Patents by Inventor Alexander Wlodawer

Alexander Wlodawer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Monomeric griffithsin tandemers
    Patent number: 9982025
    Abstract: The invention provides a construct containing two or more monomeric griffithsin molecules, optionally joined by a linker, as well as conjugate comprising the construct, a nucleic acid encoding the construct or conjugate, vectors, and cells. A nucleic acid encoding the polypeptide or fusion protein, as well as compositions or cells comprising the polypeptide, fusion protein, or nucleic acid also are provided.
    Type: Grant
    Filed: June 5, 2014
    Date of Patent: May 29, 2018
    Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Barry R. O'Keefe, Alexander Wlodawer, Tinoush Moulaei
  • MONOMERIC GRIFFITHSIN TANDEMERS
    Publication number: 20160108097
    Abstract: The invention provides a construct containing two or more monomeric griffithsin molecules, optionally joined by a linker, as well as conjugate comprising the construct, a nucleic acid encoding the construct or conjugate, vectors, and cells. A nucleic acid encoding the polypeptide or fusion protein, as well as compositions or cells comprising the polypeptide, fusion protein, or nucleic acid also are provided.
    Type: Application
    Filed: June 5, 2014
    Publication date: April 21, 2016
    Applicant: The United States of America, as represented by the Secretary, Department of Health and Human Serv
    Inventors: Barry R. O'Keefe, Alexander Wlodawer, Tinoush Moulaei
  • Recombinant ribonuclease proteins
    Patent number: 6045793
    Abstract: The invention relates to ribonucleases derived from a native ribonuclease found in the oocytes of Rana pipiens. Various humanized and recombinant forms of these molecules are described as well as uses for them.
    Type: Grant
    Filed: February 19, 1998
    Date of Patent: April 4, 2000
    Inventors: Susanna M. Rybak, Dianne L. Newton, Lluis Boque, Alexander Wlodawer