Patents by Inventor Alexander Nesterov-Mueller

Alexander Nesterov-Mueller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ultra high-density oligomer arrays and method of production thereof
    Patent number: 10376858
    Abstract: The present invention relates to a method of producing an oligomer array. The invention comprises the steps of: providing a substrate with a multitude of recesses; introducing a first particle with a first molecule into a recess; releasing the first molecule from the first particle; binding the first molecule to a second molecule to form an oligomer while immobilizing the second molecule in the recess; optionally repeating the steps, wherein at least one of the first particles and/or the first molecules comprises a detectable marker.
    Type: Grant
    Filed: April 12, 2018
    Date of Patent: August 13, 2019
    Assignee: KARLSRUHER INSTITUT FUER TECHNOLOGIE
    Inventors: Alexander Nesterov-Mueller, Valentina Bykovskaya, Clemens Matthias von Bojnicic-Kninski, Felix Friedrich Loeffler, Roman Popov, Barbara Ridder, Frank Breitling, Daniela Silke Althuon
  • ULTRA HIGH-DENSITY OLIGOMER ARRAYS AND METHOD OF PRODUCTION THEREOF
    Publication number: 20180229204
    Abstract: The present invention relates to a method of producing an oligomer array. The invention comprises the steps of: providing a substrate with a multitude of recesses; introducing a first particle with a first molecule into a recess; releasing the first molecule from the first particle; binding the first molecule to a second molecule to form an oligomer while immobilizing the second molecule in the recess; optionally repeating the steps, wherein at least one of the first particles and/or the first molecules comprises a detectable marker.
    Type: Application
    Filed: April 12, 2018
    Publication date: August 16, 2018
    Applicant: Karlsruher Institut fuer Technologie
    Inventors: Alexander Nesterov-Mueller, Valentina Bykovskaya, Clemens Matthias von Bojnicic-Kninski, Felix Friedrich Loeffler, Roman Popov, Barbara Ridder, Frank Breitling, Daniela Silke Althuon
  • Method for combinatorial particle manipulation for producing high-density molecule arrays, in particular peptide arrays, and molecule arrays that can be obtained by means thereof
    Patent number: 9925509
    Abstract: The present invention relates to a method for combinatorial particle manipulation for producing high-density molecule arrays, and to the high-density molecule arrays obtained therefrom. In particular, the present invention relates to a method for producing high-density molecule arrays, in particular peptide or oligonucleotide arrays, by combinatorial patterning of particles, wherein the patterning is achieved by the selective and direct action of electromagnetic radiation.
    Type: Grant
    Filed: April 17, 2014
    Date of Patent: March 27, 2018
    Assignee: PEPperPRINTGmbH (DE/DE)
    Inventors: Frieder Märkle, Alexander Nesterov-Müller, Frank Breitling, Felix Löffler, Sebastian Schillo, Valentina Bykovskaya, Clemens Von Bojnicic-Kninski, Klaus Leibe
  • METHOD FOR COMBINATORIAL PARTICLE MANIPULATION FOR PRODUCING HIGH-DENSITY MOLECULE ARRAYS, IN PARTICULAR PEPTIDE ARRAYS, AND MOLECULE ARRAYS THAT CAN BE OBTAINED BY MEANS THEREOF
    Publication number: 20160082406
    Abstract: The present invention relates to a method for combinatorial particle manipulation for producing high-density molecule arrays, and to the high-density molecule arrays obtained therefrom. In particular, the present invention relates to a method for producing high-density molecule arrays, in particular peptide or oligonucleotide arrays, by combinatorial patterning of particles, wherein the patterning is achieved by the selective and direct action of electromagnetic radiation.
    Type: Application
    Filed: April 17, 2014
    Publication date: March 24, 2016
    Inventors: Frieder MÄRKLE, Alexander NESTEROV-MÜLLER, Frank BREITLING, Felix LÖFFLER, Sebastian SCHILLO, Valentina BYKOVSKAYA, Clemens VON BOJNICIC-KNINSKI, Klaus LEIBE