Abstract: The present invention relates to complement component 1s (C1S) inhibitors for use in treatment of neurological diseases. The invention in particular relates to the use of C1S inhibitors for down-regulation of C1S expression. The invention also relates to nucleic acid molecules, which are complementary to C1S and capable of reducing the level of an C1S mRNA. Also comprised in the present invention is a pharmaceutical composition and its use in the treatment of neurological diseases.

Abstract: The present invention relates to complement C1r subcomponent (C1R) inhibitors for use in treatment of neurological diseases. The invention in particular relates to the use of C1R inhibitors for down-regulation of C1R expression. The invention also relates to nucleic acid molecules, which are complementary to C1R and capable of reducing the level of an C1R mRNA. Also comprised in the present invention is a pharmaceutical composition and its use in the treatment of neurological diseases.

Abstract: The present invention relates to complement component 4 (C4) inhibitors for use in treatment of a neurological disease. The invention in particular relates to the use of C4 inhibitors for down-regulation of C4 expression. The invention also relates to nucleic acid molecules, which are complementary to C4A and/or C4B and capable of reducing the level of an C4A and/or C4B mRNA. Also comprised in the present invention is a pharmaceutical composition and its use in the treatment of a neurological disease.

Abstract: A system enables tool to process remote log files as if the log files were located locally. The system relies on technology, such a file system in user space (FUSE), to add log file search results to the local file system. In some embodiments, the log file search results are associated with virtual files in the local file system. A remote data store system communicates with the local system to provide the search results in response to a search query.

Abstract: A system enables tool to process remote log files as if the log files were located locally. The system relies on technology, such a file system in user space (FUSE), to add log file search results to the local file system. In some embodiments, the log file search results are associated with virtual files in the local file system. A remote data store system communicates with the local system to provide the search results in response to a search query.

Abstract: A data intake and query system provides interfaces that enable users to configure source type definitions used by the system. A data intake and query system generally refers to a system for collecting and analyzing data including machine-generated data. Such a system may be configured to consume many different types of machine data generated by any number of different data sources including various servers, network devices, applications, etc. At a high level, a source type definition comprises one or more properties that define how various components of a data intake and query system collect, index, store, search and otherwise interact with particular types of data consumed by the system. The interfaces provided by the system generally comprise one or more interface components for configuring various attributes of a source type definition.