Patents by Inventor Alexander Y. TRICK

Alexander Y. TRICK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND RELATED ASPECTS FOR MULTIPLEXED ANALYTE DETECTION USING SEQUENTIAL MAGNETIC PARTICLE ELUTION
    Publication number: 20240123447
    Abstract: Provided herein are magnetofluidic cartridges of use in a wide variety of sample analysis applications, including nucleic acid amplification assays. The magnetofluidic cartridges include sample inlet wells and sample analysis wells for performing controlled serial elution techniques that enables execution of extraction/purification and splitting of analytes for multiplex detection via magnetic actuation only. Related magnetofluidic devices, kits, and methods are also provided.
    Type: Application
    Filed: January 28, 2022
    Publication date: April 18, 2024
    Applicant: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Tza-Huei Jeff WANG, Alexander Y. TRICK, Fan-En CHEN, Liben CHEN
  • MAGNETOFLUIDIC CARTRIDGES, DEVICES AND RELATED METHODS OF SAMPLE ANALYSIS
    Publication number: 20230201833
    Abstract: Provided herein are magnetofluidic cartridges of use in a wide variety of sample analysis applications, including nucleic acid amplification assays. The magnetofluidic cartridges include sample inlet wells and sample analysis wells. Temperature sensitive materials are used to separate the sample inlet wells and sample analysis wells from one another prior to performing a given sample analysis application. Related magnetofluidic devices, kits, and methods are also provided.
    Type: Application
    Filed: May 27, 2021
    Publication date: June 29, 2023
    Applicant: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Tza-Huei Jeff WANG, Alexander Y. TRICK, Fan-En CHEN
  • METHODS AND RELATED ASPECTS FOR QUANTITATIVE RATIOMETRIC REGRESSION POLYMERASE CHAIN REACTION
    Publication number: 20210343364
    Abstract: Provided herein are methods of performing multiplexed real-time quantitative ratiometric regression PCR (qRR-PCR) to determine the fractional abundance of target variants in a population. Related systems and computer program products are also provided.
    Type: Application
    Filed: April 23, 2021
    Publication date: November 4, 2021
    Inventors: Tza-Huei Jeff Wang, Alexander Y. Trick
  • METHODS AND RELATED ASPECTS FOR QUANTITATIVE POLYMERASE CHAIN REACTION TO DETERMINE FRACTIONAL ABUNDANCE
    Publication number: 20210340633
    Abstract: Provided herein are methods of processing grain samples to detect the fractional abundance of transgenic traits. Related systems and computer program products are also provided.
    Type: Application
    Filed: April 23, 2021
    Publication date: November 4, 2021
    Inventors: Tza-Huei Jeff Wang, Alexander Y. Trick, Xiaoyi Sopko
  • DISPOSABLE REAGENT SCAFFOLD FOR BIOCHEMICAL PROCESS INTEGRATION
    Publication number: 20210114036
    Abstract: Devices for assaying a biomolecule from a sample, including: a cartridge assembly structured to accept and secure a magnetofluidic cartridge to be used for the assaying, and a magnetic particle manipulation assembly arranged proximate the cartridge assembly, the magnetic particle manipulation assembly having a pair of magnets arranged to be on opposing sides of said magnetofluidic cartridge and which are substantially aligned along a line that will be transverse to the magnetofluidic cartridge such that the line can be aligned with a well in the magnetofluidic cartridge, and methods of using and assembling such devices.
    Type: Application
    Filed: April 30, 2019
    Publication date: April 22, 2021
    Applicant: The Johns Hopkins University
    Inventors: Tza-Huei Wang, Dong Jin SHIN, Alexander Y. TRICK