Patents by Inventor Alexandra Lucas

Alexandra Lucas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chemokine binding protein and methods of use therefor
    Patent number: 6495515
    Abstract: The present invention provides a method of use for a novel type I chemokine binding protein encoded by poxviruses and having amino acid sequence homology with the myxoma virus T7 interferon-&ggr; receptor homolog against disease syndromes associated with acute or chronic dysregulated inflammatory responses.
    Type: Grant
    Filed: September 14, 1999
    Date of Patent: December 17, 2002
    Assignee: Viron Therapeutics, Inc.
    Inventors: Grant McFadden, Alexandra Lucas
  • Methods of treating inflammation and compositions therefor
    Patent number: 5939525
    Abstract: Compositions and methods for treating inflammatory cell infiltration in a tissue of a mammalian subject are provided. The method involves administering a therapeutically effective amount of SERP-1, SERP-1 analog or biologically active fragment thereof admixed with a pharmaceutically acceptable carrier to a subject in need of such treatment. Biologically active SERP-1 analogs are also provided. The compositions and methods of the present invention are useful for treating numerous inflammatory based diseases and injuries.
    Type: Grant
    Filed: March 27, 1995
    Date of Patent: August 17, 1999
    Assignee: Viron Therapeutics, Inc.
    Inventors: D. Grant McFadden, Alexandra Lucas
  • Methods of treating inflammation and compositions therefor
    Patent number: 5917014
    Abstract: Compositions and methods for treating inflammatory cell infiltration in a tissue of a mammalian subject are provided. The method involves administering a therapeutically effective amount of SERP-1, SERP-1 analog or biologically active fragment thereof admixed with a pharmaceutically acceptable carrier to a subject in need of such treatment. Biologically active SERP-1 analogs are also provided. The compositions and methods of the present invention are useful for treating numerous inflammatory based diseases and injuries.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: June 29, 1999
    Assignee: Viron Therapeutics, Inc.
    Inventors: D. Grant McFadden, Alexandra Lucas
  • Chemokine binding protein and methods of use therefor
    Patent number: 5834419
    Abstract: The present invention provides a method of use for a novel type I chemokine binding protein encoded by poxviruses and having amino acid sequence homology with the myxoma virus T7 interferon-.gamma. receptor homolog against disease syndromes associated with acute or chronic dysregulated inflammatory responses.
    Type: Grant
    Filed: April 19, 1996
    Date of Patent: November 10, 1998
    Assignee: The John P. Robarts Institute
    Inventors: Grant McFadden, Alexandra Lucas
  • Antirestenosis protein
    Patent number: 5686409
    Abstract: A method of treating primary and recurrent atheromatous plaque development is provided. The method involves administering a therapeutically effective amount of SERP-1, admixed in a pharmaceutically acceptable carrier to the intimal or lumenal layer of arterial walls. Biologically active SERP-1 analogs are also provided.
    Type: Grant
    Filed: May 2, 1994
    Date of Patent: November 11, 1997
    Assignee: Research Corporation Technologies, Inc.
    Inventors: D. Grant McFadden, Alexandra Lucas