Abstract: A system for training a quantized neural network dataset, comprising at least one hardware processor adapted to: receive input data comprising a plurality of training input value sets and a plurality of target value sets; in each of a plurality of training iterations: for each layer, comprising a plurality of weight values, of one or more of a plurality of layers of a neural network: compute a set of transformed values by applying to a plurality of layer values one or more emulated non-uniformly quantized transformations by adding to each of the plurality of layer values one or more uniformly distributed random noise values; and compute a plurality of output values; compute a plurality of training output values; and update one or more of the plurality of weight values to decrease a value of a loss function; and output the updated plurality of weight values of the plurality of layers.

Abstract: Provided herein are anti-CCR8 antibodies or antigen binding fragment thereof, which bind to CCR8, wherein the CCR8 is a human CCR8 and the antibody does not bind human CCR4. The anti-CCR8 antibodies or antigen binding fragment of the disclosure are useful for the treatment of cancer diseases through the elimination of regulatory T cells. Also provided herein are methods of use for the anti-CCR8 antibodies or antigen binding fragment thereof.

Abstract: Provided herein are anti-EGFRvII antibodies and binding fragments thereof. The anti-EGFRvIII antibodies of the disclosure are useful for the treatment of cancers through, e.g., antibody-dependent cell cytotoxicity (ADCC). Also provided herein are methods of making and using the anti-EGFRvIII antibodies for the treatment of cancer, and polynucleotides that encode the same.

Abstract: A method of forming a circuit board assembly includes receiving a flat no-lead package. The package includes: a housing having a first side and second side; a circuit disposed within the housing; and an exposed thermal belly pad that is thermally coupled to the circuit and passes at least partially through the first side such that it can be exposed to an environment outside of the housing. The method also includes attaching the second side of the flat no-lead package to a first side of a printed circuit board (PCB) such that the exposed thermal belly pad is opposite the first side of the PCB.

Abstract: An automatic vertical farming system may include a frame defining at least one growth area and configured to support a plurality of vertical plant growth structures within the at least one growth area. The system may include at least one light, at least one liquid conduit, and at least one gas conduit. The system may include at least one robot disposed on a top side of the frame and movably supported by the frame. The at least one robot may include at least one tool configured to manipulate the plurality of vertical plant growth structures. The system may include a control system including at least one processor configured to automatically control illumination by the at least one light, liquid flow through the at least one liquid conduit, gas flow through the at least one gas conduit, and operation of the at least one robot.

Abstract: An automatic vertical farming system may include a frame defining at least one growth area and configured to support a plurality of vertical plant growth structures within the at least one growth area. The system may include at least one light, at least one liquid conduit, and at least one gas conduit. The system may include at least one robot disposed on a top side of the frame and movably supported by the frame. The at least one robot may include at least one tool configured to manipulate the plurality of vertical plant growth structures. The system may include a control system including at least one processor configured to automatically control illumination by the at least one light, liquid flow through the at least one liquid conduit, gas flow through the at least one gas conduit, and operation of the at least one robot.

Abstract: Various methods, systems, and devices for treating tissue ablation are disclosed. Some embodiments disclosed herein pertain to methods of treating tumors, systems used for irradiating tissue and tumors with electromagnetic radiation, components and devices of that system, and kits for providing systems used for irradiating tissue and tumors with electromagnetic radiation. In some embodiments, the system provides sub-ablative infrared radiation that is absorbed by nanoparticles. In some embodiments, the nanoparticles absorb the radiation converting it into heat energy. In some embodiments, though the infrared radiation itself may be sub-ablative, the heat energy generated by the nanoparticles is sufficient to cause thermal coagulation, hyperthermia, and/or tissue ablation.

Abstract: A musical instrument special effects device, comprising a special effects unit connected by wire between the musical instrument and an output device, where the unit is operatively arranged to selectively produce at least one of a plurality of preprogrammed special audio effects; and a controller is operatively arranged to wirelessly control the special effects unit.

Abstract: Various methods, systems, and devices for treating tissue ablation are disclosed. Some embodiments disclosed herein pertain to methods of treating tumors, systems used for irradiating tissue and tumors with electromagnetic radiation, components and devices of that system, and kits for providing systems used for irradiating tissue and tumors with electromagnetic radiation. In some embodiments, the system provides sub-ablative infrared radiation that is absorbed by nanoparticles. In some embodiments, the nanoparticles absorb the radiation converting it into heat energy. In some embodiments, though the infrared radiation itself may be sub-ablative, the heat energy generated by the nanoparticles is sufficient to cause thermal coagulation, hyperthermia, and/or tissue ablation.

Abstract: A musical instrument special effects device, comprising a special effects unit connected by wire between the musical instrument and an output device, where the unit is operatively arranged to selectively produce at least one of a plurality of preprogrammed special audio effects; and a controller is operatively arranged to wirelessly control the special effects unit.

