Patents by Inventor Alexander Wright

Alexander Wright has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12378876
    Abstract: A drilling assembly for downhole to surface communications is provided. The drilling assembly includes a series of pipe segments coupled in fluid communication between a slip ring assembly and an end pipe portion. The slip ring assembly is coupled in data and fluid communication with the pipe segments. A surface communications link is in data communication with the drilling assembly via the slip ring assembly. An end pipe portion is coupled with the drilling assembly that includes an electronics assembly with electronic components for transferring data to the slip ring assembly via the drilling assembly. A drill bit is operably coupled with the end pipe portion for drilling a borehole. Each pipe segment includes an outer conductor portion, a hollow inner conductor portion, and a dielectric portion for electrical isolation between the outer conductor portion and the inner conductor portion.
    Type: Grant
    Filed: November 6, 2023
    Date of Patent: August 5, 2025
    Assignee: National Technology & Engineering Solutions of Sandia, LLC
    Inventors: Jiann-Cherng Su, Jason P. Krein, John Joseph Borchardt, Richard Ellis Robey, Andrew Alexander Wright, Joseph Samuel Pope, Taylor Anthony Myers, Mark C. Grubelich, Douglas A. Blankenship
  • Publication number: 20240150317
    Abstract: The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilising said intermediates. In particular, the present invention relates to chemical processes and intermediates useful in the manufacture of the compound 4-(4-bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)quinazoline.
    Type: Application
    Filed: March 7, 2023
    Publication date: May 9, 2024
    Applicant: Genzyme Corporation
    Inventors: Jorgen Blixt, Michael David Golden, Philip John Hogan, David Michael Glanville Martin, Francis Joseph Montgomery, Zakariya Patel, John David Pittam, George Joseph Sependa, Christopher John Squire, Nicholas Cartwright Alexander Wright
  • Publication number: 20240068363
    Abstract: A drilling assembly for downhole to surface communications is provided. The drilling assembly includes a series of pipe segments coupled in fluid communication between a slip ring assembly and an end pipe portion. The slip ring assembly is coupled in data and fluid communication with the pipe segments. A surface communications link is in data communication with the drilling assembly via the slip ring assembly. An end pipe portion is coupled with the drilling assembly that includes an electronics assembly with electronic components for transferring data to the slip ring assembly via the drilling assembly. A drill bit is operably coupled with the end pipe portion for drilling a borehole. Each pipe segment includes an outer conductor portion, a hollow inner conductor portion, and a dielectric portion for electrical isolation between the outer conductor portion and the inner conductor portion.
    Type: Application
    Filed: November 6, 2023
    Publication date: February 29, 2024
    Inventors: Jiann-Cherng Su, Jason P. Krein, John Joseph Borchardt, Richard Ellis Robey, Andrew Alexander Wright, Joseph Samuel Pope, Taylor Anthony Myers, Mark C. Grubelich, Douglas A. Blankenship
  • Patent number: 11808144
    Abstract: A drilling assembly for downhole to surface communications is provided. The drilling assembly includes a series of pipe segments coupled in fluid communication between a slip ring assembly and an end pipe portion. The slip ring assembly is coupled in data and fluid communication with the pipe segments. A surface communications link is in data communication with the drilling assembly via the slip ring assembly. An end pipe portion is coupled with the drilling assembly that includes an electronics assembly with electronic components for transferring data to the slip ring assembly via the drilling assembly. A drill bit is operably coupled with the end pipe portion for drilling a borehole. Each pipe segment includes an outer conductor portion, a hollow inner conductor portion, and a dielectric portion for electrical isolation between the outer conductor portion and the inner conductor portion.
    Type: Grant
    Filed: November 3, 2020
    Date of Patent: November 7, 2023
    Assignee: National Technology & Engineering Solutions of Sandia, LLC
    Inventors: Jiann-Cherng Su, Jason P. Krein, John Joseph Borchardt, Richard Ellis Robey, Andrew Alexander Wright, Joseph Samuel Pope, Taylor Anthony Myers, Mark C. Grubelich, Douglas A. Blankenship
  • Publication number: 20230068593
    Abstract: The present invention is directed to processes for making various polymorphs of tucatinib, designated herein as Form I, Form II, and Form III of tucatinib. These forms can then be used to prepare pharmaceutical formations containing tucatinib. Tucatinib is a tyrosine kinase inhibitor that is indicated for the treatment of breast cancer.
    Type: Application
    Filed: July 27, 2022
    Publication date: March 2, 2023
    Inventors: Thierry BONNAUD, Adam Ross PATTERSON, Zoe PRENTICE, Mark Alexander WRIGHT
  • Publication number: 20220033377
    Abstract: The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilising said intermediates. In particular, the present invention relates to chemical processes and intermediates useful in the manufacture of the compound 4-(4-bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)quinazoline.
