Abstract: In an exemplary process for providing a guided consumer experience, product information comprising an image of a product is displayed. A communication session with a remote user is provided. While providing the communication session, the display of product information is adjusted using information received from the communication session. A representation of the product is displayed in computer-generated reality by capturing an image using a camera, generating a view of an environment by compositing a virtual object representing the product and the captured image, and displaying the view of the environment.

Abstract: Personnel evaluation based on crowdsourcing concepts. An approach to personnel evaluation is described that uses crowd-sourced data and an iterative approach. Individual personnel evaluators are themselves evaluated and assigned weighting factors based on their acumen and accuracy with regard to personnel evaluation. Personnel evaluations are provided by each personnel evaluator, who collectively form a crowdsourcing crowd, and weighted according to each evaluator's assigned weighting factor. The crowd-sourced weighted-averages from all evaluators are combined and used periodically and iteratively to evaluate the individual crowdsourcing participants and to re-calculate their individual weighting factors. The approach provides more accurate and more directed personnel evaluations as compared to simple arithmetic averaging of crowd-sourced data, and is improved with each iteration over time.

Abstract: An air deflection device of a motor vehicle includes an air deflection element and a displacement kinematic system. The air deflection element is displaceable by the displacement kinematic system from an extended deflection position, in which the air deflection element with a deflection surface in a front region of the air deflection element in a longitudinal direction of the motor vehicle diverts an airflow hitting the air deflection element in an underbody region in a forward direction of travel of the motor vehicle, into a retracted position. The air deflection element is displaceable by the displacement kinematic system rearwards in the longitudinal direction of the motor vehicle and upwards in a vertical direction of the motor vehicle and is pushable back in a direction of the retracted position in an event of an obstacle-related force component acting on the air deflection element in the longitudinal direction of the motor vehicle.

Abstract: A punching/perforation machine creates a predefined punching/perforation pattern in a material that is supplied in a direction of travel. The machine comprises a punching/perforation tool that includes an upper tool part which can be moved in a direction of stroke and which is equipped with a plurality of punching dies/perforation needles that are arranged in a predefined grid in a transverse direction and can be moved by a pressure beam that is operatively connected to a drive unit via a control device in order to produce a punching/perforation stroke. The material is supplied between the upper tool part and a lower tool part. The material is placed or clamped in a frame mechanism. The punching/perforation machine includes a frame accommodation/connection device for accommodating/connecting the frame mechanism, and the frame mechanism containing the material is supplied between the upper tool part and the lower tool part.

Abstract: Provided is a cabozantinib acesulfamate salt and a crystalline form thereof. Also provided are pharmaceutical compositions including the salt and crystalline form thereof, and methods of treatment of progressive, metastatic medullary thyroid cancer (MTC) or advanced renal cell carcinoma (RCC) that has been treated previously with anti-angiogenic therapy using the cabozantinib acesulfamate salt.

Abstract: A system for determining areas of discrepancy in flight for an electric aircraft is presented. The system includes a plurality of sensors, wherein each sensor is communicatively connected to a flight component and configured to detect a measured flight and generate a flight phase datum. The system further includes a computing device communicatively connected to the plurality of sensors, wherein the computing device is configured to determine, by a flight phase machine-learning model, a flight phase discrepancy datum. The computing device is configured to train the flight phase machine-learning using a flight phase training set, wherein the flight phase training set correlates a flight phase to a flight standard and output the flight phase discrepancy datum. The computing device is further configured to identify an anomalous performance phase as a function of the flight phase discrepancy datum and generate a discrepancy response.

Abstract: A display comprises a transparent polymer support, an array of light emitters embedded in the support, and a redistribution layer. Each light emitter comprises electrode contacts that are substantially coplanar with a back surface of the support and emits light through a front surface of the support opposite the back surface when provided with power through the electrode contacts. The redistribution layer comprises a dielectric layer that is disposed on and in contact with the support back surface and distribution contacts that extend through the dielectric layer. Each of the distribution contacts is electrically connected to an electrode contact and is at least partially exposed.

Abstract: Mechanical circulatory supports configured to operate in series with the native heart are disclosed. In an embodiment, a centrifugal pump is used. In an embodiment, inlet and outlet ports are connected into the aorta and blood flow is diverted through a lumen and a centrifugal pump between the inlet and outlet ports. The supports may create a pressure rise between about 40-80 mmHg, and maintain a flow rate of about 5 L/min. The support may be configured to be inserted in a collinear manner with the descending aorta. The support may be optimized to replicate naturally occurring vortex formation within the aorta. Diffusers of different dimensions and configurations, such as helical configuration, and/or the orientation of installation may be used to optimize vortex formation. The support may use an impeller which is electromagnetically suspended, stabilized, and rotated to pump blood.

Abstract: A system for visual inspection, which includes a processor that receives a sensitivity level relating to an image of an item on an inspection line, the image being displayed on the user interface device, and calculates a minimal defect size visible in the image at the received sensitivity level. The calculated minimal defect size is then displayed on a user interface. This visual demonstration of minimal detectable size, which changes as the user changes sensitivity level, enables the user to easily obtain a desired minimal detectable defect size.

