Abstract: A method for forming fluorite from a F?-containing aqueous fluid, the method comprising: contacting a bioactive glass comprising calcium with the F?-containing aqueous fluid; and forming the fluorite. A filter media, and filter containing the filter media, for forming fluorite from a F?-containing aqueous fluid, the filter media comprising: a bioactive glass comprising calcium; and at least one of sand, gravel, charcoal, polymer particles, and ceramic particles.

Abstract: A glass composition includes: greater than or equal to about 70 mol % and less than or equal to about 90 mol % SiO2; greater than or equal to about 2 mol % and less than or equal to about 9 mol % Al2O3; greater than or equal to about 5 mol % and less than or equal to about 15 mol % Li2O; greater than or equal to about 0 mol % and less than or equal to about 10 mol % Y2O3; greater than or equal to about 0 mol % and less than or equal to about 9 mol % Ta2O5; greater than or equal to about 0 mol % and less than or equal to about 10 mol % La2O3; and greater than or equal to about 0.05 mol % and less than or equal to about 1 mol % SnO2. The sum of Y2O3, Ta2O5, and La2O3 may be greater than or equal to about 2 mol % and less than or equal to about 15 mol %.

Abstract: Non-human animal cells and non-human animals comprising a humanized Cacng1 locus and methods of using such non-human animal cells and non-human animals are provided. Non-human animal cells or non-human animals comprising a humanized Cacng1 locus express a human CACNG1 protein or fragments thereof.

Abstract: Non-human animals, and methods and compositions for making and using the same, are provided, wherein the non-human animals comprise a humanization of a Lymphocyte activation gene 3 (Lag3). The non-human animals may be described, in some embodiments, as having a genetic modification to an endogenous Lag3 locus so that the non-human animals express a Lag3 polypeptide that includes a human portion and an endogenous portion (e.g., a non-human portion).

Abstract: A method of determining haematocrit or haemoglobin concentration of a blood sample comprises calculating, based on a plurality of complex capacitance values of the blood sample, a complex capacitance at a predetermined imaginary component value, each of the plurality of complex capacitance values of the blood sample having a corresponding frequency; and determining the haematocrit or haemoglobin concentration based on the calculated complex capacitance or a real component of the calculated complex capacitance.

Abstract: Non-human animals, and methods and compositions for making and using the same, are provided, wherein the non-human animals comprise a humanization of a Lymphocyte activation gene 3 (Lag3). The non-human animals may be described, in some embodiments, as having a genetic modification to an endogenous Lag3 locus so that the non-human animals express a Lag3 polypeptide that includes a human portion and an endogenous portion (e.g., a non-human portion).

Abstract: Non-human animals, and methods and compositions for making and using the same, are provided, wherein the non-human animals comprise a humanization of a Programmed cell death 1 (Pdcd1) gene. The non-human animals, in some embodiments, comprise a genetic modification to an endogenous Pdcd1 gene so that the non-human animals express a PD-1 polypeptide that includes a human portion and an endogenous portion (e.g., a non-human portion).

Abstract: Methods of recovering lithium from glass include crushing the glass to produce glass particles and contacting the glass particles with an aqueous leaching solution at a leaching temperature greater than ambient temperature and less than the boiling temperature of the aqueous leaching solution to produce a leachate slurry. The glass particles include lithium. The aqueous leaching solution includes sulfuric acid in water or sodium hydroxide in water. Contacting the glass particles with the aqueous leaching solution leaches greater than or equal to about 50% of the lithium out of the glass particles. The methods further comprise separating the leachate slurry to produce a solid residue and a leachate, the leachate comprising the lithium leached from the glass particles. The method further include recovering the lithium from the leachate through precipitation.

Abstract: A method for extracting lithium metal ions from glass includes contacting the glass with a molten salt bath for a duration of time, wherein the glass includes lithium and the contacting the glass with the molten salt bath for the duration of time extracts at least 40% of the lithium metal ions from the glass. The method further includes removing residual solids from the molten salt bath, wherein the residual solids include residual glass having a reduced concentration of lithium. The method further includes precipitating lithium metal ions from the molten salt bath to produce a solid precipitated lithium salt and separating the precipitated lithium salt from the molten salt bath.

