Patents by Inventor Alexander Wright
Alexander Wright has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12378876Abstract: A drilling assembly for downhole to surface communications is provided. The drilling assembly includes a series of pipe segments coupled in fluid communication between a slip ring assembly and an end pipe portion. The slip ring assembly is coupled in data and fluid communication with the pipe segments. A surface communications link is in data communication with the drilling assembly via the slip ring assembly. An end pipe portion is coupled with the drilling assembly that includes an electronics assembly with electronic components for transferring data to the slip ring assembly via the drilling assembly. A drill bit is operably coupled with the end pipe portion for drilling a borehole. Each pipe segment includes an outer conductor portion, a hollow inner conductor portion, and a dielectric portion for electrical isolation between the outer conductor portion and the inner conductor portion.Type: GrantFiled: November 6, 2023Date of Patent: August 5, 2025Assignee: National Technology & Engineering Solutions of Sandia, LLCInventors: Jiann-Cherng Su, Jason P. Krein, John Joseph Borchardt, Richard Ellis Robey, Andrew Alexander Wright, Joseph Samuel Pope, Taylor Anthony Myers, Mark C. Grubelich, Douglas A. Blankenship
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Publication number: 20240150317Abstract: The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilising said intermediates. In particular, the present invention relates to chemical processes and intermediates useful in the manufacture of the compound 4-(4-bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)quinazoline.Type: ApplicationFiled: March 7, 2023Publication date: May 9, 2024Applicant: Genzyme CorporationInventors: Jorgen Blixt, Michael David Golden, Philip John Hogan, David Michael Glanville Martin, Francis Joseph Montgomery, Zakariya Patel, John David Pittam, George Joseph Sependa, Christopher John Squire, Nicholas Cartwright Alexander Wright
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Publication number: 20240068363Abstract: A drilling assembly for downhole to surface communications is provided. The drilling assembly includes a series of pipe segments coupled in fluid communication between a slip ring assembly and an end pipe portion. The slip ring assembly is coupled in data and fluid communication with the pipe segments. A surface communications link is in data communication with the drilling assembly via the slip ring assembly. An end pipe portion is coupled with the drilling assembly that includes an electronics assembly with electronic components for transferring data to the slip ring assembly via the drilling assembly. A drill bit is operably coupled with the end pipe portion for drilling a borehole. Each pipe segment includes an outer conductor portion, a hollow inner conductor portion, and a dielectric portion for electrical isolation between the outer conductor portion and the inner conductor portion.Type: ApplicationFiled: November 6, 2023Publication date: February 29, 2024Inventors: Jiann-Cherng Su, Jason P. Krein, John Joseph Borchardt, Richard Ellis Robey, Andrew Alexander Wright, Joseph Samuel Pope, Taylor Anthony Myers, Mark C. Grubelich, Douglas A. Blankenship
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Patent number: 11808144Abstract: A drilling assembly for downhole to surface communications is provided. The drilling assembly includes a series of pipe segments coupled in fluid communication between a slip ring assembly and an end pipe portion. The slip ring assembly is coupled in data and fluid communication with the pipe segments. A surface communications link is in data communication with the drilling assembly via the slip ring assembly. An end pipe portion is coupled with the drilling assembly that includes an electronics assembly with electronic components for transferring data to the slip ring assembly via the drilling assembly. A drill bit is operably coupled with the end pipe portion for drilling a borehole. Each pipe segment includes an outer conductor portion, a hollow inner conductor portion, and a dielectric portion for electrical isolation between the outer conductor portion and the inner conductor portion.Type: GrantFiled: November 3, 2020Date of Patent: November 7, 2023Assignee: National Technology & Engineering Solutions of Sandia, LLCInventors: Jiann-Cherng Su, Jason P. Krein, John Joseph Borchardt, Richard Ellis Robey, Andrew Alexander Wright, Joseph Samuel Pope, Taylor Anthony Myers, Mark C. Grubelich, Douglas A. Blankenship
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Publication number: 20230068593Abstract: The present invention is directed to processes for making various polymorphs of tucatinib, designated herein as Form I, Form II, and Form III of tucatinib. These forms can then be used to prepare pharmaceutical formations containing tucatinib. Tucatinib is a tyrosine kinase inhibitor that is indicated for the treatment of breast cancer.Type: ApplicationFiled: July 27, 2022Publication date: March 2, 2023Inventors: Thierry BONNAUD, Adam Ross PATTERSON, Zoe PRENTICE, Mark Alexander WRIGHT
