Patents by Inventor Alexandre BONE

Alexandre BONE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20260108305
    Abstract: The invention relates to a computer-implemented method of liver resection surgery planning, comprising the steps of: processing (E2) preoperative computed tomographic images (10) of a patient to generate liver, liver lesion (ss) and venous vessels segmentations; pruning the venous vessels segmentation to retain only major vessels and determining (E3) a primary hepatic zone (PHZ) from the retained major vessels; determining (E4) at least one quantitative feature from the primary hepatic zone, the liver segmentation and the liver lesion(s) segmentation; processing (E5) the determined quantitative features with a classification model to determine a liver resection complexity score for the patient.
    Type: Application
    Filed: July 27, 2023
    Publication date: April 23, 2026
    Applicants: GUERBET, INSTITUT NATIONAL DE RECHERCHE EN INFORMATIQUE ET EN AUTOMATIQUE, INSERM (Institut National de la Santé et de la Recherche Médicale), ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS, UNIVERSITE PARIS-SACLAY
    Inventors: Omar ALI, Alexandre BONE, Marc-Michel ROHÉ, Eric VIBERT, Irène VIGNON-CLEMENTEL
  • Publication number: 20250049405
    Abstract: The present invention relates to method for medical imaging, the method being characterized in that it comprises the implementation, by a data processor (11b) of a second server (1b), of steps of: (a) Obtaining at least one candidate pre-contrast image and a candidate contrast image respectively depicting a body part prior to and after an injection of a first dose of contrast agent, wherein said first dose is higher than a predetermined low dose, the predetermined reduced dose being lower than a predetermined standard dose; a convolutional neural network, CNN, being trained to reconstruct, from at least a pre-contrast input image and a low dose contrast input image respectively depicting a body part prior to and after an injection of said low dose of contrast agent, a standard dose contrast image depicting said body part after an injection of said standard dose of contrast agent; (b) Simulating an injection of a second dose of contrast agent which is higher than the standard dose, wherein said simulating comp
    Type: Application
    Filed: December 20, 2022
    Publication date: February 13, 2025
    Applicants: GUERBET, INSTITUT GUSTAVE ROUSSY
    Inventors: ALEXANDRE BONE, Marc-Michel ROHÉ, Nathalie LASSAU, Samy AMMARI, Philippe ROBERT
  • Publication number: 20240062061
    Abstract: The present invention relates to a method for processing an inputted perfusion sequence, by means of a convolutional neural network, CNN, the method being characterized in that it comprises the implementation, by a data processor (11b) of a second server (1b), of steps of: (b) extracting, using an encoder branch of the CNN, a plurality of initial n+1-dimensional features maps representative of the inputted perfusion sequence at different scales, n?3, said CNN further comprising a decoder branch and skip connections between the encoder branch and the decoder branch, each skip connection projecting the initial n+1-dimensional features maps into initial n-dimensional feature maps; (c) generating, using said decoder branch of the CNN, a plurality of enriched n-dimensional feature maps also representative of representative of the inputted perfusion sequence at different scales, each enriched n-dimensional feature map incorporating the information from the initial n-dimensional feature maps of smaller or equal scal
    Type: Application
    Filed: December 20, 2021
    Publication date: February 22, 2024
    Applicant: GUERBET
    Inventors: Alexandre BONE, Julien VERON VIALARD, Philippe ROBERT, Marc-Michel ROHÉ