Abstract: A system and method for localizing software having resource references and a resource library. A record of all resource calls performed by the software is generated. New resources are added to the resource library, and instructions are included, that map individual resource calls to resources in the resource library.

Abstract: The invention provides methods for evolving a polynucleotide toward acquisition of a desired property. Such methods entail incubating a population of parental polynucleotide variants under conditions to generate annealed polynucleotides comprising heteroduplexes. The heteroduplexes are then exposed to a cellular DNA repair system to convert the heteroduplexes to parental polynucleotide variants or recombined polynucleotide variants. The resulting polynucleotides are then screened or selected for the desired property.

Abstract: The invention provides methods for evolving a polynucleotide toward acquisition of a desired property. Such methods entail incubating a population of parental polynucleotide variants under conditions to generate annealed polynucleotides comprising heteroduplexes. The heteroduplexes are then exposed to a cellular DNA repair system to convert the heteroduplexes to parental polynucleotide variants or recombined polynucleotide variants. The resulting polynucleotides are then screened or selected for the desired property.

Abstract: The invention relates to a method, a cryosurgical probe, and a cryosurgical instrument for freezing a lesion on biological tissue. The method involves repeated cycles of freezing and thawing of the tissue to ensure maximum treatment effectiveness. The cryosurgical probe may be positioned on an end of a cryosurgical instrument, and facilitates the freezing of a lesion on biological tissue via the evaporation of a refrigerant. The cryosurgical probe includes a receiving end, a hollow portion, and a tissue contact end. The receiving end is adapted to receive the refrigerant. The tissue contact end includes an orifice adapted to expose the lesion to the refrigerant, and preferably includes a guard portion adapted to prevent excessive exposure of the biological tissue surrounding the lesion to the refrigerant. The hollow portion allows the flow of refrigerant from the receiving end to the tissue contact end, and includes at least one exhaust port.

Abstract: Described herein are methods for generating recombined nucleic acids. In one method, fragments of a sequence are provided wherein the fragments have non-extendable 3? ends. A primer is provided and the primer and fragments are reacted under conditions to extend the primer to form a recombined nucleic acid molecule. In the methods herein, the non-extendable fragments act only as templates, rather than as templates and primers.

Abstract: Described herein are methods for generating recombined nucleic acids. In one method, fragments of a sequence are provided wherein the fragments have non-extendable 3? ends. A primer is provided and the primer and fragments are reacted under conditions to extend the primer to form a recombined nucleic acid molecule. In the methods herein, the non-extendable fragments act only as templates, rather than as templates and primers.

Abstract: An adaptive filter is programmed with an algorithm based on a normalized Least Mean Squares (nLMS) algorithm that adapts each sample time. The algorithm is modified to be more efficient in a variety of DSPs by computing multiple errors, one per sample, before updating coefficients. The update equation utilizes the multiple errors to achieve adaptation at a similar performance to known nLMS algorithms that adapt each sample time but without the instability that is observed in low echo-to-near-end-noise ratio (ENR) input conditions. Varying the relaxation step size prevents divergence. The DSP utilizes either one or more MAC units.

Abstract: An adaptive filter is programmed with an algorithm based on a normalized Least Mean Squares (nLMS) algorithm that adapts each sample time. The algorithm is modified to be more efficient in a variety of DSPs by computing multiple errors, one per sample, before updating coefficients. The update equation utilizes the multiple errors to achieve adaptation at a similar performance to known nLMS algorithms that adapt each sample time but without the instability that is observed in low echo-to-near-end-noise ratio (ENR) input conditions. Varying the relaxation step size prevents divergence. The DSP utilizes either one or more MAC units.

Abstract: The invention provides methods for evolving a polynucleotide toward acquisition of a desired property. Such methods entail incubating a population of parental polynucleotide variants under conditions to generate annealed polynucleotides comprising heteroduplexes. The heteroduplexes are then exposed to a cellular DNA repair system to convert the heteroduplexes to parental polynucleotide variants or recombined polynucleotide variants. The resulting polynucleotides are then screened or selected for the desired property.

Abstract: Described herein are methods for generating recombined nucleic acids. In one method, fragments of a sequence are provided wherein the fragments have non-extendable 3′ ends. A primer is provided and the primer and fragments are reacted under conditions to extend the primer to form a recombined nucleic acid molecule. In the methods herein, the non-extendable fragments act only as templates, rather than as templates and primers.

Abstract: The invention provides methods for evolving a polynucleotide toward acquisition of a desired property. Such methods entail incubating a population of parental polynucleotide variants under conditions to generate annealed polynucleotides comprising heteroduplexes. The heteroduplexes are then exposed to a cellular DNA repair system to convert the heteroduplexes to parental polynucleotide variants or recombined polynucleotide variants. The resulting polynucleotides are then screened or selected for the desired property.

Abstract: Described herein are methods for generating recombined nucleic acids. In one method, fragments of a sequence are provided wherein the fragments have non-extendable 3′ ends. A primer is provided and the primer and fragments are reacted under conditions to extend the primer to form a recombined nucleic acid molecule. In the methods herein, the non-extendable fragments act only as templates, rather than as templates and primers.