding under conditions in which the array is employed. The subject arrays find use in a number of different applications, e.g. differential gene expression analysis.
    Type: Application
    Filed: November 15, 1999
    Publication date: October 31, 2002
    Inventors: ALEX CHENCHIK, ALEXANDER MUNISHKIN, PETER SIMONENKO
  • Patent number: 6225058
    Abstract: The present invention is directed to methods, compositions, kits and apparatus to identify and detect the presence or absence of target analytes. The embodiments of the present invention have utility in medical diagnosis and analysis of various chemical compounds in specimens and samples, as well as the design of test kits and apparatus for implementing such methods.
    Type: Grant
    Filed: January 13, 1999
    Date of Patent: May 1, 2001
    Assignee: InVitro Diagnostics, Inc.
    Inventors: Alexander Munishkin, Abraham Grossman