Patents by Inventor Alexandre de la Fuente Gonzalez

Alexandre de la Fuente Gonzalez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR ISOLATING NUCLEIC ACIDS
    Publication number: 20220411849
    Abstract: The invention relates to an in vitro method for isolating nucleic acids associated to or contained inside extracellular vesicles (EVs) from a sample based on the formation of a DMB-EVs precipitate and the isolation of the nucleic acids present in the precipitate. The invention also relates to the use of the method of the invention for diagnosing or for determining the susceptibility of a subject to a disease, for determining the prognosis or for monitoring the progression of a disease, for monitoring the effect of a therapy, for identifying compounds suitable for the treatment of a disease, or for designing a personalized therapy or selecting a patient susceptible to being treated with a therapy for the prevention and/or treatment of a disease. In addition, the invention also relates to a kit comprising dimethylmethylene blue (DMB) and a reagent capable of isolating nucleic acids from EVs, and to its use.
    Type: Application
    Filed: November 4, 2020
    Publication date: December 29, 2022
    Inventors: Alexandre DE LA FUENTE GONZÁLEZ, Miguel ABAL POSADA, Laura MUINELO ROMAY, Carlos CASAS AROZAMENA
  • Agent for capturing tumor cells and methods of use thereof
    Patent number: 10111935
    Abstract: The present invention relates to a composition for modulating tumor cell dissemination, in particular metastatic cancer cells. In particular, the invention relates to an agent for modulating metastatic tumor cell dissemination for use in the treatment and/or prevention of a metastatic cancer wherein the agent comprises an extracellular matrix (ECM) protein carried on a polycarbonate polyurethane matrix, and wherein the agent binds to tumor cells when implanted in a body. The invention also relates to a product, comprising an agent for modulating metastatic tumor cell dissemination, and to a method of treatment or prevention of cancer.
    Type: Grant
    Filed: April 30, 2015
    Date of Patent: October 30, 2018
    Assignees: FUNDACIÖN PEDRO BARRIÉ DE LA MAZA, CONDO DE FENOSA, SERGAS, UNIVERSITY OF SANTIAGO DE COMPOSTELA, FUNDACION RAMÓN DOMINGUEZ, BIOMERIX CORPORATION
    Inventors: Alexandre De La Fuente Gonzalez, Rafael Lopez, Miguel Abal Posada, Lawrence Patrick Lavelle, Jr.
  • Methods of capturing tumor cells
    Patent number: 10022400
    Abstract: The present invention relates to a composition for modulating tumor cell dissemination, in particular metastatic cancer cells. In particular, the invention relates to an agent for modulating metastatic tumor cell dissemination for use in the treatment and/or prevention of a metastatic cancer wherein the agent is a capture agent and/or a chemoattractant for tumor cells. The invention also relates to a product, comprising an agent for modulating metastatic tumor cell dissemination, and to a method of treatment or prevention of cancer.
    Type: Grant
    Filed: November 26, 2013
    Date of Patent: July 17, 2018
    Assignees: Fundacion Ramon Dominguez, SERGAS
    Inventors: Alexandre de la Fuente Gonzalez, Rafael Lopez, Miguel Abal Posada
  • AGENT, PRODUCT AND USE
    Publication number: 20170246258
    Abstract: The present invention relates to a composition for modulating tumor cell dissemination, in particular metastatic cancer cells. In particular, the invention relates to an agent for modulating metastatic tumor cell dissemination for use in the treatment and/or prevention of a metastatic cancer wherein the agent an extracellular matrix (ECM) protein carried on a polycarbonate polyurethane matrix. The invention also relates to a product, comprising an agent for modulating metastatic tumor cell dissemination, and to a method of treatment or prevention of cancer.
    Type: Application
    Filed: April 30, 2015
    Publication date: August 31, 2017
    Applicants: FUNDACIÓN PEDRO BARRIÉ DE LA MAZA, CONDE DE FENOSA, SERGAS, UNIVERSITY OF SANTIAGO DE COMPOSTELA, FUNDACION RAMÓN DOMINGUEZ, BIOMERIX CORPORATION
    Inventors: Alexandre DE LA FUENTE GONZALEZ, Rafael LOPEZ, Miguel Abal POSADA, Lawrence Patrick LAVELLE, Jr.
  • AGENT, PRODUCT AND USE
    Publication number: 20170049860
    Abstract: The present invention relates to a composition for modulating tumor cell dissemination, in particular metastatic cancer cells. In particular, the invention relates to an agent for modulating metastatic tumor cell dissemination for use in the treatment and/or prevention of a metastatic cancer wherein the agent an extracellular matrix (ECM) protein carried on a polycarbonate polyurethane matrix. The invention also relates to a product, comprising an agent for modulating metastatic tumor cell dissemination, and to a method of treatment or prevention of cancer.
    Type: Application
    Filed: April 30, 2015
    Publication date: February 23, 2017
    Applicants: Fundacion Pedro Barrie De La Maza,Conde De Fenosa, Sergas, University of Santiago De Compostela, Fundacion Ramon Dominguez, Biomerix Corporation
    Inventors: Alexandre DE LA FUENTE GONZALEZ, Rafael LOPEZ, Miguel Abal POSADA, Lawrence Patrick LAVELLE, JR.
  • AGENT, PRODUCT AND USE
    Publication number: 20150290245
    Abstract: The present invention relates to a composition for modulating tumor cell dissemination, in particular metastatic cancer cells. In particular, the invention relates to an agent for modulating metastatic tumor cell dissemination for use in the treatment and/or prevention of a metastatic cancer wherein the agent is a capture agent and/or a chemoattractant for tumor cells. The invention also relates to a product, comprising an agent for modulating metastatic kidneys tumor cell dissemination, and to a method of treatment or prevention of cancer.
    Type: Application
    Filed: November 26, 2013
    Publication date: October 15, 2015
    Inventors: Alexandre de la Fuente Gonzalez, Rafael Lopez, Miguel Abal Posada