Patents by Inventor Alexandre Charles
Alexandre Charles has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12373826Abstract: The present description concerns a method of implementation of an NFC transaction between a mobile terminal and a distant module. The terminal includes a processor hosting an application establishing the NFC transaction, a near-field communication module, and a secure element distinct from the processor. The method includes at least the following successive steps: (a) the near-field communication module ciphers first data sent by the distant module by using a first key supplied by the secure element and (b) the first application deciphers the first data by using a second key supplied by the secure elements.Type: GrantFiled: November 22, 2022Date of Patent: July 29, 2025Assignees: STMicroelectronics (Rousset) SAS, STMicroelectronics BelgiumInventors: Olivier Van Nieuwenhuyze, Alexandre Charles
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Patent number: 12357282Abstract: An interstitial fluid removal device including a first needle, a second needle, a fluid injector and an interstitial fluid extractor. The first needle is configured for insertion in a tissue of a multicellular organism to provide a fluid inlet channel. The second needle is configured for insertion in a tissue of a multicellular organism to provide an interstitial fluid outlet channel. The fluid injector is arranged in fluid communication with both a fluid source and the first needle and configured to inject a fluid in the tissue of the multicellular organism. The fluid extractor is arranged in fluid communication with the second needle and configured to extract interstitial fluid from the tissue of the multicellular organism. The fluid injector and the fluid extractor are independently and/or simultaneously operable with respect to each other.Type: GrantFiled: November 19, 2020Date of Patent: July 15, 2025Assignee: IMCOMET B.V.Inventors: Alexandre Charles Roger Motta, Varsha Sakina Thakoersing, Richardus Paulus Anton Oranje
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Patent number: 12357661Abstract: Provided are delivery immunostimulatory bacteria that have enhanced colonization of tumors, the tumor microenvironment and/or tumor-resident immune cells, and enhanced anti-tumor activity. The immunostimulatory bacteria are modified by deletion of genes encoding the flagella, or by modification of the genes so that functional flagella are not produced, and/or are modified by deletion of pagP or modification of pagP to produce inactive PagP product. As a result, the immunostimulatory bacteria are flagellin? and/or pagP?. The immunostimulatory bacteria optionally have additional genomic modifications so that the bacteria are adenosine or purine auxotrophs. The bacteria optionally are one or more of asd?, purI?, and msbB?.Type: GrantFiled: September 29, 2020Date of Patent: July 15, 2025Assignee: Actym Therapeutics, Inc.Inventors: Christopher D. Thanos, Laura Hix Glickman, Justin Skoble, Alexandre Charles Michel Iannello
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Patent number: 12341815Abstract: The present description discloses a secure element and a communication method comprising a router managing first messages using a first communication protocol between applications of the secure element and the outside of the secure element, and a software layer performing a processing at the level of the router. The software layer is adapted to verify the compatibility of a second communication protocol, different from the first one, with which second messages are received, in the absence of a compatibility, convert the second messages into the first communication protocol, and transmit the second messages to the router.Type: GrantFiled: September 24, 2021Date of Patent: June 24, 2025Assignees: STMICROELECTRONICS (ROUSSET) SAS, STMICROELECTRONICS BELGIUMInventors: Olivier Van Nieuwenhuyze, Alexandre Charles
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Patent number: 12323789Abstract: The present description discloses a secure element and a communication method, configured to implement at least one first application, and including a circuit configured to record routing data and a list and parameters of communication protocols compatible with the first application, verify the compatibility of a first communication protocol used by first messages intended for the first application with the protocols of the list, convert the first messages into second messages by using a second communication protocol in response to the first protocol not being compatible with at least one of the protocols of the list, and direct the second messages to the first application by using the routing data of the first application.Type: GrantFiled: September 24, 2021Date of Patent: June 3, 2025Assignees: STMicroelectronics (ROUSSET) SAS, STMicroelectronics BelgiumInventors: Olivier Van Nieuwenhuyze, Alexandre Charles
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Patent number: 12226439Abstract: Provided are delivery immunostimulatory bacteria that have enhanced colonization of tumors, the tumor microenvironment and/or tumor-resident immune cells, and enhanced anti-tumor activity. The immunostimulatory bacteria are modified by deletion of genes encoding the flagella, or by modification of the genes so that functional flagella are not produced, and/or are modified by deletion of pagP or modification of pagP to produce inactive PagP product. As a result, the immunostimulatory bacteria are flagellin? and/or pagP?. The immunostimulatory bacteria optionally have additional genomic modifications so that the bacteria are adenosine or purine auxotrophs. The bacteria optionally are one or more of asd?, purI?, and msbB?.Type: GrantFiled: September 21, 2022Date of Patent: February 18, 2025Assignee: Actym Therapeutics, Inc.Inventors: Christopher D. Thanos, Laura Hix Glickman, Justin Skoble, Alexandre Charles Michel Iannello
