Patents by Inventor Alexandre ARNOULT

Alexandre ARNOULT has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11702426
    Abstract: This invention relates to macrocyclic deaza-purinones derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.
    Type: Grant
    Filed: October 27, 2020
    Date of Patent: July 18, 2023
    Assignee: JANSSEN SCIENCES IRELAND UNLIMITED COMPANY
    Inventors: Jean-François Bonfanti, Jérôme Michel Claude Fortin, Philippe Muller, Frédéric Marc Maurice Doublet, Pierre Jean-Marie Bernard Raboisson, Eric Pierre Alexandre Arnoult
  • Patent number: 11486699
    Abstract: A method for measuring the deformation of a reflective surface of an object is provided. The measuring device includes a lighting pattern containing spots of light, a camera and an image-analyzing device, the lighting pattern and the camera being arranged so that, in the measurement position, the virtual or real image of the lighting pattern is visible to the detector of the camera via the surface, the image being representative of the deformation of the lit region. The method comprises the following steps: measuring a distance between the images of two spots of light; computing the ratio between this measured distance and a reference distance; computing, from this ratio, the enlargement in a defined direction; computing the deformation of the reflective surface in the defined direction.
    Type: Grant
    Filed: May 23, 2018
    Date of Patent: November 1, 2022
    Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Alexandre Arnoult, Jonathan Colin
  • Patent number: 11226288
    Abstract: A device for measuring a matter flux, including: at least one first light source to emit a first light beam having a measurement wavelength corresponding to the absorption wavelength of an element of interest of the matter flux; an optical connector; and a light sensor to receive, via the optical connector: an attenuated beam resulting from a transmission of the first light beam through the matter flux; and a non-attenuated beam resulting from a transmission of the first light beam without passing through the matter flux. The light sensor is one-dimensional and the optical connector is positioned relative to the light sensor so that the center of the optical connector is aligned with the center of the light sensor, the non-attenuated beam is spectrally directed towards a first part of the light sensor and the attenuated beam is spectrally directed towards a second part of the light sensor.
    Type: Grant
    Filed: July 8, 2019
    Date of Patent: January 18, 2022
    Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventor: Alexandre Arnoult
  • Publication number: 20210278342
    Abstract: A device for measuring a matter flux, including: at least one first light source to emit a first light beam having a measurement wavelength corresponding to the absorption wavelength of an element of interest of the matter flux; an optical connector; and a light sensor to receive, via the optical connector: an attenuated beam resulting from a transmission of the first light beam through the matter flux; and a non-attenuated beam resulting from a transmission of the first light beam without passing through the matter flux. The light sensor is one-dimensional and the optical connector is positioned relative to the light sensor so that the center of the optical connector is aligned with the center of the light sensor, the non-attenuated beam is spectrally directed towards a first part of the light sensor and the attenuated beam is spectrally directed towards a second part of the light sensor.
    Type: Application
    Filed: July 8, 2019
    Publication date: September 9, 2021
    Inventor: Alexandre ARNOULT
  • Publication number: 20210122760
    Abstract: This invention relates to macrocyclic deaza-purinones derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.
    Type: Application
    Filed: October 27, 2020
    Publication date: April 29, 2021
    Inventors: Jean-François BONFANTI, Jérôme Michel Claude FORTIN, Philippe MULLER, Frédéric Marc Maurice DOUBLET, Pierre Jean-Marie Bernard RABOISSON, Eric Pierre Alexandre ARNOULT
  • Patent number: 10829494
    Abstract: This invention relates to macrocyclic deaza-purinones derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.
    Type: Grant
    Filed: April 19, 2019
    Date of Patent: November 10, 2020
    Assignee: JANSSEN SCIENCES IRELAND UNLIMITED COMPANY
    Inventors: Jean-François Bonfanti, Jérôme Michel Claude Fortin, Philippe Muller, Frédéric Marc Maurice Doublet, Pierre Jean-Marie Bernard Raboisson, Eric Pierre Alexandre Arnoult
  • Patent number: 10822349
    Abstract: This invention relates macrocyclic purine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.
