Patents by Inventor Alexander Or

Alexander Or has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PATTERNING USING MONOMER BASED SACRIFICIAL MATERIAL LIFTOFF
    Publication number: 20240412973
    Abstract: A method includes forming a plurality of islands of first material on a plurality of first sections of a layer. A plurality of second sections of the layer are not covered by the first material. The method further includes depositing a second material on (i) the islands of first material and (ii) the second sections of the layer that are not covered by the islands of first material. The method further includes evaporating and/or sublimating the islands of first material and removing remnants of the second material that were on the islands of the first material. In an example, the second material remains on the second sections of the layer, to thereby form a pattern of the second material on the layer. In an example, the first material is a monomer, and the second material is a conductor or a dielectric or a semiconductor.
    Type: Application
    Filed: June 6, 2023
    Publication date: December 12, 2024
    Applicant: BAE SYSTEMS Information and Electronic Systems Integration Inc.
    Inventors: Nathaniel P. Wyckoff, Benjamin Terry, Alexander S. Warren
  • LIPOPHILIC SIRNA CONJUGATES FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISEASES
    Publication number: 20240409938
    Abstract: Disclosed herein are methods of treating central nervous system diseases, such as Alzheimer's disease and Huntington's disease, using lipophilic siRNA conjugates that can bind to albumin. The disclosed methods can advantageously provide widespread, long-term gene silencing in the central nervous system. An example method includes administering to a subject an effective amount of a conjugate, optionally in combination with a pharmaceutically acceptable excipient, wherein the conjugate includes a siRNA capable of inhibiting expression of a protein associated with the central nervous system disease; a lipophilic ligand capable of binding albumin; and a linker attaching the siRNA to the lipophilic ligand, the linker including a branching molecule attached to the siRNA, and a hydrophilic spacer attaching the branching molecule to the lipophilic ligand.
    Type: Application
    Filed: June 7, 2024
    Publication date: December 12, 2024
    Inventors: Craig L. Duvall, Ethan S. Lippmann, Alexander G. Sorets
  • SEPARATION SYSTEM AND METHOD FOR SEPARATING AND PURIFYING A TARGET COMPONENT
    Publication number: 20240408513
    Abstract: A separation system for separating and purifying a target component, a method for separating and purifying a target component, and the use of a crossflow diafiltration unit for processing a target phase. The system includes an aqueous-two phase extraction unit for aqueous-two phase extraction of the fluid, a separation unit for separating a target phase, and a crossflow diafiltration unit.
    Type: Application
    Filed: October 13, 2022
    Publication date: December 12, 2024
    Applicant: Sartorius Stedim Biotech GmbH
    Inventors: Thomas Kruse, Markus Kampmann, Alexander Helling, Martin Leuthold
  • RIGIDIZING OVERTUBE
    Publication number: 20240408352
    Abstract: A rigidizing device includes an elongate flexible tube, a braid layer positioned over the elongate flexible tube, an outer layer over the flexible tube and the braid layer, and an inlet between the elongate flexible tube and the outer layer and configured to attach to a source of vacuum or pressure. The braid layer has a plurality of strands braided together at a braid angle of 5-40 degrees relative to a longitudinal axis of the elongate flexible tube when the elongate flexible tube is straight. The rigidizing device is configured to have a rigid configuration when vacuum or pressure is applied through the inlet and a flexible configuration when vacuum or pressure is not applied through the inlet. The braid angle is configured to change as the rigidizing device bends when the rigidizing device is in the flexible configuration.
    Type: Application
    Filed: August 20, 2024
    Publication date: December 12, 2024
    Inventors: Alexander Q. TILSON, Stephen J. MORRIS, Garrett J. GOMES, Adam S. WIGGINTON, Mark C. SCHEEFF, Charles S. LOVE
  • Transformer Based Neural Network Using Variable Auxiliary Input
    Publication number: 20240414361
    Abstract: A method of processing a current object is provided. A set of input data tensors representing the current object are inputted into a first neural layer of a transformer based neural network. Based on information about processing the current object, at least one auxiliary data tensor is inputted into the first neural layer or a second neural layer of the transformer based neural network, where the at least one auxiliary data tensor is different from each of the input data tensors of the set of input data tensors and represents at least one auxiliary input. The set of input data tensors are processed by the transformer based neural network using the at least one auxiliary data tensor in order to obtain a set of output data tensors.
    Type: Application
    Filed: June 14, 2024
    Publication date: December 12, 2024
    Inventors: Georgii Petrovich Gaikov, Sergey Yurievich Ikonin, Ahmet Burakhan Koyuncu, Alexander Alexandrovich Karabutov, Timofey Mikhailovich Solovyev, Elena Alexandrovna Alshina
  • PERFORATED TISSUE MATRIX
    Publication number: 20240408277
    Abstract: The present disclosure relates to tissue matrix products. The products can includes tissue matrices that have holes or perforations located at certain positions to improve certain in vivo functions without substantial loss of strength or other important properties.
