Abstract: The invention relates to a new method for obtaining aptamers directed against protein targets comprising a histidine-containing surface domain, and aptamers obtaining by said method.

Abstract: A method for preparing a dried powder is provided. The facility includes a first drying chamber having a heating element and a second drying chamber. A mixture of powder and diluent is introduced into the first drying chamber. A pre-dried powder is transferred from the first drying chamber into the second drying chamber. A dried powder, including a recirculated amount of powder and a discharge amount of powder, is formed in the second drying chamber. The recirculated amount of the dried powder is transferred by a conveyor device from the second drying chamber into the first drying chamber. The discharge amount of the dried powder is discharged from the second drying chamber.

Abstract: A method for preparing a dried powder is provided. The facility includes a first drying chamber having a heating element and a second drying chamber. A mixture of powder and diluent is introduced into the first drying chamber. A pre-dried powder is transferred from the first drying chamber into the second drying chamber. A dried powder, including a recirculated amount of powder and a discharge amount of powder, is formed in the second drying chamber. The recirculated amount of the dried powder is transferred by a conveyor device from the second drying chamber into the first drying chamber. The discharge amount of the dried powder is discharged from the second drying chamber.

Abstract: The invention relates to aptamers which specifically bind to fibrinogen and their use in the purification of said protein.

Abstract: The invention relates to a new method for obtaining aptamers directed against protein targets comprising a histidine-containing surface domain, and aptamers obtaining by said method.

Abstract: The invention relates to aptamers which specifically bind to immunoglobulin G and their use in the purification of said protein.

Abstract: A filter housing has first and second housing parts connected to each other to be openable and secured by a latching element. The latching element is connected to the first housing part by a moveable connection with a predetermined breaking point and is pivotable by the movable connection into the closed state. The latching element has two positioning elements and the housing parts have counter positioning elements. In the closed state, the counter positioning elements are axially arranged between the two positioning elements and the positioning elements form a stop for the counter positioning elements. The latching element has an element locking section locking at a housing locking section on the first or second housing part. The predetermined breaking point is subjected to mechanical stress such that the predetermined breaking point breaks upon locking or release of the latching element.

Abstract: A deflectable tip videoarthroscope of 5.4 mm diameter or smaller, comprising a miniaturized chip-in-tip CCD with four-way angulations mounted on the distal end of the arthroscope. The deflectable tip videoarthroscope may be provided with a replaceable distal window made of a thin material (such as polycarbonate or acrylic) or a glass (sapphire or other) with very high light transmission properties, connected to a sheathing system that is disposable or limited-reusable, which could be discarded if a shaver burr or ablation probe contacts the lens. This design protects the distal window of the videoarthroscope during use and reduces scope repair costs and system down-time. The deflectable tip videoarthroscope may additionally include a steering wheel, which allows 360 degree rotation of the instrument during arthroscopic procedures. The videoarthroscope may further include an irrigation channel or a wireless imager control system.

Abstract: A filter housing has first and second housing parts connected to each other to be openable and secured by a latching element. The latching element is connected to the first housing part by a moveable connection with a predetermined breaking point and is pivotable by the movable connection into the closed state. The latching element has two positioning elements and the housing parts have counter positioning elements. In the closed state, the counter positioning elements are axially arranged between the two positioning elements and the positioning elements form a stop for the counter positioning elements. The latching element has an element locking section locking at a housing locking section on the first or second housing part. The predetermined breaking point is subjected to mechanical stress such that the predetermined breaking point breaks upon locking or release of the latching element.

Abstract: A deflectable tip videoarthroscope of 5.4 mm diameter or smaller, comprising a miniaturized chip-in-tip CCD with four-way angulations mounted on the distal end of the arthroscope. The deflectable tip videoarthroscope may be provided with a replaceable distal window made of a thin material (such as polycarbonate or acrylic) or a glass (sapphire or other) with very high light transmission properties, connected to a sheathing system that is disposable or limited-reusable, which could be discarded if a shaver burr or ablation probe contacts the lens. This design protects the distal window of the videoarthroscope during use and reduces scope repair costs and system down-time. The deflectable tip videoarthroscope may additionally include a steering wheel, which allows 360 degree rotation of the instrument during arthroscopic procedures. The videoarthroscope may further include an irrigation channel or a wireless imager control system.