Patents by Inventor Alexander N. Marziale

Alexander N. Marziale has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ASYMMETRIC CATALYTIC DECARBOXYLATIVE ALKYL ALKYLATION USING LOW CATALYST CONCENTRATIONS AND A ROBUST PRECATALYST
    Publication number: 20190055182
    Abstract: This invention provides efficient and scalable enantioselective methods that yield 2-alkyl-2-allylcycloalkyanone compounds with quaternary stereogenic centers. Methods include the method for the preparation of a compound of formula (I): comprising treating a compound of formula (II) or (III): with a palladium (II) catalyst under alkylation conditions.
    Type: Application
    Filed: October 22, 2018
    Publication date: February 21, 2019
    Inventors: Brian M. Stoltz, Alexander N. Marziale, Robert A. Craig, Douglas Duquette, Kelly E. Kim, Marc Liniger, Yoshitaka Numajiri
  • Asymmetric catalytic decarboxylative alkyl alkylation using low catalyst concentrations and a robust precatalyst
    Patent number: 10106479
    Abstract: This invention provides efficient and scalable enantioselective methods that yield 2-alkyl-2-allylcycloalkyanone compounds with quaternary stereogenic centers. Methods include the method for the preparation of a compound of formula (I): comprising treating a compound of formula (II) or (III): with a palladium (II) catalyst under alkylation conditions.
    Type: Grant
    Filed: March 25, 2016
    Date of Patent: October 23, 2018
    Assignee: California Institute of Technology
    Inventors: Brian M. Stoltz, Alexander N. Marziale, Robert A. Craig, Douglas Duquette, Kelly E. Kim, Marc Liniger, Yoshitaka Numajiri
  • ASYMMETRIC CATALYTIC DECARBOXYLATIVE ALKYL ALKYLATION USING LOW CATALYST CONCENTRATIONS AND A ROBUST PRECATALYST
    Publication number: 20160280623
    Abstract: This invention provides efficient and scalable enantioselective methods that yield 2-alkyl-2-allylcycloalkyanone compounds with quaternary stereogenic centers. Methods include the method for the preparation of a compound of formula (I): comprising treating a compound of formula (II) or (III): with a palladium (II) catalyst under alkylation conditions.
    Type: Application
    Filed: March 25, 2016
    Publication date: September 29, 2016
    Inventors: Brian M. Stoltz, Alexander N. Marziale, Robert A. Craig, Douglas Duquette, Kelly E. Kim, Marc Liniger, Yoshitaka Numajiri