Patents by Inventor Alexander Senderikhin

Alexander Senderikhin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Derivatives of branch-chain lipophilic molecular and uses thereof
    Patent number: 7687483
    Abstract: Novel phospho-derivatives of branched-chain lipophilic molecules useful for permeabilizing biological barriers and for inhibiting tumor growth are disclosed. Pharmaceutical compositions comprising phospho-derivatives of branched-chain lipophilic molecules and their uses are also disclosed.
    Type: Grant
    Filed: January 11, 2007
    Date of Patent: March 30, 2010
    Assignee: D-Pharm Ltd.
    Inventors: Alexander Kozak, Marina Vinnikova, Michael Polyak, Eliezer Beit-Yannai, Dalia Reznitsky-Cohen, Alexander Senderikhin
  • Derivatives of branch-chain lipophilic molecular and uses thereof
    Publication number: 20070135381
    Abstract: Novel phospho-derivatives of branched-chain lipophilic molecules useful for permeabilizing biological barriers and for inhibiting tumor growth are disclosed. Pharmaceutical compositions comprising said molecules and their uses are also disclosed.
    Type: Application
    Filed: January 11, 2007
    Publication date: June 14, 2007
    Applicant: D-PHARM LTD.
    Inventors: Alexander Kozak, Marina Vinnikova, Michael Polyak, Eliezer Beit-Yannai, Dalia Reznisky-Cohen, Alexander Senderikhin
  • Derivatives of branched-chain lipophilic molecules and uses thereof
    Patent number: 7186703
    Abstract: The present invention discloses novel phospho-derivatives of branched-chain lipophilic molecules useful for permeabilizing biological barriers and for inhibiting tumor growth. The invention further discloses pharmaceutical compositions comprising said molecules and their uses.
    Type: Grant
    Filed: August 1, 2001
    Date of Patent: March 6, 2007
    Assignee: D-Pharm Ltd.
    Inventors: Alexander Kozak, Marina Vinnikova, Michael Polyak, Eliezer Beit-Yannai, Dalia Reznitsky-Cohen, Alexander Senderikhin
  • Phospholipid prodrugs of anti-proliferative drugs
    Patent number: 6774121
    Abstract: The invention discloses prodrugs comprising anti-proliferative drugs covalently linked, via bridging group, to a phospholipid moiety such that the active species is preferentially released, preferably by enzymatic cleavage, at the required site of action. The invention further discloses pharmaceutical compositions said prodrugs and the uses thereof for the treatment of diseases and disorders related to inflammatory, to degenerative or atrophic conditions, and to uncontrolled cell growth. FIG. 1 depicts a graph of animal survival during the course of an experiment wherein mice were i.p. transplanted with 11210 mouse leukemia cells and then treated with vehicle only (squares), MTX (triangles) or molar equivalent dose of DP-MTX071 (circles) according to the regiment described example in Example 11.
    Type: Grant
    Filed: March 13, 2002
    Date of Patent: August 10, 2004
    Assignee: D-Pharm, Ltd.
    Inventors: Alexander Kozak, Israel Shapiro, Marina Vinnikova, Leonid Ershov, Alexander Senderikhin, Oran Ayalon
  • Derivatives of branched-chain lipophilic molecules and uses thereof
    Publication number: 20030186897
    Abstract: The present invention discloses novel phospho-derivatives of branched-chain lipophilic molecules useful for permeabilizing biological barriers and for inhibiting tumor growth. The invention further discloses pharmaceutical compositions comprising said molecules and their uses.
    Type: Application
    Filed: January 27, 2003
    Publication date: October 2, 2003
    Inventors: Alexander Kozak, Marina Vinnikova, Michael Polyak, Eliezer Beit-Yannai, Dalia Reznitsky-Cohen, Alexander Senderikhin