Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for determining a predicted structure of a protein that is specified by an amino acid sequence. In one aspect, a method comprises: obtaining a multiple sequence alignment for the protein; determining, from the multiple sequence alignment and for each pair of amino acids in the amino acid sequence of the protein, a respective initial embedding of the pair of amino acids; processing the initial embeddings of the pairs of amino acids using a pair embedding neural network comprising a plurality of self-attention neural network layers to generate a final embedding of each pair of amino acids; and determining the predicted structure of the protein based on the final embedding of each pair of amino acids.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for determining a predicted structure of a protein that is specified by an amino acid sequence. In one aspect, a method comprises: obtaining a multiple sequence alignment for the protein; determining, from the multiple sequence alignment and for each pair of amino acids in the amino acid sequence of the protein, a respective initial embedding of the pair of amino acids; processing the initial embeddings of the pairs of amino acids using a pair embedding neural network comprising a plurality of self-attention neural network layers to generate a final embedding of each pair of amino acids; and determining the predicted structure of the protein based on the final embedding of each pair of amino acids.

Abstract: A system and a method remotely monitors electrical and/or mechanical equipment where a user may interactively alter the operation of a piece of equipment remotely. As the operation of a device may be altered remotely, a corresponding resource-consumption amount may also be remotely controlled and adjusted. An embodiment of the present inventions is directed to remotely adjusting, or causing the remote adjustment, of the use, state, parameters or characteristics of a device, process or both, for reducing resource demand and/or adding to the resource supply. The remote adjustment may originate from a user associated with the devices, a supplier of a resource for operation of the devices, a utility industry participant, a third party, government entity, a trader or any other entity. The adjustment of resource-consumption may be based on a triggered event/condition, a predetermined schedule or other defined scheme.