Abstract: Apparatus, systems, and methods for acoustic transmission via tubular are provided. A transceiver comprises a piezoelectric transducer; a switch coupled to the piezoelectric transducer; a charge mode receiver coupled to the switch; and a transmitter coupled to the switch.

Abstract: A system can include one or more processors; memory; a data interface that receives data; a control interface that transmits control signals for control of pumps of a hydraulic fracturing operation; and one or more components that can include one or more of a modeling component that predicts pressure in a well fluidly coupled to at least one of the pumps, a pumping rate adjustment component that generates a pumping rate control signal for transmission via the control interface, a capacity component that estimates a real-time pumping capacity for each individual pump, and a control component that, for a target pumping rate for the pumps during the hydraulic fracturing operation, generates at least one of engine throttle and transmission gear settings for each of the individual pumps using an estimated real-time pumping capacity for each individual pump where the settings are transmissible via the control interface.

Abstract: An inkjet printer is disclosed that has a substrate support; a calibration module disposed adjacent to the substrate support and comprising a stage member; and a print assembly disposed across the substrate support, the print assembly comprising a printhead and a calibration imaging device positionable to face the stage member.

Abstract: Provided herein are methods and compositions for editing the genome of a cell. In some embodiments, a nucleotide sequence of at least 200 nucleotides in length is inserted into a target region in the genome of a cell.

Abstract: A method of fabricating a visible spectrum optical component includes: providing a substrate; forming a resist layer over a surface of the substrate; patterning the resist layer to form a patterned resist layer defining openings exposing portions of the surface of the substrate; performing deposition to form a dielectric film over the patterned resist layer and over the exposed portions of the surface of the substrate, wherein a top surface of the dielectric film is above a top surface of the patterned resist layer; removing a top portion of the dielectric film to expose the top surface of the patterned resist layer and top surfaces of dielectric units within the openings of the patterned resist layer; and removing the patterned resist layer to retain the dielectric units over the substrate.

Abstract: Ultrasound imaging is a non-invasive, non-radioactive, and low cost technology for diagnosis and identification of implantable medical devices in real time. Developing new ultrasound activated coatings is important to broaden the utility of in vivo marking by ultrasound imaging. Ultrasound responsive macro-phase segregated micro-composite thin films were developed to be coated on medical devices composed of multiple materials and with multiple shapes and varying surface area. The macro-phase segregated in films having silica micro-shells in polycyanoacrylate produces strong color Doppler signals with the use of a standard clinical ultrasound transducer. Electron microscopy showed a macro-phase separation during slow curing of the cyanoacrylate adhesive, as air-filled silica micro-shells were driven to the surface of the film. The air sealed in the hollow space of the silica shells acted as an ultrasound contrast agent and echo decorrelation of air exposed to ultrasound waves produces color Doppler signals.

Abstract: Apparatuses and processes may be utilized for mixing used polyester into a polyester melt. In some processes an intermediate product stream is branched off from an intermediate stage in a virgin polyester production process. The intermediate product stream is then mixed with recycled polyester flakes in a dynamic mixer, where not more than 60% of a melting energy required to melt all the recycled polyester flakes is generated and/or supplied in the dynamic mixer. The mixture produced in this way is fed into a subsequent stage downstream of the intermediate stage and converted up to the desired degree of polycondensation. In this way, it is possible to physically reutilize used polyester or polyester waste.

Abstract: Provided is a gas fill fixture for use in lyophilization, a related system and method. The gas fill fixture includes a chassis, fill indicator and a lid, such that the chassis and lid together form a cavity for receiving a flexible lyophilization container. The system includes a lyophilization container, a lyophilizer and a gas fill fixture incorporating a chassis, a fill indicator and a lid. The method includes process steps for using the system to lyophilize a fluid.

Abstract: The present disclosure relates to a multipurpose casing device (MCD) which controls fluid flow in a filter casing for the primary purpose of directing contaminated fluid (e.g., groundwater) to contact treatment media inside a fluid-treatment cartridge by sealing off an annular space between the filter casing and the cartridge. The MCD assembly also permits hydraulic testing of the integrity of a barrier wall attached to a filter casing by sealing off an inlet or an outlet screen of a filter casing. The MCD assembly allows measurements of physical or chemical properties of a fluid at a specific elevation in a filter casing using hollow core tools connected to an MCD. The MCD can further be used to surge fluids through inlet and/or outlet screens of filter casing that may need to be periodically cleaned.

Abstract: Crystallographic information of crystalline sample can be determined from one or more three-dimensional diffraction pattern datasets generated based on diffraction patterns collected from multiple crystals. The crystals for diffraction pattern acquisition may be selected based on a sample image. At a location of each selected crystal, multiple diffraction patterns of the crystal are acquired at different angles of incidence by tilting the electron beam, wherein the sample is not rotated while the electron beam is directed at the selected crystal.