    Type: Application
    Filed: April 22, 2024
    Publication date: December 12, 2024
    Inventor: Alexander Ringo
  • MACHINE LEARNING SOLUTIONS FOR MATCHING OF VEHICLE EXIT TO UNMATCHED ENTRY EVENTS
    Publication number: 20240412634
    Abstract: An edge device generates an exit event for a vehicle exiting a parking facility. The edge device determines whether the exit event matches with an entry event. Responsive to determining that the exit event does not match to an entry event, the edge device inputs images of the vehicle into a supervised machine learning model and receives, as output from the model, an exit feature vector. The edge device retrieves entry feature vectors corresponding to hanging entry events. A hanging entry event is an entry event for a vehicle with an unknown vehicle identifier. Edge device inputs the exit feature vector and the entry feature vectors into an unsupervised machine learning model and receives, as output from the model, matching scores for each entry feature vector. Edge device matches the exit event to one of the hanging entry events based on the matching scores.
    Type: Application
    Filed: June 6, 2023
    Publication date: December 12, 2024
    Inventors: Ji Sung Hwang, Anil Kumar Nayak, Barry James O’Brien, Kaleb-John Seijin Loo, Alexander David Israel
  • MULTISPECIFIC BINDING AGENTS AGAINST PD-L1 AND CD137 IN COMBINATION WITH ANTI PD-1 ANTIBODIES FOR TREATING CANCERS
    Publication number: 20240409653
    Abstract: The present disclosure relates to combination therapy using a binding agent that binds to human PD-L1 and to human CD 13 7 in combination with pembrolizumab to reduce or prevent progression of a tumor or treating cancer.
    Type: Application
    Filed: October 5, 2022
    Publication date: December 12, 2024
    Inventors: Alexander MUIK, Kristina NÜRMBERGER, Nora PENCHEVA, Maria N. JURE-KUNKEL, Ugur SAHIN
  • SECURED ACCESS TO IN-VEHICLE END NODES AND WAYS TO ENHANCE VEHICLE FUNCTIONALITY
    Publication number: 20240414527
    Abstract: The present disclosure relates to an in-vehicle network end node and secure ways for the in-vehicle end node to access a server in order to off-load complex tasks from the in-vehicle end node thereby enhancing its function despite the scarce resources of the in-vehicle end node.
    Type: Application
    Filed: June 12, 2023
    Publication date: December 12, 2024
    Inventors: Alexander ZEH, Thomas LIEBETRAU
  • METHODS AND SYSTEMS FOR TUMOUR MONITORING
    Publication number: 20240412813
    Abstract: The present invention provides a computer-implemented method for estimating the cancer cell fraction (CCF) of at least one tumour-specific mutation in a subject. Also provided are related methods for monitoring the clonal dynamics of a tumour, monitoring a treatment of the tumour and methods for treating a subject having a cancer, as well as systems for implementing the methods of the invention.
    Type: Application
    Filed: October 7, 2022
    Publication date: December 12, 2024
    Applicant: Cancer Research Technology Limited
    Inventors: Alexander Mark Frankell, Christopher Abbosh, Robert Charles Swanton
  • Communication of Payload Data Through Altered Sequence of Metadata Defining Audio-Rendering Directives
    Publication number: 20240412748
    Abstract: To facilitate communicating payload data to a destination, a computing system varies audio-rendering-directive metadata over time in a manner that represents the payload data and outputs the varied audio-rendering-directive metadata over time for communication along with an audio stream to the destination to facilitate rendering of the audio stream at the destination in accordance with the varied audio-rendering-directive metadata over time. The rendering of the audio stream at the destination conveys the payload data by being in accordance with the varied audio-rendering-directive metadata over time that represents the payload data. Thus, an audio meter operating at the destination could detect associated variation in the rendered audio stream and map that detected variation in the rendered audio stream to the payload data, thereby receiving the payload data.
    Type: Application
    Filed: June 7, 2023
    Publication date: December 12, 2024
    Inventors: Alexander Topchy, Justin Dan Mathew, Jeremey M. Davis, Vladimir Kuznetsov
  • TECHNOLOGIES FOR CONTENT ANALYSIS
    Publication number: 20240412550
    Abstract: Various computing technologies for content analysis.
    Type: Application
    Filed: March 1, 2024
    Publication date: December 12, 2024
    Inventors: Roman Tsibulevskiy, Barry Greenbaum, Alexander Ivakhnenko
  • CONFIGURABLE MULTI-CLASS PASSENGER SEAT ASSEMBLY
    Publication number: 20240409218
    Abstract: A passenger seat assembly includes a first seat, a second seat, and a center console. In embodiments, a privacy divider is positioned atop the center console and serves as a mounting location for amenities for serving the first and second passenger seats. The center console is configurable to include various privacy, comfort, and utility features depending on the intended seating class for the passenger seat assembly. In embodiments, the first and second passenger seats include headrests and privacy assemblies associated with the headrests for enhancing privacy between the seats and/or relative to adjacent aisles.