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Patent number: 12201653Abstract: Provided are delivery immunostimulatory bacteria that have enhanced colonization of tumors, the tumor microenvironment and/or tumor-resident immune cells, and enhanced anti-tumor activity. The immunostimulatory bacteria are modified by deletion of genes encoding the flagella, or by modification of the genes so that functional flagella are not produced, and/or are modified by deletion of pagP or modification of pagP to produce inactive PagP product. As a result, the immunostimulatory bacteria are flagellin? and/or pagP?. The immunostimulatory bacteria optionally have additional genomic modifications so that the bacteria are adenosine or purine auxotrophs. The bacteria optionally are one or more of asd?, purI?, and msbB?.Type: GrantFiled: May 18, 2022Date of Patent: January 21, 2025Assignee: Actym Therapeutics, Inc.Inventors: Christopher D. Thanos, Laura Hix Glickman, Justin Skoble, Alexandre Charles Michel Iannello
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Publication number: 20240293478Abstract: Provided are methods for treating cancer by converting tumor-resident macrophages into a hybrid M1/M2 macrophage phenotype; this phenotype has attributes that are advantageous for cancer therapy. Hybrid markers include (lower than M2, higher than M1): SPP1, CD209, and CD206, and induced markers include MERTK, C1QC, IFNa, IFNb, CXCL10, 4-1BBL, and MYC. The methods include administering a therapeutic that effects the phenotypic conversion. Therapeutics, such as delivery vehicles, including immunostimulatory bacteria with genome modifications, are designed so that they do not induce or result in a sufficient TLR2, TLR4, TLR5 response to inhibit type I IFN. The therapeutics also encode a payload that encodes immunostimulatory proteins, such as a cytokine and a modified cytosolic DNA/RNA sensor that constitutively induces type I IFN, such as a modified STING protein.Type: ApplicationFiled: May 9, 2024Publication date: September 5, 2024Inventors: Akshata Udyavar, Laura Hix Glickman, Chingnam Cheung, Alexandre Charles Michel Iannello, Bret Nicholas Peterson, Nicholas Boyce Woodall, Christopher D. Thanos
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Publication number: 20240221315Abstract: One variation of a method for modeling a human body includes: driving a sensor block along a path above a platform occupied by a user and recording a sequence of depth images and color images, via the sensor block, at each capture position in a sequence of capture positions along the path; compiling the set of depth images into a low-density 3D model of the user and a high-density 3D model of the user; extracting a set of color patches, from the sequence of color images, corresponding to discrete regions on a surface of the low-density 3D model of the user; projecting the set of color patches onto the surface of the low-density 3D model to generate a 3D color model of the user; and extracting a value of a dimension, projected from the low-density 3D color model onto the high-density 3D model, from the high-density 3D model.Type: ApplicationFiled: January 11, 2024Publication date: July 4, 2024Inventor: Alexandre Charles M. Wayenberg
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Patent number: 12024709Abstract: Provided are delivery immunostimulatory bacteria that have enhanced colonization of tumors, the tumor microenvironment and/or tumor-resident immune cells, and enhanced anti-tumor activity. The immunostimulatory bacteria are modified by deletion of genes encoding the flagella or by modification of the genes so that functional flagella are not produced, and/or are modified by deletion of pagP or modification of pagP to produce inactive PagP product. As a result, the immunostimulatory bacteria are flagellin? and/or pagP?. The immunostimulatory bacteria optionally have additional genomic modifications so that the bacteria are adenosine and/or purine auxotrophs. The bacteria optionally are one or more of asd?, purI? and msbB?.Type: GrantFiled: March 19, 2020Date of Patent: July 2, 2024Assignee: Actym Therapeutics, Inc.Inventors: Christopher D. Thanos, Laura Hix Glickman, Justin Skoble, Alexandre Charles Michel Iannello, Haixing Kehoe
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Patent number: 11962616Abstract: A method and associated circuits protect data stored in a secure data circuit of a telecommunication device equipped with a near-field communication (NFC) router, a microcontroller, and the secure data circuit. In the method, each message received with the NFC router is parsed to retrieve a communication pipe identifier and an instruction code. The communication pipe identifier and the instruction code are compared to corresponding information in a filter table. Instruction codes of particular messages that attempt to modify a communication pipe by reassigning one end of the communication pipe from the port of the NFC router to a different circuit are acted upon. These messages are blocked from reaching the secure data circuit when the instruction code is not authorized in the filter table, and these messages are permitted when the instruction code is authorized in the filter table.Type: GrantFiled: January 11, 2021Date of Patent: April 16, 2024Assignees: PROTON WORLD INTERNATIONAL N.V., STMICROELECTRONICS (ROUSSET) SASInventors: Olivier Van Nieuwenhuyze, Thierry Huque, Alexandre Charles
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Publication number: 20240114324Abstract: A device, including a main element and a set of at least two auxiliary elements, the main element including a master SWP interface, each auxiliary element including a slave SWP interface connected to the master SWP interface of the NFC element through a controllably switchable SWP link and management circuit configured to control the SWP link switching for selectively activating at once only one slave SWP interface on the SWP link.Type: ApplicationFiled: November 30, 2023Publication date: April 4, 2024Inventors: Thierry Meziache, Pierre Rizzo, Alexandre Charles, Juergen Boehler
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Patent number: 11934329Abstract: Data exchanges between an ultra-wide band communication module and a secure element are controlled such that the data exchanges pass through a near-field communication router. The near-field communication router controls routing of the data exchanges so that the data exchanges do not pass through a host circuit that is also coupled to the near-field communication router.Type: GrantFiled: January 20, 2020Date of Patent: March 19, 2024Assignee: STMicroelectronics (Rousset) SASInventors: Alexandre Tramoni, Alexandre Charles
