Abstract: The invention discloses peptides having biocidal properties, more particularly antibacterial, antifungal, and antiviral properties, and preparations based thereon. A biocidal peptide of general formula Y-Ile-Leu-Pro-X-Lys-X-Pro-X-X-Pro-X-Arg-Arg-NH2, where X is 4-nitrophenylalanine; 4-chlorophenylalanine; 4-methoxyphenylalanine; D-phenylalanine; 4-aminophenylalanine; 4-aminobenzoylphenylalanine; homophenylalanine; 4-tertbutylphenylalanine; 2-methylphenylalanine; 4-fluorophenyl alanine; pentafluorophenylalanine; or 2-trifluoromethylphenylalanine; and Y is H or palmitoyl or aminoundecanoyl, and a preparation in the form of a gel with biocidal properties, containing, as an active substance, the peptide at a concentration of 0.001 to 0.1 wt %. The peptides demonstrate biocidal properties towards bacteria, including spore-forming bacteria, mold fungi, and viruses. The peptide-based gels can be used for treating bacterial and viral infectious diseases and infectious comorbidities.

Abstract: The invention includes a tetrapeptide to be used in the treatment of Alzheimer's disease and depression. The tetrapeptide comprises the general formula, acetyl-X-ARG-ARG-amide, where X=-(D-ARG)-ARG-; -(D-LYS)-LYS-; or -(D-MET)-MET-. On the basis of the combination of pharmacological properties identified, a preparation including the tetrapeptide has potential for clinical use as a nootropic, neuroprotective, and antidepressant agent.

Abstract: The invention relates to medicine, and more particularly to neurology, and can be used in the treatment of Alzheimer's disease and depression. A peptide is proposed having the general formula acetyl-X-ARG-ARG-amide, where X=-(D-ARG)-ARG-; -(D-LYS)-LYS- or -(D-MET)-MET-. On the basis of the combination of pharmacological properties identified, a preparation could have potential for future clinical use as a nootropic, neuroprotective and antidepressant agent.

Abstract: The invention relates to the field of medicine, in particular to novel peptides having biocidal properties, more particularly antibacterial, antifungal and antiviral properties, and preparations based thereon. Proposed are a biocidal peptide of general formula Y-Ile-Leu-Pro-X-Lys-X-Pro-X-X-Pro-X-Arg-Arg-NH2, where X is 4-nitrophenylalanine; 4-chlorophenylalanine; 4-methoxyphenylalanine; D-phenylalanine; 4-aminophenylalanine; 4-aminobenzoylphenylalanine; homophenylalanine; 4-tertbutylphenylalanine; 2-methylphenylalanine; 4-fluorophenyl alanine; pentafluorophenylalanine; or 2-trifluoromethylphenylalanine; and Y is H or palmitoyl or aminodecanoyl, and a preparation in the form of a gel with biocidal properties, containing, as an active substance, said peptide at a concentration of 0.001 to 0.1 wt %. The claimed peptides demonstrate biocidal properties towards bacteria, including spore-forming bacteria, mould fungi, and also viruses.

Abstract: The invention relates to medicine, specifically to new medicinal compositions that exhibit a biocidal, particularly antimicrobial and antiviral, effect. An agent is proposed that contains an alloferon analogue—the peptide H2N-His-Gly-Val-Ser-Gly-His-Gly-Gln-His-Gly-Val-His-Gly-COOH and the peptide HN2-(CH2)10-CO-Ile-Leu-Pro-D-Phe-Lys-D-Phe-Pro-D-Phe-D-Phe-Pro-D-Phe-Arg-Arg-NH2 in a mass ratio from 1:2 to 2:1 and excipients. The agent exhibits a combined antibacterial and antiviral effect and is promising for the treatment of vaginal herpes infection, including when complicated by bacterial infection.