Abstract: Various methods, systems, and devices for treating tissue ablation are disclosed. Some embodiments disclosed herein pertain to methods of treating tumors, systems used for irradiating tissue and tumors with electromagnetic radiation, components and devices of that system, and kits for providing systems used for irradiating tissue and tumors with electromagnetic radiation. In some embodiments, the system provides sub-ablative infrared radiation that is absorbed by nanoparticles. In some embodiments, the nanoparticles absorb the radiation converting it into heat energy. In some embodiments, though the infrared radiation itself may be sub-ablative, the heat energy generated by the nanoparticles is sufficient to cause thermal coagulation, hyperthermia, and/or tissue ablation.

Abstract: Various methods, systems, and devices for treating tissue ablation are disclosed. Some embodiments disclosed herein pertain to methods of treating tumors, systems used for irradiating tissue and tumors with electromagnetic radiation, components and devices of that system, and kits for providing systems used for irradiating tissue and tumors with electromagnetic radiation. In some embodiments, the system provides sub-ablative infrared radiation that is absorbed by nanoparticles. In some embodiments, the nanoparticles absorb the radiation converting it into heat energy. In some embodiments, though the infrared radiation itself may be sub-ablative, the heat energy generated by the nanoparticles is sufficient to cause thermal coagulation, hyperthermia, and/or tissue ablation.

Abstract: Various methods, systems, and devices for treating tissue ablation are disclosed. Some embodiments disclosed herein pertain to methods of treating tumors, systems used for irradiating tissue and tumors with electromagnetic radiation, components and devices of that system, and kits for providing systems used for irradiating tissue and tumors with electromagnetic radiation. In some embodiments, the system provides sub-ablative infrared radiation that is absorbed by nanoparticles. In some embodiments, the nanoparticles absorb the radiation converting it into heat energy. In some embodiments, though the infrared radiation itself may be sub-ablative, the heat energy generated by the nanoparticles is sufficient to cause thermal coagulation, hyperthermia, and/or tissue ablation.

Abstract: An automatic vertical farming system may include a frame defining at least one growth area and configured to support a plurality of vertical plant growth structures within the at least one growth area. The system may include at least one light, at least one liquid conduit, and at least one gas conduit. The system may include at least one robot disposed on a top side of the frame and movably supported by the frame. The at least one robot may include at least one tool configured to manipulate the plurality of vertical plant growth structures. The system may include a control system including at least one processor configured to automatically control illumination by the at least one light, liquid flow through the at least one liquid conduit, gas flow through the at least one gas conduit, and operation of the at least one robot.

Abstract: Methods are provided for the treatment of diseases and disorders using systematically-introduced nanoparticles to create a focused localized hyperthermia in a target area to enhance the effect of additional treatment therapies such as ionizing radiation. Advantages include an enhancement of the therapeutic effect of other therapies by increasing perfusion or reducing hypoxia in the treatment area, further, the methods herein may also result in the disruption of the vasculature, which provide further impetus for such treatments, singly and in combination with conventional therapies such as chemotherapy and radiation therapy.

Abstract: Device to be attached to a wounded person for recording and reporting medical and logistic information relating to the wounded person in mass casualty event is disclosed, the device is battery free and comprises (i) a solid state memory; (ii) a plurality of actuators in a predetermined correlation with a graphical presentation presented on external surface of the device such that a status of each actuator represents a medical or logistic information relating to the wounded person; (iii) a conversion adapter configured to translate a status of the actuators into respective digital codes or to transfer the status of the actuators to external real time translator for returning the status in the form of respective digital codes wherein said codes represent medical or logistic information relating to the wounded person and are respectively loaded into the solid state memory by the conversion adapter or by the external translator; and (iv) an interface configured to communicate with a mobile electrically powered co

Abstract: Methods are provided for the treatment of diseases and disorders using systematically-introduced nanoparticles to create a focused localized hyperthermia in a target area to enhance the effect of additional treatment therapies such as ionizing radiation. Advantages include an enhancement of the therapeutic effect of other therapies by increasing perfusion or reducing hypoxia in the treatment area, further, the methods herein may also result in the disruption of the vasculature, which provide further impetus for such treatments, singly and in combination with conventional therapies such as chemotherapy and radiation therapy.

Abstract: Methods are provided for the treatment of diseases and disorders using systematically-introduced nanoparticles to create a focused localized hyperthermia in a target area to enhance the effect of additional treatment therapies such as ionizing radiation. Advantages include an enhancement of the therapeutic effect of other therapies by increasing perfusion or reducing hypoxia in the treatment area, further, the methods herein may also result in the disruption of the vasculature, which provide further impetus for such treatments, singly and in combination with conventional therapies such as chemotherapy and radiation therapy.

Abstract: An abrasive member comprises a metal film (2) attached to one surface of a flexible sheet (1), a mask (13) of plating resistant material on the exposed surface of the metal film, the plating resistant material having a multitude of discrete openings (14) therein, and metal (3) electrodeposited through the discrete openings onto the metal film in the presence of particulate abrasive material so that the material adheres directly to the metal film and the abrasive (4) is embedded in the metal deposits.

Abstract: A method of forming an abrasive member comprises fixedly attaching a metal film to one surface of a flexible sheet, applying a mask of plating resistant material to the exposed surface of the metal film, said plating resistant material having a multitude of discrete openings therein, and electrodepositing metal through said discrete openings onto said metal film in the presence of particulate abrasive material so that the material adheres directly to said metal film and the abrasive becomes embedded in the metal desposits.