Patents by Inventor Alexander Triebl

Alexander Triebl has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Determining enrichments of tracers of glucose by mass spectrometry
    Patent number: 11454616
    Abstract: Provided is a method for determining, in a sample, enrichments of a first and a second stable-labeled tracer of a target substance including glucose, the first tracer and the second tracer having the same or similar chemical structure as the target substance, the method including: ionizing the first tracer, the second tracer and the target substance of the sample; measuring intensities of ions deriving from the target substance, the first tracer and the second tracer using a mass analyzer; calculating an enrichment of the first tracer from a first ratio of intensity of the ions deriving from the first tracer to the intensity of the ions deriving from the target substance employing a first calibration curve independent of enrichments of each of the second tracer; wherein the mass analyzer is operated so as to resolve an ion peak deriving from a tracer and having a width ?(m/z) at half maximum peak height equal to or smaller than 1×10?2.
    Type: Grant
    Filed: June 22, 2018
    Date of Patent: September 27, 2022
    Assignee: Medizinische Universität Graz
    Inventors: Werner Regittnig, Harald Köfeler, Martin Trötzmüller, Alexander Triebl
  • Determining Enrichments of Tracers of Glucose by Mass Spectrometry
    Publication number: 20200217828
    Abstract: Provided is a method for determining, in a sample, enrichments of a first and a second stable-labeled tracer of a target substance including glucose, the first tracer and the second tracer having the same or similar chemical structure as the target substance, the method including: ionizing the first tracer, the second tracer and the target substance of the sample; measuring intensities of ions deriving from the target substance, the first tracer and the second tracer using a mass analyzer; calculating an enrichment of the first tracer from a first ratio of intensity of the ions deriving from the first tracer to the intensity of the ions deriving from the target substance employing a first calibration curve independent of enrichments of each of the second tracer; wherein the mass analyzer is operated so as to resolve an ion peak deriving from a tracer and having a width ?(m/z) at half maximum peak height equal to or smaller than 1×10?2.
    Type: Application
    Filed: June 22, 2018
    Publication date: July 9, 2020
    Inventors: Werner Regittnig, Harald Köfeler, Martin Trötzmüller, Alexander Triebl