Patents by Inventor Alexander R. Abbas

Alexander R. Abbas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR TREATMENT OF MICROBIAL DISORDERS
    Publication number: 20210338778
    Abstract: The present invention relates to compositions and methods for treatment of microbial disorder by modulation of the host immune response. More particularly, the present invention relates to compositions that mediate an anti-microbial immune response, and methods of treating a microbial infection using such compositions.
    Type: Application
    Filed: January 29, 2021
    Publication date: November 4, 2021
    Inventors: Alexander R. ABBAS, Nico P. GHILARDI, Zora MODRUSAN, Dimitry M. DANILENKO, Frederic J. DE SAUVAGE, Wenjun OUYANG, Patricia A. VALDEZ, Yan ZHENG
  • METHODS OF DIAGNOSING AND TREATING EOSINOPHILIC DISORDERS
    Publication number: 20200165679
    Abstract: Methods of diagnosing and treating disorders related to excess eosinophil numbers or activity, including but not limited to asthma, are provided. Also provided are methods of selecting or identifying patients for treatment with certain therapeutic agents that are TH2 pathway inhibitors.
    Type: Application
    Filed: November 1, 2019
    Publication date: May 28, 2020
    Applicant: Genentech, Inc.
    Inventors: ALEXANDER R. ABBAS, JOSEPH R. ARRON, DAVID F. CHOY, GUIQUAN JIA, NICHOLAS J.I. LEWIN-KOH, KATRINA B. MORSHEAD
  • METHODS OF PROGNOSING, DIAGNOSING AND TREATING IDIOPATHIC PULMONARY FIBROSIS
    Publication number: 20190062836
    Abstract: Compositions, kits and methods for assessing the prognosis of idiopathic pulmonary fibrosis in patients are provided. In addition, compositions, kits and methods for diagnosing subtypes of idiopathic pulmonary fibrosis are provided. Also provided are methods for treating idiopathic pulmonary fibrosis.
    Type: Application
    Filed: March 16, 2018
    Publication date: February 28, 2019
    Inventors: Alexander R. ABBAS, Joseph R. ARRON, Sanjay CHANDRIANI, Guiquan JIA, Nicholas J.I. LEWIN-KOH, Daryle DEPIANTO
  • METHODS OF DIAGNOSING AND TREATING EOSINOPHILIC DISORDERS
    Publication number: 20190024178
    Abstract: Methods of diagnosing and treating disorders related to excess eosinophil numbers or activity, including but not limited to asthma, are provided. Also provided are methods of selecting or identifying patients for treatment with certain therapeutic agents that are TH2 pathway inhibitors.
    Type: Application
    Filed: October 9, 2018
    Publication date: January 24, 2019
    Applicant: Genentech, Inc.
    Inventors: ALEXANDER R. ABBAS, JOSEPH R. ARRON, DAVID F. CHOY, GUIQUAN JIA, NICHOLAS J.I. LEWIN-KOH, KATRINA B. MORSHEAD
  • METHODS OF DIAGNOSING AND TREATING EOSINOPHILIC DISORDERS
    Publication number: 20170067108
    Abstract: Methods of diagnosing and treating disorders related to excess eosinophil numbers or activity, including but not limited to asthma, are provided. Also provided are methods of selecting or identifying patients for treatment with certain therapeutic agents that are TH2 pathway inhibitors.
    Type: Application
    Filed: April 22, 2016
    Publication date: March 9, 2017
    Applicant: Genentech, Inc.
    Inventors: ALEXANDER R. ABBAS, JOSEPH R. ARRON, DAVID F. CHOY, GUIQUAN JIA, NICHOLAS J.I. LEWIN-KOH, KATRINA B. MORSHEAD
  • METHODS OF PROGNOSING, DIAGNOSING AND TREATING IDIOPATHIC PULMONARY FIBROSIS
    Publication number: 20160230226
    Abstract: Compositions, kits and methods for assessing the prognosis of idiopathic pulmonary fibrosis in patients are provided. In addition, compositions, kits and methods for diagnosing subtypes of idiopathic pulmonary fibrosis are provided. Also provided are methods for treating idiopathic pulmonary fibrosis.
    Type: Application
    Filed: September 23, 2014
    Publication date: August 11, 2016
    Applicant: GENENTECH, INC.
    Inventors: Alexander R. Abbas, Joseph R. Arron, Sanjay Chandriani, Guiquan Jia, Nicholas J.I. Lewin-Koh, Daryle DePianto
  • GENE EXPRESSION MARKERS FOR INFLAMMATORY BOWEL DISEASE
    Publication number: 20140179620
    Abstract: The present invention relates to methods of gene expression profiling for inflammatory bowel disease pathogenesis, in which the differential expression in a test sample from a mammalian subject of one or more IBD markers relative to a control is determined, wherein the differential expression in the test sample is indicative of an IBD in the mammalian subject from which the test sample was obtained.
