Abstract: Microfluidic devices having an electrowetting configuration and an optimized droplet actuation surface are provided. The devices include a conductive substrate having a dielectric layer, a hydrophobic layer covalently bonded to the dielectric layer, and a first electrode electrically coupled to the dielectric layer and configured to be connected to a voltage source. The microfluidic devices also include a second electrode configured to be connected to the voltage source. The hydrophobic layer features self-associating molecules covalently bonded to a surface of the dielectric layer in a manner that produces a densely-packed monolayer that resists intercalation and or penetration by polar molecules or species.

Abstract: Optical assemblies for use in medical or other devices so as to image an object under examination onto an image sensor include a plurality of lens elements that can be retained in lens barrel. The lens elements and the lens barrel can be sealed with a compressible gasket. In one example, at least one lens element is made of an injection-moldable plastic and at least one lens element is made of a relatively dispersive optical glass. A lens barrel diameter or lens diameter can be selected to permit access to the object under examination with surgical or other tools. Aperture plates can be situated so as to reduce flare in the object image.

Abstract: Optical assemblies for use in medical or other devices so as to image an object under examination onto an image sensor include a plurality of lens elements that can be retained in lens barrel. The lens elements and the lens barrel can be sealed with a compressible gasket. In one example, at least one lens element is made of an injection-moldable plastic and at least one lens element is made of a relatively dispersive optical glass. A lens barrel diameter or lens diameter can be selected to permit access to the object under examination with surgical or other tools. Aperture plates can be situated so as to reduce flare in the object image.

Abstract: Optical assemblies for use in medical or other devices so as to image an object under examination onto an image sensor include a plurality of lens elements that can be retained in lens barrel. The lens elements and the lens barrel can be sealed with a compressible gasket. In one example, at least one lens element is made of an injection-moldable plastic and at least one lens element is made of a relatively dispersive optical glass. A lens barrel diameter or lens diameter can be selected to permit access to the object under examination with surgical or other tools. Aperture plates can be situated so as to reduce flare in the object image.

Abstract: Optical assemblies for use in medical or other devices so as to image an object under examination onto an image sensor include a plurality of lens elements that can be retained in lens barrel. The lens elements and the lens barrel can be sealed with a compressible gasket. In one example, at least one lens element is made of an injection-moldable plastic and at least one lens element is made of a relatively dispersive optical glass. A lens barrel diameter or lens diameter can be selected to permit access to the object under examination with surgical or other tools. Aperture plates can be situated so as to reduce flare in the object image.