Patents by Inventor Alexandre Alanio

Alexandre Alanio has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MEANS FOR DIAGNOSING, PREDICTING OR MONITORING PNEUMOCYSTIS PNEUMONIA
    Publication number: 20220119886
    Abstract: The application relates to means for diagnosing, predicting or monitoring Pneumocystis pneumonia (PCP). The means of the application are also suitable for determining or predicting the efficacy of a drug or treatment against PCP in a human patient. The means of involve the detection and/or quantification, more particularly the quantification, of the RNA transcripts of two different P. jirovecii mitochondrial genes. The first of said two P. jirovecii mitochondrial genes is the P. jirovecii gene, the sequence of which codes for the Cytb protein or the P. jirovecii mitochondrial Small Sub-Unit (mtSSU) gene. The second of said two P. jirovecii mitochondrial genes is a P. jirovecii gene, the sequence of which transcribes into a P. jirovecii ribosomal RNA, e.g., be the mitochondrial P. jirovecii Large Sub-Unit (mtLSU) gene.
    Type: Application
    Filed: December 15, 2021
    Publication date: April 21, 2022
    Applicants: INSTITUT PASTEUR, ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS, UNIVERSITE PARIS DIDEROT - PARIS 7
    Inventors: Alexandre ALANIO, Stephane BRETAGNE, Francoise DROMER, Aude STURNY-LECLERE, Benjamin HOMMEL, Marion BENAZRA
  • Means for diagnosing, predicting or monitoring pneumonia
    Patent number: 11236390
    Abstract: The application relates to means for diagnosing, predicting or monitoring Pneumocystis pneumonia (PCP). The means of the application are also suitable for determining or predicting the efficacy of a drug or treatment against PCP in a human patient. The means of involve the detection and/or quantification, more particularly the quantification, of the RNA transcripts of two different P. jirovecii mitochondrial genes. The first of said two P. jirovecii mitochondrial genes is the P. jirovecii gene, the sequence of which codes for the Cytb protein or the P. jirovecii mitochondrial Small Sub-Unit (mtSSU) gene. The second of said two P. jirovecii mitochondrial genes is a P. jirovecii gene, the sequence of which transcribes into a P. jirovecii ribosomal RNA, e.g., be the mitochondrial P. jirovecii Large Sub-Unit (mtLSU) gene.
    Type: Grant
    Filed: April 15, 2016
    Date of Patent: February 1, 2022
    Assignees: INSTITUT PASTEUR, ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS, UNIVERSITE PARIS DIDEROT—PARIS 7
    Inventors: Alexandre Alanio, Stéphane Bretagne, Françoise Dromer, Aude Sturny-Leclere, Benjamin Hommel, Marion Benazra
  • MEANS FOR DIAGNOSING, PREDICTING OR MONITORING PNEUMOCYSTIS PNEUMONIA
    Publication number: 20180127825
    Abstract: The application relates to means for diagnosing, predicting or monitoring Pneumocystis pneumonia (PCP). The means of the application are also suitable for determining or predicting the efficacy of a drug or treatment against PCP in a human patient. The means of involve the detection and/or quantification, more particularly the quantification, of the RNA transcripts of two different P. jirovecii mitochondrial genes. The first of said two P. jirovecii mitochondrial genes is the P. jirovecii gene, the sequence of which codes for the Cytb protein or the P. jirovecii mitochondrial Small Sub-Unit (mtSSU) gene. The second of said two P. jirovecii mitochondrial genes is a P. jirovecii gene, the sequence of which transcribes into a P. jirovecii ribosomal RNA, e.g., be the mitochondrial P. jirovecii Large Sub-Unit (mtLSU) gene.
    Type: Application
    Filed: April 15, 2016
    Publication date: May 10, 2018
    Applicants: INSTITUT PASTEUR, ASSISTANCE PUBLIQUE- HOPITAUX DE PARIS, UNIVERSITE PARIS DIDEROT - PARIS 7
    Inventors: Alexandre ALANIO, Stéphane BRETAGNE, Françoise DROMER, Aude STURNY-LECLERE, Benjamin HOMMEL, Marion BENAZRA
  • Method for Determining the Susceptibility of a Cell Strain to Drugs
    Publication number: 20120276577
    Abstract: The present invention relates to a method for determining the susceptibility of a cell strain to a compound intended for controlling the growth of said cell strain, comprising: growing the cell strain in a first compound-free culture medium and in at least a second culture medium comprising the compound at a test concentration; obtaining mass-spectrometry spectra for a protein extract of the cell strain grown in the first culture medium and for a protein extract of the cell strain grown in the second culture medium; comparing the mass spectrometry spectra; deducing that the cell strain is sensitive to the compound at the test concentration if the mass spectrometry spectra are significantly different.
    Type: Application
    Filed: June 25, 2010
    Publication date: November 1, 2012
    Applicants: ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS, UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6)
    Inventors: Dominique Mazier, Carine Marinach-Patrice, Alexandre Alanio, Jean L. Golmard, Martine Palous, Annick Datry, Jean Y. Brossas
  • Means for identifying a strain isolated from a clinical sample at the species and/or subspecies level
    Patent number: 8155892
    Abstract: The invention relates to a method for identifying a strain isolated from a clinical sample, at the species and/or subspecies level, using MALDI-TOF-MS analysis comprising a step of classifying the germ in a group before performing the MALDI-TOF-MS analysis.
    Type: Grant
    Filed: July 8, 2009
    Date of Patent: April 10, 2012
    Assignees: Assistance Publique-Hopitaux de Paris (APHP), Universite Paris Descartes
    Inventors: Xavier Nassif, Jean-Luc Beretti, Etienne Carbonnelle, Agnès Ferroni, Marie Elisabeth Bougnoux, Nicolas Degand, Alexandre Alanio
  • Means for identifying a strain isolated from a clinical sample at the species and/or subspecies level
    Publication number: 20100116980
    Abstract: The invention relates to a method for identifying a strain isolated from a clinical sample, at the species and/or subspecies level, using MALDI-TOF-MS analysis comprising a step of classifying the germ in a group before performing the MALDI-TOF-MS analysis
    Type: Application
    Filed: July 8, 2009
    Publication date: May 13, 2010
    Inventors: Xavier Nassif, Jean-Luc Beretti, Etienne Carbonnelle, Agnès Ferroni, Marie Elisabeth Bougnoux, Nicolas Degand, Alexandre Alanio