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Patent number: 11908078Abstract: One variation of a method for modeling a human body includes: driving a sensor block along a path above a platform occupied by a user and recording a sequence of depth images and color images, via the sensor block, at each capture position in a sequence of capture positions along the path; compiling the set of depth images into a low-density 3D model of the user and a high-density 3D model of the user; extracting a set of color patches, from the sequence of color images, corresponding to discrete regions on a surface of the low-density 3D model of the user; projecting the set of color patches onto the surface of the low-density 3D model to generate a 3D color model of the user; and extracting a value of a dimension, projected from the low-density 3D color model onto the high-density 3D model, from the high-density 3D model.Type: GrantFiled: December 23, 2021Date of Patent: February 20, 2024Assignee: Shape Labs Inc.Inventor: Alexandre Charles M. Wayenberg
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Patent number: 11889397Abstract: A device, including a main element and a set of at least two auxiliary elements, said main element including a master SWP interface, each auxiliary element including a slave SWP interface connected to said master SWP interface of said NFC element through a controllably switchable SWP link and management means configured to control said SWP link switching for selectively activating at once only one slave SWP interface on said SWP link.Type: GrantFiled: January 27, 2022Date of Patent: January 30, 2024Assignees: STMicroelectronics (Rousset) SAS, STMICROELECTRONICS GMBHInventors: Thierry Meziache, Pierre Rizzo, Alexandre Charles, Juergen Boehler
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Patent number: 11779612Abstract: Provided are delivery immunostimulatory bacteria that have enhanced colonization of tumors, the tumor microenvironment and/or tumor-resident immune cells, and enhanced anti-tumor activity. The immunostimulatory bacteria are modified by deletion of genes encoding the flagella or modification of the genes so that functional flagella are not produced, and/or are modified by deletion of pagP or modification of pagP to produce inactive PagP product. As a result, the immunostimulatory bacteria are flagellin? and/or pagP?. The immunostimulatory bacteria optionally have additional genomic modifications so that the bacteria are adenosine or purine auxotrophs. The bacteria optionally are one or more of asd?, purI? and msbB?.Type: GrantFiled: July 23, 2019Date of Patent: October 10, 2023Assignee: ACTYM THERAPEUTICS, INC.Inventors: Christopher D. Thanos, Laura Hix Glickman, Justin Skoble, Alexandre Charles Michel Iannello
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Publication number: 20230186295Abstract: The present description concerns a method of implementation of an NFC transaction between a mobile terminal and a distant module. The terminal includes a processor hosting an application establishing the NFC transaction, a near-field communication module, and a secure element distinct from the processor. The method includes at least the following successive steps: (a) the near-field communication module sends, to the first application, first data sent by the distant module and ciphered by the secure element; and (b) the first application asks the secure element to decipher the first data.Type: ApplicationFiled: November 22, 2022Publication date: June 15, 2023Inventors: Olivier Van Nieuwenhuyze, Alexandre Charles
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Publication number: 20230189002Abstract: In an embodiment a method for implementing a NFC transaction between a mobile terminal and a distant module is disclosed. The terminal includes a processor hosting an application configured to establish the NFC transaction, a near-field communication module, and a secure element distinct from the processor. The method includes storing, by the near-field communication module in the secure element, first data from the distant module, sending, by the near-field communication module, second data to the application notifying it that the first data have been stored in the secure element and requesting, by the application, the first data from the secure element.Type: ApplicationFiled: December 13, 2022Publication date: June 15, 2023Inventors: Olivier Van Nieuwenhuyze, Alexandre Charles
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Publication number: 20230186294Abstract: The present description concerns a method of implementation of an NFC transaction between a mobile terminal and a distant module. The terminal includes a processor hosting an application establishing the NFC transaction, a near-field communication module, and a secure element distinct from the processor. The method includes at least the following successive steps: (a) the near-field communication module ciphers first data sent by the distant module by using a first key supplied by the secure element and (b) the first application deciphers the first data by using a second key supplied by the secure elements.Type: ApplicationFiled: November 22, 2022Publication date: June 15, 2023Inventors: Olivier Van Nieuwenhuyze, Alexandre Charles
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Publication number: 20230186278Abstract: In an embodiment a method for implementing a NFC transaction between a mobile terminal and a distant module is disclosed. The terminal includes a processor hosting an application configured to establish the NFC transaction and an interface software configured to execute instructions of the application, a near-field communication module and a secure element distinct from the processor.Type: ApplicationFiled: December 9, 2022Publication date: June 15, 2023Inventors: Olivier Van Nieuwenhuyze, Alexandre Charles, Alexandra Ducati Manas