    Type: Application
    Filed: November 2, 2020
    Publication date: February 3, 2022
    Applicant: Genzyme Corporation
    Inventors: Jorgen Blixt, Michael David Golden, Philip John Hogan, David Michael Glanville Martin, Francis Joseph Montgomery, Zakariya Patel, John David Pittam, George Joseph Sependa, Christopher John Squire, Nicholas Cartwright Alexander Wright
  • Publication number: 20190263782
    Abstract: The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilising said intermediates. In particular, the present invention relates to chemical processes and intermediates useful in the manufacture of the compound 4-(4-bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)quinazoline.
    Type: Application
    Filed: May 8, 2019
    Publication date: August 29, 2019
    Applicant: Genzyme Corporation
    Inventors: Jorgen Blixt, Michael David Golden, Philip John Hogan, David Michael Glanville Martin, Francis Joseph Montgomery, Zakariya Patel, John David Pittam, George Joseph Sependa, Christopher John Squire, Nicholas Cartwright Alexander Wright
  • Patent number: 10344015
    Abstract: The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilizing said intermediates. In particular, the present invention relates to chemical processes and intermediates useful in the manufacture of the compound 4-(4-bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)quinazoline.
    Type: Grant
    Filed: October 27, 2017
    Date of Patent: July 9, 2019
    Assignee: Genzyme Corporation
    Inventors: Jorgen Blixt, Michael David Golden, Philip John Hogan, David Michael Glanville Martin, Francis Joseph Montgomery, Zakariya Patel, John David Pittam, George Joseph Sependa, Christopher John Squire, Nicholas Cartwright Alexander Wright
  • Publication number: 20180118716
    Abstract: The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilising said intermediates. In particular, the present invention relates to chemical processes and intermediates useful in the manufacture of the compound 4-(4-bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)quinazoline.
    Type: Application
    Filed: October 27, 2017
    Publication date: May 3, 2018
    Applicant: Genzyme Corporation
    Inventors: Jorgen Blixt, Michael David Golden, Philip John Hogan, David Michael Glanville Martin, Francis Joseph Montgomery, Zakariya Patel, John David Pittam, George Joseph Sependa, Christopher John Squire, Nicholas Cartwright Alexander Wright
  • Patent number: 9815816
    Abstract: The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilizing said intermediates. In particular, the present invention relates to chemical processes and intermediates useful in the manufacture of the compound 4-(4-bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)quinazoline.
    Type: Grant
    Filed: July 22, 2015
    Date of Patent: November 14, 2017
    Assignee: Genzyme Corporation
    Inventors: Jorgen Blixt, Michael David Golden, Philip John Hogan, David Michael Glanville Martin, Francis Joseph Montgomery, Zakariya Patel, John David Pittam, George Joseph Sependa, Christopher John Squire, Nicholas Cartwright Alexander Wright
  • Publication number: 20160185754
    Abstract: The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilising said intermediates. In particular, the present invention relates to chemical processes and intermediates useful in the manufacture of the compound 4-(4-bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)quinazoline.
    Type: Application
    Filed: July 22, 2015
    Publication date: June 30, 2016
    Applicant: ASTRAZENECA AB
    Inventors: Jorgen BLIXT, Michael David GOLDEN, Philip John HOGAN, David Michael Glanville MARTIN, Francis Joseph MONTGOMERY, Zakariya PATEL, John David PITTAM, George Joseph SEPENDA, Christopher John SQUIRE, Nicholas Cartwright Alexander WRIGHT
  • Publication number: 20140378684
    Abstract: The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilising said intermediates. In particular, the present invention relates to chemical processes and intermediates useful in the manufacture of the compound 4-(4-bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)quinazoline.
    Type: Application
    Filed: September 9, 2014
    Publication date: December 25, 2014
    Applicant: ASTRAZENECA AB
    Inventors: Jorgen BLIXT, Michael David GOLDEN, Philip John HOGAN, David Michael Glanville MARTIN, Francis Joseph MONTGOMERY, Zakariya PATEL, John David PITTAM, George Joseph SEPENDA, Christopher John SQUIRE, Nicholas Cartwright Alexander WRIGHT
  • Patent number: 8865899
    Abstract: The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilising said intermediates.