    Type: Grant
    Filed: May 6, 2019
    Date of Patent: November 3, 2020
    Assignee: JANSSEN SCIENCES IRELAND UNLIMITED COMPANY
    Inventors: Jean-François Bonfanti, Jérôme Michel Claude Fortin, Frédéric Marc Maurice Doublet, Pierre Jean-Marie Bernard Raboisson, Eric Pierre Alexandre Arnoult
  • Publication number: 20200158497
    Abstract: A method for measuring the deformation of a reflective surface of an object is provided. The measuring device includes a lighting pattern containing spots of light, a camera and an image-analyzing device, the lighting pattern and the camera being arranged so that, in the measurement position, the virtual or real image of the lighting pattern is visible to the detector of the camera via the surface, the image being representative of the deformation of the lit region. The method comprises the following steps: measuring a distance between the images of two spots of light; computing the ratio between this measured distance and a reference distance; computing, from this ratio, the enlargement in a defined direction; computing the deformation of the reflective surface in the defined direction.
    Type: Application
    Filed: May 23, 2018
    Publication date: May 21, 2020
    Inventors: Alexandre ARNOULT, Jonathan COLIN
  • Patent number: 10526331
    Abstract: The present invention is related to novel compounds of formula (I) that inhibit the activity of the FabI enzyme which are therefore useful in the treatment of bacterial infections. It further relates to pharmaceutical compositions comprising these compounds, and chemical processes for preparing these compounds.
    Type: Grant
    Filed: February 26, 2019
    Date of Patent: January 7, 2020
    Assignee: Janssen Sciences Ireland Unlimited Company
    Inventors: Jerôme Emile Georges Guillemont, David Francis Alain Lançois, Magali Madeleine Simone Motte, Anil Koul, Wendy Mia Albert Balemans, Eric Pierre Alexandre Arnoult
  • Patent number: 10501463
    Abstract: The present invention is related to novel compounds of formula (I) that inhibit the activity of the FabI enzyme which are therefore useful in the treatment of bacterial infections. It further relates to pharmaceutical compositions comprising these compounds, and chemical processes for preparing these compounds.
    Type: Grant
    Filed: November 16, 2018
    Date of Patent: December 10, 2019
    Assignee: Janssen Sciences Ireland Unlimited Company
    Inventors: Jerôme Emile Georges Guillemont, David Francis Alain Lançois, Magali Madeleine Simone Motte, Anil Koul, Wendy Mia Albert Balemans, Eric Pierre Alexandre Arnoult
  • Publication number: 20190330234
    Abstract: This invention relates macrocyclic purine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.
    Type: Application
    Filed: May 6, 2019
    Publication date: October 31, 2019
    Inventors: Jean-François BONFANTI, Jérôme Michel Claude FORTIN, Frédéric Marc Maurice DOUBLET, Pierre Jean-Marie Bernard RABIOSSON, Eric Pierre Alexandre ARNOULT
  • Publication number: 20190330222
    Abstract: This invention relates to macrocyclic deaza-purinones derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.
    Type: Application
    Filed: April 19, 2019
    Publication date: October 31, 2019
    Inventors: Jean-François BONFANTI, Jérôme Michel Claude FORTIN, Philippe MULLER, Frédéric Marc Maurice DOUBLET, Pierre Jean-Marie Bernard RABOISSON, Eric Pierre Alexandre ARNOULT
  • Publication number: 20190194194
    Abstract: The present invention is related to novel compounds of formula (I) that inhibit the activity of the FabI enzyme which are therefore useful in the treatment of bacterial infections. It further relates to pharmaceutical compositions comprising these compounds, and chemical processes for preparing these compounds.
    Type: Application
    Filed: February 26, 2019
    Publication date: June 27, 2019
    Inventors: Jerôme Emile Georges Guillemont, David Francis Alain Lançois, Magali Madeleine Simone Motte, Anil Koul, Wendy Mia Albert Balemans, Eric Pierre Alexandre Arnoult
  • Patent number: 10280180
    Abstract: This invention relates macrocyclic purine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.