    Type: Application
    Filed: June 5, 2024
    Publication date: December 12, 2024
    Inventors: Michael Princip, Alexander Velet, Charles Martin Hansson, Travis Vaninetti, Daniel Mills, James Kash, Ferhad Tabakovic, Travis Finlay, Brian Green
  • Communication of Payload Data Through Altered Sequence of Metadata Defining Audio-Rendering Directives
    Publication number: 20240414490
    Abstract: To facilitate communicating payload data to a destination, a computing system varies audio-rendering-directive metadata over time in a manner that represents the payload data and outputs the varied audio-rendering-directive metadata over time for communication along with an audio stream to the destination to facilitate rendering of the audio stream at the destination in accordance with the varied audio-rendering-directive metadata over time. The rendering of the audio stream at the destination conveys the payload data by being in accordance with the varied audio-rendering-directive metadata over time that represents the payload data. Thus, an audio meter operating at the destination could detect associated variation in the rendered audio stream and map that detected variation in the rendered audio stream to the payload data, thereby receiving the payload data.
    Type: Application
    Filed: June 7, 2023
    Publication date: December 12, 2024
    Inventors: Alexander Topchy, Justin Dan Mathew, Jeremey M. Davis, Vladimir Kuznetsov
  • EFFICIENT AND SECURED ACCESS TO IN-VEHICLE END NODES ACROSS A VEHICLE FLEET
    Publication number: 20240414234
    Abstract: The present disclosure relates to a server, a relay, and an in-vehicle end node that enable an efficient deployment of software updates for in-vehicle network end nodes.
    Type: Application
    Filed: August 2, 2024
    Publication date: December 12, 2024
    Inventor: Alexander ZEH
  • CUPHOLDER SYSTEM FOR A VEHICLE
    Publication number: 20240409017
    Abstract: A cupholder system for a vehicle includes: a cupholder assembly comprising a first cupholder opening; a lid configured to, when in a closed position, cover at least the first cupholder opening, and when in an open position, uncover the first cupholder opening; and an actuation system configured to, in dependence on an electrical signal, deploy the lid in a first path to the open position and deploy the cupholder assembly in a second path from a stowed position to a deployed position.
    Type: Application
    Filed: October 10, 2022
    Publication date: December 12, 2024
    Inventors: Henry VYSKOCIL, Spencer GREENING, John DUTTON, Alexander GRAY, Luke TIGHE, Brett TOWNSEND, John HEATH, Andy POLSON, Ben PHYALL, Sam SOAR, Joseph WHARTON
  • 5,6-FUSED AND 6,6-FUSED BICYCLIC ALCOHOLS AND ETHERS AND COMPOSITIONS FOR USE AS 15-PROSTAGLANDIN DEHYDROGENASE MODULATORS
    Publication number: 20240409557
    Abstract: The present disclosure provides novel 15-hydroxy-prostaglandin dehydrogenase inhibitors, pharmaceutical compositions comprising such compounds, and methods of using such compounds and compositions in treating 15-hydroxy-prostaglandin dehydrogenase-mediated disease. Also provided are methods of making such compounds and intermediates thereof. The compounds have a general Formula (A). Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula (A).
    Type: Application
    Filed: May 7, 2024
    Publication date: December 12, 2024
    Applicant: AMGEN INC.
    Inventors: Kevin Lloyd GREENMAN, Alexander J. Pickrell, Kexue LI, Albert K. AMEGADZIE, Hui-Ling WANG, Nicholas Anthony WEIRES, John G. ALLEN, Matthew P. BOURBEAU
  • IONIC LIQUIDS FOR DRUG DELIVERY
    Publication number: 20240408180
    Abstract: The technology described herein is directed to ionic liquids and methods of drug delivery.
    Type: Application
    Filed: October 7, 2022
    Publication date: December 12, 2024
    Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Samir MITRAGOTRI, Jayoung KIM, Alexander M. CURRERI
  • SUCTION ACTUATED ELECTROCAUTERY AND SUCTION DEVICE
    Publication number: 20240407825
    Abstract: An electrocautery device with a retractable suction tube is described. The electrocautery device includes a suction tube assembly that can move between an extended or retracted position using vacuum force generated by a suction source. In some embodiments, the suction tube assembly automatically locks into the extended position when extended such that axial force cannot cause the suction tube assembly to retract. The device may be suitable for use in laparoscopic procedures. The suction tube may be coaxially aligned with the electrocautery tip.
    Type: Application
    Filed: August 15, 2024
    Publication date: December 12, 2024
    Applicant: Children's Medical Center Corporation
    Inventors: Heung Bae Kim, Gabriel J. Ramos-Gonzalez, Alexander Yang
  • Improved Thermal and Electrical Conductivity Between Metal Contacts
    Publication number: 20240410939
    Abstract: In one example, a system includes a semiconductor package having a metal contact. The system includes a metal submount. The metal submount includes a plurality of spring pin connectors embedded in the metal submount, the plurality of spring pin connectors being thermally and electrically connected to one another through the metal submount. The metal contact of the semiconductor package is thermally and electrically coupled to the metal submount through the plurality of spring pin connectors.
    Type: Application
    Filed: June 9, 2023
    Publication date: December 12, 2024
    Inventors: Alexander Komposch, Jason R. Fender, Eric Jacob Palsgaard, Douglas John Kroon, Matthew Kirke Mellor, Donald I. Fowlkes