    Type: Grant
    Filed: December 7, 2011
    Date of Patent: October 21, 2014
    Assignee: AstraZeneca AB
    Inventors: Jorgen Blixt, Michael David Golden, Philip John Hogan, David Michael Glanville Martin, Francis Joseph Montgomery, Zakariya Patel, John David Pittam, George Joseph Sependa, Christopher John Squire, Nicholas Cartwright Alexander Wright
  • Patent number: 8163926
    Abstract: The present invention relates to a process for the manufacture of a compound of the Formula IIa: wherein R is a suitable sulphonate ester; from a (C1-C6)alkyl-4-piperidinecarboxylate compound of the Formula III:
    Type: Grant
    Filed: September 27, 2006
    Date of Patent: April 24, 2012
    Assignee: AstraZeneca AB
    Inventors: Jorgen Blixt, Michael David Golden, Philip John Hogan, David Michael Glanville Martin, Francis Joseph Montgomery, Zakariya Patel, John David Pittam, George Joseph Sependa, Christopher John Squire, Nicholas Cartwright Alexander Wright
  • Publication number: 20120095229
    Abstract: The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilising said intermediates. In particular, the present invention relates to chemical processes and intermediates useful in the manufacture of the compound 4-(4-bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)quinazoline.
    Type: Application
    Filed: December 7, 2011
    Publication date: April 19, 2012
    Inventors: Jorgen BLIXT, Michael David GOLDEN, Philip John HOGAN, David Michael Glanville MARTIN, Francis Joseph MONTGOMERY, Zakariya PATEL, John David PITTAM, George Joseph SEPENDA, Christopher John SQUIRE, Nicholas Cartwright Alexander WRIGHT
  • Publication number: 20100208017
    Abstract: An imaging module includes an ink jet print head for printing human-readable or coded (e.g., bar code) information directly onto various porous and non-porous materials (e.g., a corrugated cardboard container), and a pair of reservoirs that hold the melted ink ultimately used in the printing process. The module also includes an ink feed hopper into which one or more solid sticks of hot melt wax ink are fed and an associated heater to melt the ink sticks in limited volume, together with associated vents, control pumps and valves, all integrated together within the imaging module to deliver the melted ink to the print head for printing on a container or other items.
    Type: Application
    Filed: February 19, 2010
    Publication date: August 19, 2010
    Applicant: BLACK DOT TECHNOLOGY, INC.
    Inventors: Richard N. Florence, Raymond J. MacQueen, JR., Elaine A. Pullen, Graham D. Walter, Robert L. Wiita, William Parker Alexander Wright
  • Publication number: 20090203905
    Abstract: The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilising said intermediates. In particular, the present invention relates to chemical processes and intermediates useful in the manufacture of the compound 4-(4-bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)quinazoline.
    Type: Application
    Filed: September 27, 2006
    Publication date: August 13, 2009
    Inventors: Jorgen Blixt, Michael David Golden, Philip John Hogan, David Michael Glanville Martin, Francis Joeph Montgomery, Zakariya Patel, John David Pittam, George Joseph Sependa, Christopher John Squire, Nicholas Cartwright Alexander Wright
  • Publication number: 20040170350
    Abstract: An improved bearing assembly (5) especially suitable for supporting a rotating shaft (2) or similar component which is subjected to a symmetrical or irregular loading; the bearing assembly (5) includes at least two coaxial rolling type bearings (6, 7) each of which is provided with one or more mounting seals (9, 10); each seal (9, 10) is a ring of resilient material arranged to contact the external circumference of the bearing (6, 7) so that each bearing (6, 7) is mounted upon the corresponding seal or seals (9, 10).
    Type: Application
    Filed: November 10, 2003
    Publication date: September 2, 2004
    Inventors: Steven Murray McCallum, William Alexander Wright
  • Patent number: 5156428
    Abstract: A janitorial implement for cleaning toilets, urinals and the like, and having a device for grasping soiled objects, the brush comprising a hollow handle device for operatively handling the brush, the handle device having an outer side wall and a hollow interior and having a slot to its outer side wall to the hollow interior, the handle device having a first end and a second end a pair of cooperating grasping device extending from the first end the grasping device being integrally connected to a handle extension device, the handle extension device being slidably mounted within the hollow interior an operating device connected to the extension device and extending through the slot for moving the extension device into an out of the hollow handle device spreading device operatively positioned at the second end, the spreading device including a spreader bar for enlarging the distance between the pair of grasping device when the extension device is moved outwardly from the hollow interior the spreading device inclu
    Type: Grant
    Filed: September 24, 1991
    Date of Patent: October 20, 1992
    Inventor: Alexander Wright
  • Patent number: D1081682
    Type: Grant
    Filed: December 21, 2022
    Date of Patent: July 1, 2025
    Assignee: ROCHE MOLECULAR SYSTEMS, INC.
    Inventors: Angus Hyland, Shirley Wang, Karolina Alvekrans, Alexander Wright