Patents by Inventor Alexander Straub

Alexander Straub has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted 2-oxo-3-phenyl-5-carbonylaminomethyl-1,3-oxazolines and their use as anticoagulant and antithrombotics
    Patent number: 7582666
    Abstract: The invention relates to the field of blood coagulation, more particularly, to novel compounds of general formula (I), to a method for producing the compounds and to their use as active ingredients in medicaments for the prevention and/or the treatment of diseases.
    Type: Grant
    Filed: March 31, 2006
    Date of Patent: September 1, 2009
    Assignee: Bayer Schering Pharma AG
    Inventors: Alexander Straub, Thomas Lampe, Josef Pernerstorfer, Elisabeth Perzborn, Jens Pohlmann, Susanne Rohrig, Karl-Heinz Schlemmer
  • Alkyl-Analide Producing Method
    Publication number: 20090209769
    Abstract: The present invention relates to a process for preparing known fungicidally effective alkylanilides from acid chlorides and aminoacetophenone via hydroxyalkyl-substituted carboxanilides, alkenylanilides and benzoxazine derivatives.
    Type: Application
    Filed: March 1, 2006
    Publication date: August 20, 2009
    Applicant: Bayer CropScience AG
    Inventor: Alexander Straub
  • Substituted oxazolidinones and their use in the field of blood coagulation
    Patent number: 7576111
    Abstract: The invention relates to the field of blood coagulation. Novel oxazolidinone derivatives of the general formula (I) processes for their preparation and their use as medicinally active compounds for the prophylaxis and/or treatment of disorders are described.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: August 18, 2009
    Assignee: Bayer Schering Pharma AG
    Inventors: Alexander Straub, Thomas Lampe, Jens Pohlmann, Susanne Rohrig, Elisabeth Perzborn, Karl-Heinz Schlemmer, Joseph Pernerstorfer
  • Substituted isoindoles and their use
    Patent number: 7482472
    Abstract: The invention relates to coagulation of the blood. Disclosed are novel compounds of formula (I), a method for the production of these compounds, pharmaceutical compositions containing them, and methods of using them for the prevention and/or treatment of various diseases.
    Type: Grant
    Filed: March 12, 2007
    Date of Patent: January 27, 2009
    Assignee: Bayer Healthcare AG
    Inventors: Alexander Straub, Thomas Lampe, Jens Pohlmann, Susanne Rohrig, Elisabeth Perzborn, Karl-Heinz Schlemmer
  • Method for producing halogenated 2-(3-butenylsulphanyl)-1,3-thiazoles
    Patent number: 7439408
    Abstract: The present invention relates to a process for preparing a compound of formula (V) where R is H or F, by reacting a compound of formula (IV) where R is H or F, with hydrogen sulphide or salts thereof, optionally in the presence of a reaction auxiliary and optionally in the presence of a diluent.
    Type: Grant
    Filed: April 13, 2006
    Date of Patent: October 21, 2008
    Assignee: Bayer Cropscience AG
    Inventor: Alexander Straub
  • REINFORCING COMPONENT
    Publication number: 20080217960
    Abstract: A lengthwise extended component contains of a support that possesses flow channels in the direction of its longitudinal axis. The support additionally possesses external surfaces that are offset to each other in the direction of the longitudinal axis as well as a lateral external surface. These external surfaces are provided with a layer of a thermally expansible and curable composition. Reinforcing components of this type are suitable for stiffening and/or reinforcing hollow supports, such as the A-, B- or C-pillars, the roof edges or the rocker panels of vehicles, especially passenger cars.
    Type: Application
    Filed: December 5, 2007
    Publication date: September 11, 2008
    Inventors: Stefan Kochert, Jochen Becker, Ralph Dalhaeuser, Andres Stiller, Alexander Straub, Thomas Hogger, Mark Riess, Josef Reindl, Juergen Kempf, Niklas Eberle, Robert Schalausky
  • SUBSTITUTED OXAZOLIDINONES AND THEIR USE IN THE FIELD OF BLOOD COAGULATION
    Publication number: 20080200674
    Abstract: The invention relates to the field of blood coagulation. Novel oxazolidinone derivatives of the general formula (I) processes for their preparation and their use as medicinally active compounds for the prophylaxis and/or treatment of disorders are described.
