Patents by Inventor Alexandre Debacker

Alexandre Debacker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TMEM173 saRNA Compositions and Methods of Use
    Publication number: 20240175033
    Abstract: The disclosure relates to a saRNAs useful in upregulating the expression of a target gene and therapeutic compositions comprising the saRNA, wherein the target gene is TMEM173. Methods of using the saRNA and the therapeutic compositions are also provided.
    Type: Application
    Filed: March 25, 2022
    Publication date: May 30, 2024
    Applicant: MiNA Therapeutics Limited
    Inventors: Choon Ping Tan, Laura Sinigaglia, Valentin Gomez Martinez, Brid Ryan, Pål Sætrom, Siv Anita Hegre, Alexandre Debacker
  • OLIGONUCLEOTIDE CONJUGATE COMPOSITIONS AND METHODS OF USE
    Publication number: 20220281911
    Abstract: The disclosure relates to GalNAc moieties comprising at least one GalNAc monomer. The disclosure also relates to GalNAc-oligonucleotide conjugates comprising GalNAc moieties and oligonucleotides, e.g., saRNAs or siRNAs useful in regulating the expression of a target gene. Methods of using the GalNAc-oligonucleotide conjugates are also provided.
    Type: Application
    Filed: August 19, 2020
    Publication date: September 8, 2022
    Inventors: Alexandre Debacker, Jon Voutila, Lee Mitchell, Catherine M. McKeen
  • SIRT1-SARNA COMPOSITIONS AND METHODS OF USE
    Publication number: 20220211740
    Abstract: The disclosure relates to a saRNAs useful in upregulating the expression of the SIRT1 gene and therapeutic compositions comprising the saRNA. Methods of using the saRNA and the therapeutic compositions are also provided.
    Type: Application
    Filed: April 9, 2020
    Publication date: July 7, 2022
    Inventors: Pinelopi Andrikakou, Alexandre Debacker, Vikash Reebye