    Type: Grant
    Filed: July 12, 2013
    Date of Patent: May 7, 2019
    Assignee: Janssen Sciences Ireland UC
    Inventors: Jean-Francois Bonfanti, Jerome Michel Claude Fortin, Philippe Muller, Frederic Marc Maurice Doublet, Pierre Jean-Marie Bernard Raboisson, Eric Pierre Alexandre Arnoult
  • Patent number: 10266543
    Abstract: This invention relates to macrocyclic deaza-purinones derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.
    Type: Grant
    Filed: March 28, 2014
    Date of Patent: April 23, 2019
    Assignee: Janssen Sciences Ireland UC
    Inventors: Jean-François Bonfanti, Jérôme Michel Claude Fortin, Philippe Muller, Frédéric Marc Maurice Doublet, Pierre Jean-Marie Bernard Raboisson, Eric Pierre Alexandre Arnoult
  • Publication number: 20190084982
    Abstract: The present invention is related to novel compounds of formula (I) that inhibit the activity of the FabI enzyme which are therefore useful in the treatment of bacterial infections. It further relates to pharmaceutical compositions comprising these compounds, and chemical processes for preparing these compounds.
    Type: Application
    Filed: November 16, 2018
    Publication date: March 21, 2019
    Inventors: Jerôme Emile Georges Guillemont, David Francis Alain Lançois, Magali Madeleine Simone Motte, Anil Koul, Wendy Mia Albert Balemans, Eric Pierre Alexandre Arnoult
  • Patent number: 10155759
    Abstract: The present invention is related to novel compounds of formula (I) that inhibit the activity of the FabI enzyme which are therefore useful in the treatment of bacterial infections. It further relates to pharmaceutical compositions comprising these compounds, and chemical processes for preparing these compounds.
    Type: Grant
    Filed: December 18, 2017
    Date of Patent: December 18, 2018
    Assignee: Janssen Sciences Ireland UC
    Inventors: Jerôme Emile Georges Guillemont, David Francis Alain Lançois, Magali Madeleine Simone Motte, Anil Koul, Wendy Mia Albert Balemans, Eric Pierre Alexandre Arnoult
  • Publication number: 20180105525
    Abstract: The present invention is related to novel compounds of formula (I) that inhibit the activity of the FabI enzyme which are therefore useful in the treatment of bacterial infections. It further relates to pharmaceutical compositions comprising these compounds, and chemical processes for preparing these compounds.
    Type: Application
    Filed: December 18, 2017
    Publication date: April 19, 2018
    Inventors: Jerôme Emile Georges Guillemont, David Francis Alain Lançois, Magali Madeleine Simone Motte, Anil Koul, Wendy Mia Albert Balemans, Eric Pierre Alexandre Arnoult
  • Patent number: 9884864
    Abstract: The present invention is related to novel compounds of formula (I) that inhibit the activity of the FabI enzyme which are therefore useful in the treatment of bacterial infections. It further relates to pharmaceutical compositions comprising these compounds, and chemical processes for preparing these compounds.
    Type: Grant
    Filed: March 9, 2017
    Date of Patent: February 6, 2018
    Assignee: Janssen Sciences Ireland UC
    Inventors: Jerôme Emile Georges Guillemont, David Francis Alain Lançois, Magali Madeleine Simone Motte, Anil Koul, Wendy Mia Albert Balemans, Eric Pierre Alexandre Arnoult
  • Publication number: 20170174683
    Abstract: The present invention is related to novel compounds of formula (I) that inhibit the activity of the FabI enzyme which are therefore useful in the treatment of bacterial infections. It further relates to pharmaceutical compositions comprising these compounds, and chemical processes for preparing these compounds.
    Type: Application
    Filed: March 9, 2017
    Publication date: June 22, 2017
    Inventors: Jerôme Emile Georges Guillemont, David Francis Alain Lançois, Magali Madeleine Simone Motte, Anil Koul, Wendy Mia Albert Balemans, Eric Pierre Alexandre Arnoult