    Type: Application
    Filed: February 7, 2008
    Publication date: August 21, 2008
    Applicant: Bayer Healthcare Aktiengesellschaft
    Inventors: Alexander Straub, Thomas Lampe, Jens Pohlmann, Susanne Rohrig, Elisabeth Perzborn, Karl-Heinz Schlemmer, Joseph Pernerstorfer
  • Method for producing halogenated 2-(3-butenylsulphanyl)-1,3-thiazoles
    Patent number: 7385093
    Abstract: The present invention relates to a process for preparing compounds of formula (IV) where R is H or F, by reacting a compound of formula (II) where where R is H or F, and X is bromine, chlorine, mesylate, or tosylate, with a thiocyanate salt of formula (III) M+SCN???(III) where M+ is hydrogen, an ammonium ion, a tetraalkylammonium ion, or an alkali metal or alkaline earth metal ion, optionally in the presence of a reaction auxiliary and optionally in the presence of a diluent.
    Type: Grant
    Filed: April 13, 2006
    Date of Patent: June 10, 2008
    Assignee: Makhteshim Chemical Works Ltd.
    Inventor: Alexander Straub
  • SUBSTITUTED OXAZOLIDINONES AND THEIR USE IN THE FIELD OF BLOOD COAGULATION
    Publication number: 20080090815
    Abstract: The invention relates to the field of blood coagulation. Novel oxazolidinone derivatives of the general formula (I) processes for their preparation and their use as medicinally active compounds for the prophylaxis and/or treatment of disorders are described.
    Type: Application
    Filed: October 31, 2007
    Publication date: April 17, 2008
    Inventors: Alexander Straub, Thomas Lampe, Jens Pohlmann, Susanne Rohrig, Elisabeth Perzborn, Karl-Heinz Schlemmer, Joseph Pernerstorfer
  • Substituted isoindoles and their use
    Publication number: 20080039446
    Abstract: The invention relates to coagulation of the blood. Disclosed are novel compounds of formula (I), a method for the production of these compounds, pharmaceutical compositions containing them, and methods of using them for the prevention and/or treatment of various diseases.
    Type: Application
    Filed: March 12, 2007
    Publication date: February 14, 2008
    Applicant: Bayer HealthCare AG
    Inventors: Alexander Straub, Thomas Lampe, Jens Pohlmann, Susanne Rohrig, Elisabeth Perzborn, Karl-Heinz Schlemmer
  • Methods of treating medical conditions using sulfonate-substituted pyrazolopyridine derivatives
    Patent number: 7317016
    Abstract: This invention relates to methods of treatment of cardiovascular disorders, thromboembolic disorders, inflammation, and disorders of the central nervous system using pyrazol pyridine derivatives of formula (I) wherein R1 is a radical of the formula —O—SO2—R3 in which R3 is optionally substituted C1-6-alkyl, optionally substituted C3-8-cycloalkyl, or optionally substituted phenyl; R2 is H, optionally substituted C1-6-alkyl-CO— or optionally substituted C1-6-alkyl-SO2—; as well as salts, stereoisomers, tautomers, and hydrates thereof.
    Type: Grant
    Filed: July 5, 2005
    Date of Patent: January 8, 2008
    Assignee: Bayer Aktiengesellschaft
    Inventors: Johannes-Peter Stasch, Achim Feurer, Stefan Weigand, Elke Stahl, Dietmar Flubacher, Cristina Alonso-Alija, Frank Wunder, Dieter Lang, Klaus Dembowsky, Alexander Straub, Elisabeth Perzborn
  • Medical uses of carbamate-substituted pyrazolo-pyridine derivatives
    Patent number: 7291622
    Abstract: This invention relates to methods for treating sexual dysfunction, by administering a compound of the formula wherein R1 is H or a di-C1-6-alkylaminocarbonyl radical, and R2 is a radical of the formula —O—C(X)—NR3R4 wherein X is O or S. The compound may also be administered in combination with at least one organic nitrate or NO donor, or in combination with at least one compound which inhibits the breakdown of cyclic guanosine monophosphate (cGMP).
    Type: Grant
    Filed: July 29, 2005
    Date of Patent: November 6, 2007
    Assignee: Bayer Aktiengesellschaft
    Inventors: Johannes-Peter Stasch, Achim Feurer, Stefan Weigand, Elke Stahl, Dietmar Flubacher, Cristina Alonso-Alija, Frank Wunder, Dieter Lang, Klaus Dembowsky, Alexander Straub, Elizabeth Perzborn
  • Method for the production of 4-(4-aminophenyl)-3-morpholinone
    Publication number: 20070066611
    Abstract: The present invention relates to a process for preparing 4-(4-aminophenyl)-3-morpholinone by reacting 4-(4-nitrophenyl)-3-morpholinone with hydrogen in the presence of a hydrogenation catalyst, characterized in that the reaction is effected in an aliphatic alcohol.
    Type: Application
    Filed: September 9, 2004
    Publication date: March 22, 2007
    Applicant: Bayer HealthCare AG
    Inventors: Christian Thomas, Mathias Berwe, Alexander Straub
  • Heterocyclic compounds
    Publication number: 20070066615
    Abstract: The present invention relates to the area of blood clotting. The invention relates in particular to certain heterocyclic compounds, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases.
