Abstract: In some examples, a catheter system includes an elongate shaft including a distal portion and a proximal portion and a neuromodulation element on the distal portion of the elongate shaft. The proximal portion of the shaft can include a proximal hypotube segment defining an inner lumen, and an electrically insulative tube located at least partially within the inner lumen of the proximal hypotube segment, the electrically insulative tube being attached to the proximal hypotube segment at at least one of a proximal portion or a distal portion of the proximal hypotube segment. The catheter system can also include one or more electrical leads extending distally within the inner lumen of the proximal hypotube segment and the electrically insulative tube to the neuromodulation element on the distal portion of the elongate shaft.

Abstract: A catheter configured to deliver energy circumferentially around an anatomical lumen in which the catheter is positioned. The catheter includes an elongate structure configured to transform between a low-profile delivery state and a radially expanded deployed state. The elongate structure mechanically supports one or more electrodes configured to emit energy and includes an outer jacket comprising a polymer. The catheter defines a material boundary adjoining the outer jacket and at least one electrode to enable a mechanical adhesion between the polymer of the outer jacket and the electrode. In examples, the polymer intrudes into one or more volumes defined by asperities in a surface of the electrode to enable the mechanical adhesion. In examples, material boundary is formed by reflowing the polymer.

Abstract: A catheter includes a metal hypotube (328) and a polymer outer jacket over the metal hypotube, wherein the metal hypotube is configured to bend with varying flexibility along a length of the metal hypotube, and wherein the metal hypotube defines a rapid exchange joint opening in an intermediate portion of the metal hypotube. A method for manufacturing a catheter includes cutting a rapid exchange joint opening in an intermediate portion of a metal hypotube and a polymer jacket over the metal hypotube, wherein the rapid exchange joint opening facilitates formation of a rapid exchange joint, and the metal hypotube is configured to bend with varying flexibility along a length of the metal hypotube.

Abstract: Aspects of the disclosure include delivery devices for transcatheter delivery of a cardiac implant. Delivery devices can include a handle assembly as well as a piston mount connected to the handle assembly and having a distal portion terminating at a nose cap. The distal portion includes a stop extending radially from and fixed to the distal portion. The delivery device further includes a capsule assembly including a biasing element for selectively sheathing the implant and a plurality of retraction members secured about a distal end of the biasing element to control deployment of the implant. In various examples, the biasing element is a helical compression spring and the implant is a prosthetic tricuspid heart valve. Methods of loading a delivery device and delivering an implant are also disclosed.