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Publication number: 20220033377Abstract: The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilising said intermediates. In particular, the present invention relates to chemical processes and intermediates useful in the manufacture of the compound 4-(4-bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)quinazoline.Type: ApplicationFiled: November 2, 2020Publication date: February 3, 2022Applicant: Genzyme CorporationInventors: Jorgen Blixt, Michael David Golden, Philip John Hogan, David Michael Glanville Martin, Francis Joseph Montgomery, Zakariya Patel, John David Pittam, George Joseph Sependa, Christopher John Squire, Nicholas Cartwright Alexander Wright
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Publication number: 20190263782Abstract: The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilising said intermediates. In particular, the present invention relates to chemical processes and intermediates useful in the manufacture of the compound 4-(4-bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)quinazoline.Type: ApplicationFiled: May 8, 2019Publication date: August 29, 2019Applicant: Genzyme CorporationInventors: Jorgen Blixt, Michael David Golden, Philip John Hogan, David Michael Glanville Martin, Francis Joseph Montgomery, Zakariya Patel, John David Pittam, George Joseph Sependa, Christopher John Squire, Nicholas Cartwright Alexander Wright
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Patent number: 10344015Abstract: The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilizing said intermediates. In particular, the present invention relates to chemical processes and intermediates useful in the manufacture of the compound 4-(4-bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)quinazoline.Type: GrantFiled: October 27, 2017Date of Patent: July 9, 2019Assignee: Genzyme CorporationInventors: Jorgen Blixt, Michael David Golden, Philip John Hogan, David Michael Glanville Martin, Francis Joseph Montgomery, Zakariya Patel, John David Pittam, George Joseph Sependa, Christopher John Squire, Nicholas Cartwright Alexander Wright
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Publication number: 20180118716Abstract: The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilising said intermediates. In particular, the present invention relates to chemical processes and intermediates useful in the manufacture of the compound 4-(4-bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)quinazoline.Type: ApplicationFiled: October 27, 2017Publication date: May 3, 2018Applicant: Genzyme CorporationInventors: Jorgen Blixt, Michael David Golden, Philip John Hogan, David Michael Glanville Martin, Francis Joseph Montgomery, Zakariya Patel, John David Pittam, George Joseph Sependa, Christopher John Squire, Nicholas Cartwright Alexander Wright
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Patent number: 9815816Abstract: The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilizing said intermediates. In particular, the present invention relates to chemical processes and intermediates useful in the manufacture of the compound 4-(4-bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)quinazoline.Type: GrantFiled: July 22, 2015Date of Patent: November 14, 2017Assignee: Genzyme CorporationInventors: Jorgen Blixt, Michael David Golden, Philip John Hogan, David Michael Glanville Martin, Francis Joseph Montgomery, Zakariya Patel, John David Pittam, George Joseph Sependa, Christopher John Squire, Nicholas Cartwright Alexander Wright
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Publication number: 20160185754Abstract: The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilising said intermediates. In particular, the present invention relates to chemical processes and intermediates useful in the manufacture of the compound 4-(4-bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)quinazoline.Type: ApplicationFiled: July 22, 2015Publication date: June 30, 2016Applicant: ASTRAZENECA ABInventors: Jorgen BLIXT, Michael David GOLDEN, Philip John HOGAN, David Michael Glanville MARTIN, Francis Joseph MONTGOMERY, Zakariya PATEL, John David PITTAM, George Joseph SEPENDA, Christopher John SQUIRE, Nicholas Cartwright Alexander WRIGHT
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Publication number: 20140378684Abstract: The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilising said intermediates. In particular, the present invention relates to chemical processes and intermediates useful in the manufacture of the compound 4-(4-bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)quinazoline.Type: ApplicationFiled: September 9, 2014Publication date: December 25, 2014Applicant: ASTRAZENECA ABInventors: Jorgen BLIXT, Michael David GOLDEN, Philip John HOGAN, David Michael Glanville MARTIN, Francis Joseph MONTGOMERY, Zakariya PATEL, John David PITTAM, George Joseph SEPENDA, Christopher John SQUIRE, Nicholas Cartwright Alexander WRIGHT
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Patent number: 8865899Abstract: The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilising said intermediates.Type: GrantFiled: December 7, 2011Date of Patent: October 21, 2014Assignee: AstraZeneca ABInventors: Jorgen Blixt, Michael David Golden, Philip John Hogan, David Michael Glanville Martin, Francis Joseph Montgomery, Zakariya Patel, John David Pittam, George Joseph Sependa, Christopher John Squire, Nicholas Cartwright Alexander Wright
