Abstract: This patent document discloses assemblies and methods for removing obstructive material from a body vessel or other cavity. An assembly can include an elongate inner member, an elongate outer member, an aspirator, one or more valves, or a waste collection reservoir. Each of the elongate members can extend from a proximal end portion to a distal end portion and can include a lumen therethrough. The elongate inner member can be partially disposed in the lumen of the elongate outer member and can be moveable along its longitudinal axis relative to the elongate outer member. The aspirator can be in flow communication with the proximal end portion of the elongate inner member for drawing the obstructive material into or through its lumen. The one or more valves can be configured and positioned to allow obstructive material removed from the body vessel or cavity to be urged toward the waste collection reservoir.

Abstract: A method and apparatus, the method comprising: forming at least two electrodes (23) on a release layer wherein the at least two electrodes are configured to enable a layer of two dimensional material (25) to be provided between the at least two electrodes; providing moldable polymer (27) overlaying the at least two electrodes; wherein the at least two electrodes and the moldable polymer form at least part of a planar surface (29).

Abstract: The disclosed embodiments relate to ion delivery mechanisms, e.g., for fusion power. Particularly, some embodiments relate to systems and methods for delivering ions to a fuel source in such a manner to initiate fast ignition. The ions may be accumulated into “microbunches” and delivered to the fuel with considerable energy and velocity. The impact may compress the fuel while delivering sufficient energy to begin the fusion reaction.

Abstract: Non-human animals, and methods and compositions for making and using the same, are provided, wherein the non-human animals comprise a humanization of a Programmed cell death 1 (Pdcd1) gene. The non-human animals may be described, in some embodiments, as having a genetic modification to an endogenous Pdcd1 gene so that the non-human animals express a PD-1 polypeptide that includes a human portion and an endogenous portion (e.g., a non-human portion).

Abstract: A heat exchanger having at least one of side plates embodying a polygonal aperture through the planar base thereof, located at a predetermined position, and at least two corresponding shear-apertures located at the interface between the planar base and a first wall and a second wall of the side plate, each adjacent to the base aperture, providing at least one flexing location to accommodate thermal expansion of the heat exchanger during thermal cycling.

Abstract: Aspects of the present invention provide an approach for performing a computer program update on a target computer. In an embodiment, a target computer having a location, a user, a computer program, and a computer program update is determined. An expected install duration for installing the computer program update is determined. A social media service associated with the user is monitored. A user location is detected from the social media service and an update time window is estimated based on the user location and the distance that the user is away from the target computer location. A decision is made whether to install the computer program update based on the update time window and the expected install duration.

Abstract: A cutting head (18) for a hair cutting appliance (10) comprises a blade set (20) including a stationary blade (36) and a cutter blade (38). The stationary blade and the cutter blade comprise at least one toothed leading edge (22,24) jointly defined by respective teeth (62,64) thereof that extend in a longitudinal direction (X). The stationary blade further comprises a front face (58), at the teeth (62) thereof, arranged to face a user's skin, when in operation. A skin protector (76) couples to a housing portion (32) of the cutting head, wherein the skin protector at least partially covers the front face (58) and is arranged to contact the skin, when in operation. The skin protector is movable between a first state and a second state with respect to the blade set (20) and includes an advanced position in the first state and a retracted position in the second state.

Abstract: The present invention relates to a method of manufacturing personalized razor handles.

Abstract: An apparatus has a receiver that receives a biological response of a user to an event that occurs during a user experience. Further, the apparatus has a memory that stores one or more predefined criteria that indicate an expected biological response to the event. In addition, the apparatus has a processor that compares the biological response to the one or more predefined criteria and adjusts the user experience based at least upon the biological response failing to meet the one or more predefined criteria.

Abstract: Embodiments relate to systems and methods for providing digital dye packs in connection with a transaction via a device user interface. In an embodiment, a system includes a communication module of a remote server that interacts with a device that receives, from a user of the device, specific identifier information in connection with conducting a transaction with a recipient server; wherein the specific identifier information is associated with an alert of potential risk of the transaction. The system also includes a non-transitory memory comprising a database storing specific identifier information with corresponding actions that are executed based on the specific identifier information. The system further includes at least one hardware processor for executing an action in response to receiving corresponding identifier information associated with the alert of potential risk from the device in connection with the transaction.

Abstract: An angle of attack sensor includes a housing having an open first end and a closed second end, a heated chassis positioned within the open first end of the housing, a mounting plate positioned on the heated chassis adjacent the open first end of the housing such that an internal chamber is formed between the heated chassis and the mounting plate, a transducer compartment between the heated chassis and the closed second end of the housing, and a water management system located adjacent the internal chamber and the transducer compartment. The water management system includes an annular chamber positioned in the internal chamber, a first tube at a first end of the annular chamber, and a second tube at a second end of the annular chamber. The first tube has a hole such that the first tube is in fluid communication with the annular chamber and the internal chamber, and the second tube is in fluid communication with the annular chamber and the transducer compartment.

