Patents by Inventor Alexandra Vernaleken

Alexandra Vernaleken has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tripeptides that down regulate the activity of plasma membrane transporters including sodium-D-glucose cotransporter SgIt1
    Patent number: 9155778
    Abstract: A regulatory protein RS1 fragment or a nucleic acid molecule encoding the regulatory protein RS1 fragment for the preparation of a pharmaceutical composition, food and/or food supplements for the amelioration, prevention and/or treatment of a metabolic disease or a secondary disorder caused by a (pathological) modification of homeostasis, wherein the RS1 fragment is characterized in comprising at least the amino acid sequence Q-C-P Glutamine-Cysteine-Proline) or derivatives thereof, is provided. Also provided is a method for the amelioration, prevention and/or treatment of a metabolic disease or a secondary disorder caused by a (pathological) modification of homeostasis comprising administering a pharmaceutically active amount of a regulatory protein RS1 fragment or a nucleic acid molecule encoding a regulatory protein RS1 fragment, wherein the RS1 fragment comprises at least the amino acid sequence Q-C-P or derivatives thereof.
    Type: Grant
    Filed: March 31, 2006
    Date of Patent: October 13, 2015
    Assignee: JULIUS-MAXMILLIANS-UNIVERSITAT WURZBURG
    Inventors: Hermann Koepsell, Alexandra Vernaleken
  • Peptides that down regulate the activity of plasma membrane transporters including sodium-D-glucose cotransporter SGLT1
    Patent number: 8207133
    Abstract: The present invention relates to the use of a regulatory protein RS1 fragment or a nucleic acid molecule encoding said regulatory protein RS1 fragment for the preparation of a pharmaceutical composition for the amelioration, prevention and/or treatment of a metabolic disease or a secondary disorder caused by a (pathological) modification of homeostasis, wherein said RS1 fragment is characterized in comprising at least 3 consecutive amino acid residues as comprised in the amino acid sequence S-D-S-D-R-I-E-P (Serine-Aspartic acid-Serine-Aspartic acid-Arginine-Isoleucine-Glutamic acid-Proline) (SEQ ID NO: 9) or derivatives thereof.
    Type: Grant
    Filed: March 31, 2006
    Date of Patent: June 26, 2012
    Assignee: Julius-Maximilians-Universitat Wurzburg
    Inventors: Herman Koepsell, Alexandra Vernaleken
  • PEPTIDES THAT DOWN REGULATE THE ACTIVITY OF PLASMA MEMBRANE TRANSPORTERS INCLUDING SODIUM-D-GLUCOSE COTRANSPORTER SGLT1
    Publication number: 20120148673
    Abstract: The present invention relates to the use of a regulatory protein RS1 fragment or a nucleic acid molecule encoding said regulatory protein RS1 fragment for the preparation of a pharmaceutical composition for the amelioration, prevention and/or treatment of a metabolic disease or a secondary disorder caused by a (pathological) modification of homeostasis, wherein said RS1 fragment is characterized in comprising at least 3 consecutive amino acid residues as comprised in the amino acid sequence S-D-S-D-R-I-E-P (Serine-Aspartic acid-Serine-Aspartic acid-Arginine-Isoleucine-Glutamic acid-Proline) (SEQ ID NO: 9) or derivatives thereof.
    Type: Application
    Filed: March 31, 2006
    Publication date: June 14, 2012
    Inventors: Hermann Koepsell, Alexandra Vernaleken
  • Tripeptides that Down Regulate the Activity of Plasma Membrane transporters Including Sodium-D-Glucose Cotransporter Sglt1
    Publication number: 20090203621
    Abstract: The present invention relates to the use of a regulatory protein RS1 fragment or a nucleic acid molecule encoding said regulatory protein RS1 fragment for the preparation of a pharmaceutical composition for the amelioration, prevention and/or treatment of a metabolic disease or a secondary disorder caused by a (pathological) modification of homeostasis, wherein said RS1 fragment is characterized in comprising at least the amino acid sequence Q-C-P (Glutamine-Cysteine-Proline) or derivatives thereof.
    Type: Application
    Filed: March 31, 2006
    Publication date: August 13, 2009
    Inventors: Hermann Koepsell, Alexandra Vernaleken