    Type: Application
    Filed: August 12, 2013
    Publication date: June 26, 2014
    Applicant: GENENTECH, INC.
    Inventors: Alexander R. Abbas, Hilary Clark, Lauri Diehl, Charles Lees, Colin L. Noble, Jack Satsangi
  • GENE EXPRESSION MARKERS FOR CROHN'S DISEASE
    Publication number: 20140154275
    Abstract: The present invention relates to methods of gene expression profiling for inflammatory bowel disease pathogenesis, in which the differential expression in a test sample from a mammalian subject of one or more IBD markers relative to a control is determined, wherein the differential expression in the test sample is indicative of an IBD in the mammalian subject from which the test sample was obtained.
    Type: Application
    Filed: September 6, 2013
    Publication date: June 5, 2014
    Applicant: GENENTECH, INC.
    Inventors: Alexander R. Abbas, Hilary Clark, Lauri Diehl, Charles Lees, Colin L. Noble, Jack Satsangi
  • METHODS FOR TREATMENT OF MICROBIAL DISORDERS
    Publication number: 20130052159
    Abstract: The present invention relates to compositions and methods for treatment of microbial disorder by modulation of the host immune response. More particularly, the present invention relates to compositions that mediate an anti-microbial immune response, and methods of treating a microbial infection using such compositions.
    Type: Application
    Filed: August 3, 2012
    Publication date: February 28, 2013
    Inventors: Alexander R. Abbas, Nico P. Ghilardi, Zora Modrusan, Dimitry M. Danilenko, Frederic J. De Sauvage, Wenjun Ouyang, Patricia A. Valdez, Yan Zheng
  • METHODS FOR TREATMENT OF MICROBIAL DISORDERS
    Publication number: 20110280828
    Abstract: The present invention relates to compositions and methods for treatment of microbial disorder by modulation of the host immune response. More particularly, the present invention relates to compositions that mediate an anti-microbial immune response, and methods of treating a microbial infection using such compositions.
    Type: Application
    Filed: May 20, 2011
    Publication date: November 17, 2011
    Inventors: Alexander R. ABBAS, Nico P. Ghilardi, Zora Modrusan, Dimitry M. Danilenko, Frederic J. De Sauvage, Wenjun Ouyang, Patricia A. Valdez, Yan Zheng
  • GENE EXPRESSION MARKERS FOR CROHN'S DISEASE
    Publication number: 20110033486
    Abstract: The present invention relates to methods of gene expression profiling for inflammatory bowel disease pathogenesis, in which the differential expression in a test sample from a mammalian subject of one or more IBD markers relative to a control is determined, wherein the differential expression in the test sample is indicative of an IBD in the mammalian subject from which the test sample was obtained.
    Type: Application
    Filed: July 19, 2010
    Publication date: February 10, 2011
    Inventors: Alexander R. ABBAS, Hilary Clark, Lauri Diehl, Charles Lees, Colin L. Noble, Jack Satsangi
  • GENE EXPRESSION MARKERS FOR INFLAMMATORY BOWEL DISEASE
    Publication number: 20100004213
    Abstract: The present invention relates to methods of gene expression profiling for inflammatory bowel disease pathogenesis, in which the differential expression in a test sample from a mammalian subject of one or more IBD markers relative to a control is determined, wherein the differential expression in the lest sample is indicative of an IBD in the mammalian subject from which the lest sample was obtained.
    Type: Application
    Filed: November 26, 2008
    Publication date: January 7, 2010
    Inventors: Alexander R. Abbas, Hilary Clark, Lauri Diehl, Charles Lees, Colin L. Noble, Jack Satsangi
  • Compositions and methods for treatment of microbial disorders
    Publication number: 20090202475
    Abstract: The present invention relates to compositions and methods for treatment of microbial disorder by modulation of the host immune response. More particularly, the present invention relates to compositions that mediate an anti-microbial immune response, and methods of treating a microbial infection using such compositions.
    Type: Application
    Filed: November 7, 2008
    Publication date: August 13, 2009
    Applicant: Genentech, Inc.
    Inventors: Alexander R. Abbas, Nico P. Ghilardi, Zora Modrusan, Dimitry M. Danilenko, Frederic J. De Sauvage, Wenjun Ouyang, Patricia A. Valdez, Yan Zheng
  • GENE EXPRESSION MARKERS FOR INFLAMMATORY BOWEL DISEASE
    Publication number: 20090155788
    Abstract: The present invention provides for a method of detecting the presence of inflammatory bowel disease in gastrointestinal tissues or cells of a mammal by detecting decreased expression of Indian Hedgehog (Ihh) and/or increased expression of Defensin A5 (DefA5) and/or Defensin A6 (DefA6) in the tissues or cells of the mammal relative to a control.
    Type: Application
    Filed: May 22, 2008
    Publication date: June 18, 2009
    Inventors: Alexander R. Abbas, Lauri Diehl, Charles Lees, Colin L. Noble, Jack Satsangi