Patents by Inventor Alexander Y. Rudensky

Alexander Y. Rudensky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DEPLETING TUMOR-SPECIFIC TREGS
    Publication number: 20210364520
    Abstract: The present invention provides, among other things, methods and compositions for diagnosing and/or treating cancer by targeting CCR8. In particular, the present invention provides technologies for depleting Treg cells, and particularly tumor-infiltrating Treg cells.
    Type: Application
    Filed: August 5, 2021
    Publication date: November 25, 2021
    Inventors: Alexander Y. Rudensky, George Plitas
  • REGULATORY T CELL POPULATIONS
    Publication number: 20190376030
    Abstract: The present disclosure provides regulatory T cells and regulatory T cell populations engineered to express a transcription factor. The present disclosure provides for treatment of immune disorders with regulatory T cells and regulatory T cell populations engineered to express a transcription factor.
    Type: Application
    Filed: June 6, 2019
    Publication date: December 12, 2019
    Inventors: Alexander Y. Rudensky, Andrew G. Levine
  • ENGINEERED TREG CELLS
    Publication number: 20190322983
    Abstract: The present invention provides, among other things, methods and compositions for modulating or treating inflammatory and autoimmune diseases, disorders, and conditions. The present invention is based, in part, on the surprising discovery that engineered regulatory T-cells characterized by constitutive STAT activity are efficacious in treating disease.
    Type: Application
    Filed: June 15, 2017
    Publication date: October 24, 2019
    Inventors: Alexander Y. Rudensky, Takatoshi Chinen
  • DEPLETING TUMOR-SPECIFIC TREGS
    Publication number: 20190092875
    Abstract: The present invention provides, among other things, methods and compositions for diagnosing and/or treating cancer by targeting CCR8. In particular, the present invention provides technologies for depleting Treg cells, and particularly tumor-infiltrating Treg cells.
    Type: Application
    Filed: August 29, 2018
    Publication date: March 28, 2019
    Inventors: Alexander Y. Rudensky, George Plitas