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Patent number: 8163926Abstract: The present invention relates to a process for the manufacture of a compound of the Formula IIa: wherein R is a suitable sulphonate ester; from a (C1-C6)alkyl-4-piperidinecarboxylate compound of the Formula III:Type: GrantFiled: September 27, 2006Date of Patent: April 24, 2012Assignee: AstraZeneca ABInventors: Jorgen Blixt, Michael David Golden, Philip John Hogan, David Michael Glanville Martin, Francis Joseph Montgomery, Zakariya Patel, John David Pittam, George Joseph Sependa, Christopher John Squire, Nicholas Cartwright Alexander Wright
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Publication number: 20120095229Abstract: The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilising said intermediates. In particular, the present invention relates to chemical processes and intermediates useful in the manufacture of the compound 4-(4-bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)quinazoline.Type: ApplicationFiled: December 7, 2011Publication date: April 19, 2012Inventors: Jorgen BLIXT, Michael David GOLDEN, Philip John HOGAN, David Michael Glanville MARTIN, Francis Joseph MONTGOMERY, Zakariya PATEL, John David PITTAM, George Joseph SEPENDA, Christopher John SQUIRE, Nicholas Cartwright Alexander WRIGHT
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Publication number: 20100208017Abstract: An imaging module includes an ink jet print head for printing human-readable or coded (e.g., bar code) information directly onto various porous and non-porous materials (e.g., a corrugated cardboard container), and a pair of reservoirs that hold the melted ink ultimately used in the printing process. The module also includes an ink feed hopper into which one or more solid sticks of hot melt wax ink are fed and an associated heater to melt the ink sticks in limited volume, together with associated vents, control pumps and valves, all integrated together within the imaging module to deliver the melted ink to the print head for printing on a container or other items.Type: ApplicationFiled: February 19, 2010Publication date: August 19, 2010Applicant: BLACK DOT TECHNOLOGY, INC.Inventors: Richard N. Florence, Raymond J. MacQueen, JR., Elaine A. Pullen, Graham D. Walter, Robert L. Wiita, William Parker Alexander Wright
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Publication number: 20090203905Abstract: The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilising said intermediates. In particular, the present invention relates to chemical processes and intermediates useful in the manufacture of the compound 4-(4-bromo-2-fluoroanilino)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)quinazoline.Type: ApplicationFiled: September 27, 2006Publication date: August 13, 2009Inventors: Jorgen Blixt, Michael David Golden, Philip John Hogan, David Michael Glanville Martin, Francis Joeph Montgomery, Zakariya Patel, John David Pittam, George Joseph Sependa, Christopher John Squire, Nicholas Cartwright Alexander Wright
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Publication number: 20040170350Abstract: An improved bearing assembly (5) especially suitable for supporting a rotating shaft (2) or similar component which is subjected to a symmetrical or irregular loading; the bearing assembly (5) includes at least two coaxial rolling type bearings (6, 7) each of which is provided with one or more mounting seals (9, 10); each seal (9, 10) is a ring of resilient material arranged to contact the external circumference of the bearing (6, 7) so that each bearing (6, 7) is mounted upon the corresponding seal or seals (9, 10).Type: ApplicationFiled: November 10, 2003Publication date: September 2, 2004Inventors: Steven Murray McCallum, William Alexander Wright
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Patent number: 5156428Abstract: A janitorial implement for cleaning toilets, urinals and the like, and having a device for grasping soiled objects, the brush comprising a hollow handle device for operatively handling the brush, the handle device having an outer side wall and a hollow interior and having a slot to its outer side wall to the hollow interior, the handle device having a first end and a second end a pair of cooperating grasping device extending from the first end the grasping device being integrally connected to a handle extension device, the handle extension device being slidably mounted within the hollow interior an operating device connected to the extension device and extending through the slot for moving the extension device into an out of the hollow handle device spreading device operatively positioned at the second end, the spreading device including a spreader bar for enlarging the distance between the pair of grasping device when the extension device is moved outwardly from the hollow interior the spreading device incluType: GrantFiled: September 24, 1991Date of Patent: October 20, 1992Inventor: Alexander Wright
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Patent number: D1081682Type: GrantFiled: December 21, 2022Date of Patent: July 1, 2025Assignee: ROCHE MOLECULAR SYSTEMS, INC.Inventors: Angus Hyland, Shirley Wang, Karolina Alvekrans, Alexander Wright