Abstract: The invention relates to a device for simulating a belt slack and/or for simulating belt forces, comprising a guide (12) for a seatbelt (20) which includes static guide elements (14) and a movable deflection element (16) which is adjustable relative to the latter from an initial state via an intermediate state to a final state, and at least one inertial mass (18), wherein the guideway (17) for a seatbelt (20) predetermined by the deflection element (16) and the adjacent guide elements (14) is V-shaped in the initial state and the deflection element (16) and the inertial mass (18) do not interact, in the intermediate state is designed to be less V-shaped and the deflection element (16) and the inertial mass (18) interact, and the predetermined guideway (17) is at least approximately linear in the final state.

Abstract: The invention relates to a belt retractor (10) for a vehicle seatbelt, comprising a rotatable retractor shaft (14) for a belt reel (16) and bearings (18) disposed at the two axial ends of the retractor shaft (14). One of the bearings (18) has a first cylindrical bearing surface (30) and a second cylindrical bearing surface (32) axially offset against the first bearing surface (30). The bearing (18) is configured so that, when the belt reel (16) is radially loaded, the retractor shaft (14) is supported on the second bearing surface (32) and, in the radially unloaded state of the belt reel (16), the retractor shaft (14) is supported only on the first bearing surface (30).

Abstract: The invention relates to a belt retractor (10) for a vehicle seatbelt, comprising a rotatable retractor shaft (14) for a belt reel (16) and bearings (18) disposed at the two axial ends of the retractor shaft (14). One of the bearings (18) has a first cylindrical bearing surface (30) and a second cylindrical bearing surface (32) axially offset against the first bearing surface (30). The bearing (18) is configured so that, when the belt reel (16) is radially loaded, the retractor shaft (14) is supported on the second bearing surface (32) and, in the radially unloaded state of the belt reel (16), the retractor shaft (14) is supported only on the first bearing surface (30).

Abstract: Method for the detection of the in-vivo activity of neurotrypsin wherein the amount of the 22-kDa-fragment of agrin is measured in a sample taken from a patient and the measured amount of the 22-kDa-fragment of agrin in the sample is used to calculate the activity of neurotrypsin, use of the method for diagnosis and monitoring of neurotrypsin-related disturbances and use of the 22-kDa-fragment of agrin as biomarker for neurotrypsin-related disturbances.