Abstract: An apparatus and a method for the parallel and independent operation of a normal program and a secure program on the basis of a runtime system structure have all components that are relevant to the control integrated on a hardware component with a specific hardware architecture and be isolated from one another by a runtime system structure for two dual runtime systems for making changes to non-security-relevant components without restriction. The isolation can be provided by prioritizing one of the runtime systems. Such a runtime system structure or hardware architecture eliminates the need for follow-up certification of user-programmable controllers and the certification of the security-critical component is valid even when changes to the non-security-relevant components are made.

Abstract: A security closure 5 for a container neck 40 comprises a body 25 formed from a plastics material and a metal retention member 10 formed integrally with the body 25. The metal retention member 10 remains on the container neck 40 for retaining the body 25 on the container neck 40. The metal retention member 10 makes it impossible or very difficult to remove the security closure 5 from the container neck 40 without breaking/damaging/destroying the container. The security closure 5 and a container having a container neck 40, and a method of forming the security closure 5 are also disclosed.

Abstract: Cytotoxic dimers comprising CBI-based and/or CPI-based sub-units, antibody drug conjugates comprising such dimers, and to methods for using the same to treat cancer and other conditions.

Abstract: After forming a plurality of semiconductor fins that are separated from one another by trenches on a substrate, the semiconductor fins are fully or partially oxidized to provide semiconductor oxide portions. The volume expansion caused by the oxidation of the semiconductor fins reduces widths of the trenches, thereby providing narrowed trenches for formation of epitaxial semiconductor fins using aspect ratio trapping techniques.

Abstract: An electric motor driven liquid pump, which can be used for forced lubrication of a motor vehicle manual transmission, has a housing flange-mountable on a fluid container via a flange surface. A stator including a motor winding and a magnetic rotor are incorporated in the housing for conveying liquid. The housing is formed of multiple parts including a pump housing section which has fluid inlets and outlets, a stator housing section which holds the stator and together with the pump housing section, delimits an electronics chamber in which the rotor is arranged, and a motor housing section which together with the stator housing section delimits an electronic chamber in which at least the stator is located. A sealing element seals the flange surface to the fluid container, separates the fluid chamber and the electronic chamber, and seals the latter from the environment.

Abstract: Various methods, systems, computer readable media, and graphical user interfaces (GUIs) are presented and described that enable a subject, doctor, or user to characterize or classify various types of cancer precisely. Additionally, described herein are methods, systems, computer readable media, and GUIs that enable more effective specification of treatment and improved outcomes for patients with identified types of cancer. Some embodiments of the methods, systems, computer readable media, and GUIs described herein comprise obtaining RNA expression data and/or whole exome sequencing (WES) data for biological samples; determining a respective plurality of molecular-functional (MF) profiles for a plurality of subjects; clustering the plurality of MF profiles to obtain MF profile clusters; determining a molecular-functional (MF) profile for an additional subject; and identifying, from among the MF profile clusters, a particular MF profile cluster with which to associate the MF profile for the subject.

Abstract: A device and method for reading an exposed imaging plate generate read-out light and utilize a deflection unit to direct the read-out light in a scanning movement over the imaging plate. The deflection unit has a micromirror to deflect impinging read-out light towards the imaging plate. The micromirror can swivel about a first swivel axis and about a second swivel axis distinct from the first. A detector unit detects fluorescent light emitted from the imaging plate at locations where the read-out light impinges. An evaluating unit evaluates signals received from the detector unit and builds up an image that is stored in the imaging plate. The evaluating unit takes into account, when evaluating the signals received from the detector unit, that points on the imaging plate are subjected to the read-out light variably often and/or for variable time lengths while the micromirror oscillates about the first and the second swivel axis.

Abstract: Methods and apparatus related to using document feature(s) of a document that is responsive to a query, and optionally query feature(s) of the query, to determine a presentation characteristic for presenting a search result that corresponds to the document. In some implementations, measures associated with the document feature(s) and/or query feature(s) may be used to determine the presentation characteristic. The measures may be based on past interactions, by corresponding users, with other documents that share one or more of the document features with the document, where a plurality of the other documents are different from the document (and optionally each different from one another). In some implementations, the document and/or the other documents include, or are restricted to, documents that are access restricted.

Abstract: Methods and systems are provided for controlling an engine idle-stop based on upcoming traffic and road conditions. In one example, a method may include receiving data including traffic information and road characteristics immediately ahead of a vehicle from one or more remote sources, and adjusting one or more vehicle thresholds based on the received data. A duration of a prospective engine idle-stop may be estimated based on the received data and an engine idle-stop may be initiated based on the duration of the prospective engine idle-stop and the adjusted one or more vehicle threshold.