Patents by Inventor Alexandre Hertig

Alexandre Hertig has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ENDOTHELIAL CELLS ACTIVATION BIOMARKERS CHARACTERIZING ANTIBODY MEDIATED REJECTION AND USES THEREOF
    Publication number: 20150118224
    Abstract: Described herein are methods and kits for the detection of endothelial cell injury and/or activation and to the diagnostic of transplant antibody mediated rejection (ABMR). The invention further relates to methods and kits for diagnosing endothelial to mesenchymal transition (EndMT). In various embodiments, the methods comprise assessing expression of one, two or three biomarkers selected from Fascin1, Vimentin and Hsp47.
    Type: Application
    Filed: April 4, 2013
    Publication date: April 30, 2015
    Inventors: Yi-Chun Xu-Dubois, Eric Rondeau, Julie Peltier, Alexandre Hertig, Isabelle Brocheriou
  • METHOD FOR QUANTIFYING RENAL MARKERS BY ASSAYING URINE
    Publication number: 20140378334
    Abstract: The invention pertains to a method of in vitro diagnosis of pathologies in a patient. According to the invention, the method comprises the following steps: a) obtaining a urine sample from said patient, b) detecting, in said sample, at least one marker of said pathology and at least one specific marker of the urothelial cells and/or the urothelial microparticles, and c) determining a threshold of expression of said at least one marker of said pathology by normalization of said marker of said pathology by said at least one specific marker of the urothelial cells and/or the urothelial microparticles.
    Type: Application
    Filed: October 19, 2012
    Publication date: December 25, 2014
    Inventors: Pierre Galichon, Eric Rondeau, Isabelle Brocheriou, Yi-Chun Xu-Dubois, Alexandre Hertig