Patents by Inventor Alexandra L. Rutz

Alexandra L. Rutz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Artificial ovary
    Patent number: 10479980
    Abstract: Artificial ovaries comprising porous three-dimensional scaffolds are provided. Also provided are ink compositions and methods for printing the scaffolds. The artificial ovaries have spatial arrangements and cellular compositions that allow them to mimic native ovarian tissue. As such, they can be cultured or transplanted to support female endocrine function and/or the development of oocytes and/or eggs.
    Type: Grant
    Filed: January 28, 2016
    Date of Patent: November 19, 2019
    Assignee: NORTHWESTERN UNIVERSITY
    Inventors: Monica M. Laronda, Alexandra L. Rutz, Ramille N. Shah, Teresa K. Woodruff
  • Poly(ethylene glycol) cross-linking of soft materials to tailor viscoelastic properties for bioprinting
    Patent number: 10173357
    Abstract: Extrudable hydrogel compositions for printing 3D objects, such as cell growth scaffolds, are provided. Also provided are methods for making the crosslinked hydrogel compositions and the printed objects and methods for culturing cells using the cell growth scaffolds. The hydrogel precursor solutions are aqueous solutions comprising a biocompatible polymer, functionalized polyethylene glycol as a crosslinker and, optionally, cells and/or bioactive factors.
    Type: Grant
    Filed: September 25, 2014
    Date of Patent: January 8, 2019
    Assignee: Northwestern University
    Inventors: Alexandra L. Rutz, Ramille N. Shah
  • ARTIFICIAL OVARY
    Publication number: 20170369851
    Abstract: Artificial ovaries comprising porous three-dimensional scaffolds are provided. Also provided are ink compositions and methods for printing the scaffolds. The artificial ovaries have spatial arrangements and cellular compositions that allow them to mimic native ovarian tissue. As such, they can be cultured or transplanted to support female endocrine function and/or the development of oocytes and/or eggs.
    Type: Application
    Filed: January 28, 2016
    Publication date: December 28, 2017
    Inventors: Monica M. Laronda, Alexandra L. Rutz, Ramille N. Shah, Teresa K. Woodruff
  • POLY(ETHYLENE GLYCOL) CROSS-LINKING OF SOFT MATERIALS TO TAILOR VISCOELASTIC PROPERTIES FOR BIOPRINTING
    Publication number: 20150084232
    Abstract: Extrudable hydrogel compositions for printing 3D objects, such as cell growth scaffolds, are provided. Also provided are methods for making the crosslinked hydrogel compositions and the printed objects and methods for culturing cells using the cell growth scaffolds. The hydrogel precursor solutions are aqueous solutions comprising a biocompatible polymer, functionalized polyethylene glycol as a crosslinker and, optionally, cells and/or bioactive factors.
    Type: Application
    Filed: September 25, 2014
    Publication date: March 26, 2015
    Inventors: Alexandra L. Rutz, Ramille N. Shah