    Type: Application
    Filed: May 6, 2004
    Publication date: March 22, 2007
    Applicant: BAYER HEATHCARE AG
    Inventors: Christoph Gerdes, Elisabeth Perzborn, Jens Pohlmann, Susanne Rohrig, Alexander Straub, Christian Thomas, Arounarith Tuch, Karl-Heinz Schlemmer
  • Substituted isoindoles and their use thereof
    Patent number: 7189738
    Abstract: The invention relates to coagulation of the blood. Disclosed are novel compounds of formula (I), a method for the production of these compounds, pharmaceutical compositions containing them, and methods of using them for the prevention and/or treatment of various diseases.
    Type: Grant
    Filed: July 17, 2002
    Date of Patent: March 13, 2007
    Assignee: Bayer Healthcare AG
    Inventors: Alexander Straub, Thomas Lampe, Jens Pohlmann, Susanne Rohrig, Elisabeth Perzborn, Karl-Heinz Schlemmer
  • Substituted oxazolidinones and their use in the field of blood coagulation
    Patent number: 7157456
    Abstract: The invention relates to the field of blood coagulation. Novel oxazolidinone derivatives of the general formula (I) processes for their preparation and their use as medicinally active compounds for the prophylaxis and/or treatment of disorders are described.
    Type: Grant
    Filed: December 11, 2000
    Date of Patent: January 2, 2007
    Assignee: Bayer HealthCare AG
    Inventors: Alexander Straub, Thomas Lampe, Jens Pohlmann, Susanne Röhrig, Elisabeth Perzborn, Karl-Heinz Schlemmer, Joseph Pernerstorfer
  • Substituted Oxazolidinones and Their Use in the Field of Blood Coagulation
    Publication number: 20060258724
    Abstract: The invention relates to the field of blood coagulation. Novel oxazolidinone derivatives of the general formula (I) processes for their preparation and their use as medicinally active compounds for the prophylaxis and/or treatment of disorders are described.
    Type: Application
    Filed: July 27, 2006
    Publication date: November 16, 2006
    Inventors: Alexander Straub, Thomas Lampe, Jens Pohlmann, Susanne Rohrig, Elisabeth Perzborn, Karl-Heinz Schlemmer, Joseph Pernerstorfer
  • Sulfonamide-substituted pyrazolopyridine compounds
    Patent number: 7115599
    Abstract: This invention relates to compounds of the formula in which R1, R2, and R3 are as defined in the claims, to a process for preparing such compounds, to pharmaceutical compositions containing such compounds, and to methods of using such compounds for treatment of hypertension and sexual dysfunction.
    Type: Grant
    Filed: November 12, 2001
    Date of Patent: October 3, 2006
    Assignee: Bayer Aktiengesellschaft
    Inventors: Johannes-Peter Stasch, Achim Feurer, Stefan Weigand, Elke Stahl, Dietmar Flubacher, Cristina Alonso-Alija, Frank Wunder, Dieter Lang, Klaus Dembowsky, Alexander Straub, Elisabeth Perzborn
  • Carbamate-substituted pyrazolopyridine-derivatives
    Patent number: 7105523
    Abstract: This invention relates to compounds of the formula wherein R1 is H or a di-C1-6-alkylaminocarbonyl raical, and R2 is a radical of the formula —O—C(X)—NR3R4 wherein X is O or S. A process for preparing such compounds, pharmaceutical compositions containing them, and methods for using them in treatment of hypertension are also disclosed and claimed.
    Type: Grant
    Filed: November 9, 2001
    Date of Patent: September 12, 2006
    Assignee: Bayer Aktiengeselischaft
    Inventors: Johannes-Peter Stasch, Achim Feurer, Stefan Weigand, Elke Stahl, Dietmar Flubacher, Cristina Alonso-Alija, Frank Wunder, Dieter Lang, Klaus Dembowsky, Alexander Straub, Elisabeth Perzborn
  • Method for producing halogenated 2-(3-butenylsulphanyl)-1,3-thiazoles
    Publication number: 20060183914
    Abstract: The present invention relates to a process for preparing compounds of formula (IV) where R is H or F, by reacting a compound of formula (II) where where R is H or F, and X is bromine, chlorine, mesylate, or tosylate, with a thiocyanate salt of formula (III) M+SCN???(III) where M+ is hydrogen, an ammonium ion, a tetraalkylammonium ion, or an alkali metal or alkaline earth metal ion, optionally in the presence of a reaction auxiliary and optionally in the presence of a diluent.
    Type: Application
    Filed: April 13, 2006
    Publication date: August 17, 2006
    Inventor: Alexander Straub