Abstract: A process for recovering lithium from lithium-containing glass based materials includes providing lithium-containing particles comprising the lithium-containing glass-based materials; contacting the lithium-containing particles with calcium salts in water, wherein the contacting causes leaching of at least a portion of lithium ions from the lithium-containing particles into a first leachate of the first mixture; separating the first mixture into the first leachate and a first residue; and recovering lithium from the first leachate.

Abstract: Compositions and methods are provided for modifying a rat genomic locus of interest using a large targeting vector (LTVEC) comprising various endogenous or exogenous nucleic acid sequences as described herein. Compositions and methods for generating a genetically modified rat comprising one or more targeted genetic modifications in their germline are also provided. Compositions and methods are provided which comprise a genetically modified rat or rat cell comprising a targeted genetic modification in the rat interleukin-2 receptor gamma locus, the rat ApoE locus, the rat Rag2 locus, the rat Rag1 locus and/or the rat Rag2/Rag1 locus. The various methods and compositions provided herein allows for these modified loci to be transmitted through the germline.

Abstract: A method of regenerating a lithium-poisoned molten salt bath is provided. The method includes contacting glass particulates with the molten salt bath such that poisoning ions are exchanged from the bath into the glass. The glass compositions utilized in the method are also provided.

Abstract: Systems and methods for supplying electrical power between two electric energy storage devices are disclosed. In one example, an electric isolation switch is held open after engine starting until a voltage of a first electric energy storage device and a voltage of a second electric energy storage device are within a threshold voltage of at least one predetermined voltage level.

Abstract: Genetically modified rodents such as mice and rats, and methods and compositions for making and using the same, are provided. The rodents comprise a humanization of at least one endogenous rodent Tmprss gene, such as an endogenous rodent Tmprss2, Tmprss4, or Tmprss11d gene.

Abstract: A deformable array of semiconductor devices, and a method of manufacturing such a deformable array. The deformable array comprises a plurality of islands, where each island contains at least one semiconductor device, and the plurality of islands are arranged in an auxetic geometry.

Abstract: Genetically modified rodents such as mice and rats, and methods and compositions for making and using the same, are provided. The rodents comprise a humanization of at least one endogenous rodent Tmprss gene, such as an endogenous rodent Tmprss2, Tmprss4, or Tmprss11d gene.

Abstract: A system for measuring fluid absorption and retention properties of various samples having one or more materials, layers and/or articles. The system includes an optically or radiographically transparent fixture. The system enables measuring voxels having a grayscale value that demonstrate a difference in fluid densities and thereby enable the study of fluid flow and movement within and/or amongst various materials and articles in real time.

Abstract: Non-human animal cells and non-human animals comprising a humanized Asgr1 locus and methods of using such non-human animal cells and non-human animals are provided. Non-human animal cells or non-human animals comprising a humanized Asgr1 locus express a human ASGR1 protein or an Asgr1 protein, fragments of which are from human ASGR1. Methods are provided for using such non-human animals comprising a humanized Asgr1 locus to assess in vivo efficacy of human-ASGR1-mediated delivery of therapeutic molecules or therapeutic complexes to the liver and to assess the efficacy of therapeutic molecules or therapeutic complexes acting via human-ASGR1-mediated mechanisms.

Abstract: Methods and systems are provided for controlling an engine idle-stop based on upcoming traffic and road conditions. In one example, a method may include receiving data including traffic information and road characteristics immediately ahead of a vehicle from one or more remote sources, and adjusting one or more vehicle thresholds based on the received data. A duration of a prospective engine idle-stop may be estimated based on the received data and an engine idle-stop may be initiated based on the duration of the prospective engine idle-stop and the adjusted one or more vehicle threshold.

Abstract: Methods, systems, and apparatuses are provided for a vehicle tethered by a hitch to a trailer. The method includes generating sensor data from one or more sensors that are responsive to forces applied to the hitch by a vehicle mechanically coupled to the hitch; receiving sensor data to compute a direction for the guidance of the trailer; monitoring a set of parameters reflecting forces in a lateral and traverse direction derived from data generated by the sensors wherein the set of parameters include at least one parameter of a magnitude of force, and at least one parameter of the direction of force acting upon the hitch; and calculating at least a rate-of-change of the magnitude of force and direction over time to determine a trajectory for the trailer that enables the trailer to follow the lead vehicle without a tractive effort of the lead vehicle.